Search Results - "Plzak, Jan"
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Glutamine and serum starvation alters the ATP production, oxidative stress, and abundance of mitochondrial RNAs in extracellular vesicles produced by cancer cells
Published in Scientific reports (28-10-2024)“…Induction of autophagy represents an effective survival strategy for nutrient-deprived or stressed cancer cells. Autophagy contributes to the modulation of…”
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2
The Head and Neck Squamous Cell Carcinoma Microenvironment as a Potential Target for Cancer Therapy
Published in Cancers (28-03-2019)“…Similarly to other types of malignant tumours, the incidence of head and neck cancer is increasing globally. It is frequently associated with smoking and…”
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3
Cancer Microenvironment: What Can We Learn from the Stem Cell Niche
Published in International Journal of Molecular Sciences (12-10-2015)“…Epidermal stem cells (ESCs) are crucial for maintenance and self- renewal of skin epithelium and also for regular hair cycling. Their role in wound healing is…”
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4
Experience with follow-up strategy in selected patients with Warthin tumour diagnosed by ultrasound-guided fine-needle aspiration biopsy (FNAB)
Published in European archives of oto-rhino-laryngology (01-04-2022)“…Purpose Warthin tumour (WT) management options comprise surgery or follow-up. The purpose of this study was to asses our experience with the follow-up strategy…”
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5
Sensitivity to Cisplatin in Head and Neck Cancer Cells Is Significantly Affected by Patient-Derived Cancer-Associated Fibroblasts
Published in International journal of molecular sciences (15-02-2021)“…Cancer-associated fibroblasts (CAFs) are one of the most abundant and critical components of the tumor stroma. CAFs can impact many important steps of…”
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6
Hemihypoglossal–facial nerve anastomosis: results and electromyographic characterization
Published in European archives of oto-rhino-laryngology (2022)“…Introduction The facial nerve surgery belongs to the basic procedures during lateral skull base approaches. Its damage has serious medical and psychological…”
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7
Smooth muscle actin-expressing stromal fibroblasts in head and neck squamous cell carcinoma: Increased expression of galectin-1 and induction of poor prognosis factors
Published in International journal of cancer (01-12-2012)“…Tumor stroma is an active part influencing the biological properties of malignancies via molecular cross‐talk. Cancer‐associated fibroblasts play a significant…”
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8
Psychophysical Olfactory Tests and Detection of COVID-19 in Patients With Sudden Onset Olfactory Dysfunction: A Prospective Study
Published in Ear, nose, & throat journal (01-11-2020)“…Objective: To investigate the coronavirus disease 2019 (COVID-19) status of patients with initial sudden olfactory anosmia (ISOA) through nasopharyngeal swabs…”
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Utility of fine-needle aspiration biopsy (FNAB) in parotid pleomorphic adenoma diagnosis and management
Published in Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia (01-06-2024)“…Pleomorphic adenoma (PA), the most common benign tumour of the parotid gland, requires accurate preoperative diagnosis owing to its capacity for malignant…”
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10
The Role of Narrow Band Imaging in the Detection of Recurrent Laryngeal and Hypopharyngeal Cancer after Curative Radiotherapy
Published in BioMed research international (01-01-2014)“…Narrow band imaging is considered a significant improvement in the possibility of detecting early mucosal lesion of the upper aerodigestive tract. Early…”
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11
The comparison between intratympanic gentamicin prehabilitation and postoperative virtual reality exposure to standard vestibular training in patients with vestibular schwannoma
Published in European archives of oto-rhino-laryngology (10-08-2024)“…Resection of the vestibular schwannoma causes acute peripheral vestibular loss. The process of central compensation starts immediately afterward. The…”
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12
The expression profiles of CD47 in the tumor microenvironment of salivary gland cancers: a next step in histology-driven immunotherapy
Published in BMC cancer (28-09-2022)“…Abstract Background Salivary gland carcinomas (SGC) are extremely rare malignancies with only limited treatment options for the metastatic phase of the…”
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13
Text-to-speech synthesis as an alternative communication means after total laryngectomy
Published in Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia (01-06-2021)“…Total laryngectomy still plays an essential part in the treatment of laryngeal cancer and loss of voice is the most feared consequence of the surgery. Commonly…”
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14
Low-grade fibromyxoid sarcoma of the maxillary sinus
Published in Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia (01-09-2021)“…Low-grade fibromyxoid sarcoma (LGFMS) is a rare malignant tumor. Moreover, only 3 cases of LGFMS originating from the nasal cavity and/or paranasal sinuses…”
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15
High incidence of occult familial SDHD cases amongst Czech patients with head and neck paragangliomas
Published in Frontiers in endocrinology (Lausanne) (2023)“…Head and neck paragangliomas (HNPGLs) are rare neuroendocrine tumors, which are mostly benign in nature. Amongst all genes, Succinate Dehydrogenase Subunit D (…”
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mRNA Subtype of Cancer-Associated Fibroblasts Significantly Affects Key Characteristics of Head and Neck Cancer Cells
Published in Cancers (03-05-2022)“…Head and neck squamous cell carcinomas (HNSCC) belong among severe and highly complex malignant diseases showing a high level of heterogeneity and consequently…”
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The Role of NBI HDTV Magnifying Endoscopy in the Prehistologic Diagnosis of Laryngeal Papillomatosis and Spinocellular Cancer
Published in BioMed research international (01-01-2014)“…Narrow band imaging (NBI) HDTV (high definition television) magnifying endoscopy is considered to be superior for the accurate display of the microvascular…”
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18
Moderate sensorineural hearing loss is typical for DFNB16 caused by various types of mutations affecting the STRC gene
Published in European archives of oto-rhino-laryngology (01-12-2019)“…Introduction Hearing loss is the most frequent sensory disorder and is genetically extremely heterogeneous. By far the most frequent cause of nonsyndromic…”
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Upregulation of IL-6, IL-8 and CXCL-1 production in dermal fibroblasts by normal/malignant epithelial cells in vitro: Immunohistochemical and transcriptomic analyses
Published in Biology of the cell (01-12-2012)“…Background information Considering an analogy between wound healing and tumour progression, we studied chemokine and cytokine transcription and expression in…”
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Analysis of HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas and Paired Normal Mucosae Reveals Cyclin D1 Deregulation and Compensatory Effect of Cyclin D2
Published in Cancers (26-03-2020)“…Aberrant regulation of the cell cycle is a typical feature of all forms of cancer. In head and neck squamous cell carcinoma (HNSCC), it is often associated…”
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