Search Results - "Pnina Scherzer"
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Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy
Published in Journal of lipid research (01-03-2014)“…Animal models link ectopic lipid accumulation to renal dysfunction, but whether this process occurs in the human kidney is uncertain. To this end, we…”
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The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria
Published in American journal of physiology. Renal physiology (01-12-2009)“…Diet-induced obesity is associated with proteinuria and glomerular disease in humans and rodents. We have shown that in mice fed a high-fat diet, increased…”
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Diabetic Nephropathy Is Accelerated by Farnesoid X Receptor Deficiency and Inhibited by Farnesoid X Receptor Activation in a Type 1 Diabetes Model
Published in Diabetes (New York, N.Y.) (01-11-2010)“…The pathogenesis of diabetic nephropathy is complex and involves activation of multiple pathways leading to kidney damage. An important role for altered lipid…”
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Farnesoid X Receptor Modulates Renal Lipid Metabolism, Fibrosis, and Diabetic Nephropathy
Published in Diabetes (New York, N.Y.) (01-10-2007)“…Farnesoid X Receptor Modulates Renal Lipid Metabolism, Fibrosis, and Diabetic Nephropathy Tao Jiang 1 , Xiaoxin X. Wang 1 , Pnina Scherzer 2 , Paul Wilson 1 ,…”
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Psammomys obesus, a particularly important animal model for the study of the human diabetic nephropathy
Published in Anatomy & cell biology (01-09-2011)“…The Psammomys obesus lives in natural desert habitat on low energy (LE) diet, however when maintained in laboratory conditions with high energy (HE) diet it…”
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Psammomys obesus, a particularly important animal model for the study of the human diabetic nephropathy
Published in Anatomy & cell biology (30-09-2011)Get full text
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Sodium‐pump gene‐expression, protein abundance and enzyme activity in isolated nephron segments of the aging rat kidney
Published in Physiological reports (01-06-2015)“…Aging is associated with alteration in renal tubular functions, including sodium handling and concentrating ability. Na‐K‐ATPase plays a key role in driving…”
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Pancreatic acinar and islet cell infection by low-dose SV40 administration
Published in Pancreas (01-05-2008)“…Viral vector uptake into the pancreas is rare. The few viral vectors reported to transduce in vivo pancreatic islets after systemic injection required…”
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Indomethacin and sodium retention in the rat: role of inhibition of prostaglandin E2 synthesis
Published in Clinical science (1979) (01-09-1992)“…1. To further explore the Na(+)-retaining effect of indomethacin along the whole length of the nephron, the Na(+)-K(+)-ATPase activity of isolated tubules from…”
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Na,K-ATPase in Isolated Nephron Segments in Rats With Experimental Heart Failure
Published in Circulation research (01-04-1991)“…To characterize renal transport of Na in heart failure, urinary Na excretion (UNaV), aldosterone levels, and Na,K-ATPase activity in isolated nephron segments…”
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Effect of indomethacin in vivo and PGE2 in vitro on MTAL Na-K-ATPase of the rat kidney
Published in Pflügers Archiv (01-02-1990)“…We have previously shown that prostaglandin synthesis inhibition in rats which reduces urinary excretion of PGE2 and sodium, is associated with increased…”
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Reduced Na-K-ATPase in distal nephron in glycerol-induced acute tubular necrosis
Published in Kidney international (01-03-1990)“…Reduced Na-K-ATPase in distal nephron in glycerol-induced acute tubular necrosis. To further characterize changes in tubular Na-K-ATPase in acute tubular…”
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