Search Results - "Poczatek, J Collin"
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Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia
Published in Nature (London) (26-01-2012)“…Multi-isotope imaging mass spectrometry is used to quantify protein turnover in animal stereocilia, showing that rapid turnover occurs only in stereocilia…”
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Antidepressant treatment effects on hippocampal protein turnover: Molecular and spatial insights from mass spectrometry
Published in Proteomics (Weinheim) (01-06-2022)“…A major challenge in managing depression is that antidepressant drugs take a long time to exert their therapeutic effects. For the development of faster‐acting…”
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Segmentation of multi-isotope imaging mass spectrometry data for semi-automatic detection of regions of interest
Published in PloS one (09-02-2012)“…Multi-isotope imaging mass spectrometry (MIMS) associates secondary ion mass spectrometry (SIMS) with detection of several atomic masses, the use of stable…”
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3D multi-isotope imaging mass spectrometry reveals penetration of 18O-trehalose in mouse sperm nucleus
Published in PloS one (2012)“…The prevalence of genetically engineered mice in medical research has led to ever increasing storage costs. Trehalose has a significant beneficial effect in…”
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Quantitative imaging of deuterated metabolic tracers in biological tissues with nanoscale secondary ion mass spectrometry
Published in International journal of mass spectrometry (01-11-2017)“…[Display omitted] •Measurement of deuterated tracers in biological tissues with NanoSIMS.•C2D polyatomic species is used as a proxy for native…”
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Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia
Published in Nature (London) (26-01-2012)“…Hair cells of the inner ear are not normally replaced during an animal's life, and must continually renew components of their various organelles (1). Among…”
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