Search Results - "Poddubikov, A. V."
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Changes in Innate Immunity and Microbiome in Different Aging Phenotypes
Published in Bulletin of experimental biology and medicine (01-09-2024)“…The indicators of innate immunity and the composition of the microbiome in the nasopharyngeal mucosa in centenarians with different aging phenotypes were…”
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Biofilm Formation by Lactobacillus Strains of Modern Probiotics and Their Antagonistic Activity against Opportunistic Bacteria
Published in Bulletin of experimental biology and medicine (01-08-2024)“…The species identity of the studied lactobacillus strains was confirmed by matrix-activated laser desorption/ionization with time-of-flight ion separation…”
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Analysis of Toxicity of Recombinant Pneumolysin from Streptococcus pneumoniae
Published in Bulletin of experimental biology and medicine (01-05-2024)“…We studied toxicity of recombinant Streptococcus pneumoniae pneumolysin protein in experiments on mice and its cytopathogenic effect on cultures of Vero green…”
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Preparation a Recombinant Form of Pneumolysin Protein from Streptococcus pneumoniae
Published in Bulletin of experimental biology and medicine (01-04-2023)“…A recombinant form of pneumolysin from Streptococcus pneumoniae was obtained. By using Vector NTI Advance 11.0 bioinformatic analysis software, specific…”
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Recombinant Pneumolysin of Pneumococci Induces TLR4 Expression and Maturation of Dendritic Cells In Vitro
Published in Bulletin of experimental biology and medicine (01-12-2023)“…Pneumolysin (Ply) is a target for the development of serotype-independent pneumococcal vaccines, an important condition for the efficacy of which is their…”
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Vaccination with virus-like particles containing hemagglutinin protects the lungs of mice with postifluenza bacterial pneumonia: virological, microbiological and clinical data
Published in Voprosy virusologiĭ (22-07-2020)“…Introduction. Influenza is a severe viral disease, a frequent complication of which is a secondary bacterial pneumonia. Influenza vaccines prevent secondary…”
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MICROBIOCENOSIS, IMMUNE SYSTEM AND HEREDITY
Published in Žurnal mikrobiologii, ėpidemiologii i immunobiologii (28-04-2017)“…The formation of pro-/eukaryotic systems is the general biological mechanism of formation and variability of the phenotype of plants, animals, human beings…”
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PROFILES OF CYTOKINES IN MICE DURING IMMUNIZATION WITH ADTP- VACCINE WITH ACELLULAR PERTUSSIS COMPONENT
Published in Žurnal mikrobiologii, ėpidemiologii i immunobiologii (01-11-2016)“…Study cytokine status in mice immunized with vaccines containing acellular pertussis component. Vaccines developed in Mechnikov RIVS - acellular pertussis…”
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A Bioplastic Material Based on Ion-Track Wound Dressings and Chitosan Nano-Scaffold
Published in Applied biochemistry and microbiology (01-12-2022)“…A bioplastic material based on a titanium-metallized ion-track wound coating and a chitosan nanoscaffold has been created, which has high strength and…”
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Quantitative Assay of B. pertussis Lipopolysaccharide
Published in Bulletin of experimental biology and medicine (01-04-2022)“…We studied activity of Bordetella pertussis LPS in the LAL test. The mean activity of various series of LPS preparations obtained from B. pertussis cells…”
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DISBIOSIS CORRECTION - THE BASIS OF REGENERATIVE MEDICINE
Published in Žurnal mikrobiologii, ėpidemiologii i immunobiologii (28-10-2018)“…The effectiveness of regeneration is provided by normal over exchange and regulatory responses, so the regenerative therapy should be directed at identifying…”
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Effect of antiviral siRNAs on the production of cytokines in vitro
Published in Tonkie himičeskie tehnologii (Online) (20-11-2022)“…Objectives . To evaluate the dynamics of the expression level of IL-1β and IL-28β (IFN-λ3) genes as a result of complex knockdown of some cellular genes, whose…”
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The study of neuraminidase immunity in protection against secondary bacterial pneumonia induced by S. aureus after influenza infection in mice
Published in Žurnal mikrobiologii, ėpidemiologii i immunobiologii (20-01-2021)“…Introduction. Pneumonia often occurs secondary to influenza infection and accounts for a large proportion of the morbidity and mortality associated with…”
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Knockdown of FLT4, Nup98, and Nup205 cellular genes as a suppressor for the viral activity of Influenza A/WSN/33 (H1N1) in A549 cell culture
Published in Tonkie himičeskie tehnologii (Online) (27-01-2022)“…Objectives. To evaluate the effect of cellular genes FLT4, Nup98, and Nup205 on the reproduction of the influenza A virus in A549 human lung cancer cell line…”
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Investigation of the anti-influenza activity of siRNA complexes against the cellular genes FLT4, Nup98, and Nup205 in vitro
Published in Tonkie himičeskie tehnologii (Online) (01-06-2022)“…Objectives. Evaluation of changes in the viral activity of influenza A/WSN/33 after complex knockdown of combinations of cellular genes FLT4, Nup98 and Nup205…”
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The safety of attenuated and recombinant nasal influenza vaccines in terms of the development of secondary bacterial superinfection
Published in Žurnal mikrobiologii, ėpidemiologii i immunobiologii (13-12-2019)“…Introduction. Influenza is a severe viral disease. The most common post-influenza complication is pneumonia. Earlier, we developed an experimental mouse model…”
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PRECLINICAL STUDIES OF RECOMBINANT PSEUDOMONAS VACCINE
Published in Žurnal mikrobiologii, ėpidemiologii i immunobiologii (28-12-2018)“…Aim. Evaluation of the efficacy and safety of the three experimental lots of Recombinant Pseudomonas Vaccine. Materials and methods. The preparation contained…”
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A role of oropharyngeal microbiota in developing acute and chronic diseases of the upper respiratory tract
Published in Infekt͡s︡ii͡a︡ i immunitet (01-05-2020)“…Currently, a rise in incidence of polyethological inflammation of the upper respiratory tract mucosa paralleled by altered resident and transient microbiota…”
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INDUCTION OF SECONDARY BACTERIAL PNEUMONIA IN MICE INFECTED WITH PANDEMIC AND LABORATORY STRAINS OF THE H1N1 INFLUENZA VIRUS
Published in Žurnal mikrobiologii, ėpidemiologii i immunobiologii (01-08-2019)“…Aim. In this study we developed and characterized a mouse model of secondary S. aureus and S. pneumoniae pneumonia following influenza virus infection with…”
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The use of biotinylated oligosaccharides related to fragments of capsular polysaccharides from Streptococcus pneumoniae serotypes 3 and 14 as a tool for assessment of the level of vaccine-induced antibody response to neoglycoconjugates
Published in Russian chemical bulletin (01-06-2016)“…In this report, the data are presented on the use of synthetic biotinylated oligosaccharides corresponding to different fragments of capsular polysaccharides…”
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