Search Results - "Plunkett, R. J."

The impact of age and sex on the incidence of glial tumors in New York state from 1976 to 1995 by MCKINLEY, Brian P, MICHALEK, Arthur M, FENSTERMAKER, Robert A, PLUNKETT, Robert J

“…In this study the authors describe secular trends in the incidence of three glial tumors--glioblastoma multiforme (GBM), astrocytoma not otherwise specified…”
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Neural Stem Cell Detection, Characterization, and Age-Related Changes in the Subventricular Zone of Mice by Maslov, Alexander Y, Barone, Tara A, Plunkett, Robert J, Pruitt, Steven C

“…The mammalian brain contains neural stem cells (NSCs) that allow continued neurogenesis throughout the life of the animal. However, neurogenesis is known to…”
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Hormonal effects on glioblastoma multiforme in the nude rat model by PLUNKETT, R. J, LIS, A, BARONE, T. A, FRONCKOWIAK, M. D, GREENBERG, S. J

“…The authors studied the effect of gender and hormonal status on survival in nude rats implanted with human glioblastoma multiforme (GBM) cell lines. Nude rats…”
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Intrastriatal implantation of interleukin-1 : reduction of parkinsonism in rats by enhancing neuronal sprouting from residual dopaminergic neurons in the ventral tegmental area of the midbrain by JIN WANG, BANKIEWICZ, K. S, PLUNKETT, R. J, OLDFIELD, E. H

“…Intrastriatal implantation with dopaminergic of nondopaminergic tissue can elicit behavioral recovery in parkinsonian animals. Because in these animals,…”
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Syngeneic central nervous system transplantation of genetically transduced mature, adult astrocytes by SELKIRK, S. M, GREENBERG, S. J, PLUNKETT, R. J, BARONE, T. A, LIS, A, SPENCE, P. O

“…Advances in the development of highly infectious, replication-deficient recombinant retroviruses provide an efficient means of stable transfer of gene…”
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The effect of fetal mesencephalon implants on primate MPTP-induced parkinsonism. Histochemical and behavioral studies by Bankiewicz, K S, Plunkett, R J, Jacobowitz, D M, Porrino, L, di Porzio, U, London, W T, Kopin, I J, Oldfield, E H

“…Parkinsonism or hemiparkinsonism was induced by administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in four rhesus monkeys, which then…”
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Long-term evaluation of hemiparkinsonian monkeys after adrenal autografting or cavitation alone by PLUNKETT, R. J, BANKIEWICZ, K. S, CUMMINS, A. C, MILETICH, R. S, SCHWARTZ, J. P, OLDFIELD, E. H

“…Autografts of adrenal medulla were implanted into preformed cavities in the caudate nuclei of four rhesus monkeys with hemiparkinsonism induced by…”
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Fetal nondopaminergic neural implants in parkinsonian primates : histochemical and behavioral studies by BANKIEWICZ, K. S, PLUNKETT, R. J, JACOBOWITZ, D. M, KOPIN, I. J, OLDFIELD, E. H

“…Implantation of fetal dopamine-containing tissue into preformed cavities in the caudate nucleus of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced…”
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Intratumoral hemorrhage after remote subtotal microsurgical resection and gamma knife radiosurgery for vestibular schwannoma by Karampelas, I, Alberico, R A, Plunkett, R J, Fenstermaker, R A

“…Our report describes the occurrence of intratumoral hemorrhage in a vestibular schwannoma, which was treated with microsurgical resection thirteen years and…”
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Subthalamic nucleus metastasis causing hemichorea-hemiballism treated by gamma knife stereotactic radiosurgery by Karampelas, I., Podgorsak, M. B., Plunkett, R. J., Fenstermaker, R. A.

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Reversal of hemiparkinsonian syndrome in nonhuman primates by amnion implantation into caudate nucleus by Bankiewicz, K S, Palmatier, M, Plunkett, R J, Cummins, A, Oldfield, E H

“…Although recent animal and human experiments suggest that tissue implantation can ameliorate parkinsonism, there is controversy about what mechanism underlies…”
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Long-term production of neurotrophic factors by astrocyte cultures from hemiparkinsonian rat brain by Langan, T J, Plunkett, R J, Asada, H, Kelly, K, Kaseloo, P

“…Transplantation of dopaminergic or neurotrophic tissues is an experimental treatment of Parkinson's Disease. However, in animal models sustained recovery may…”
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Intratumoral infusion of topotecan prolongs survival in the nude rat intracranial U87 human glioma model by POLLINA, J, PLUNKETT, R. J, CIESIELSKI, M. J, LIS, A, BARONE, T. A, GREENBERG, S. J, FENSTERMAKER, R. A

“…Topotecan is a topoisomerase (topo) I inhibitor with promising activity in preclinical studies. We hypothesized that low-dose intratumoral delivery of…”
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Traumatized rat striatum produces neurite-promoting and neurotrophic activities in vitro by ASADA, H, KASELOO, P. A, LIS, A, PETTI, D. M, PLUNKETT, R. J

“…We have previously reported that ciliary neurotrophic factor (CNTF) mRNA is upregulated in the rat striatum following trauma and that its peak is coincident…”
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MRI detects acute degeneration of the nigrostriatal dopamine system after MPTP exposure in hemiparkinsonian monkeys by Miletich, R S, Bankiewicz, K S, Quarantelli, M, Plunkett, R J, Frank, J, Kopin, I J, Di Chiro, G

“…Exposure to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) can cause an acute chemical toxicity resulting in a parkinsonian state in humans and nonhuman…”
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Trauma-induced striatal CNTF and BDNF mRNA in hemiparkinsonian rats by Plunkett, Robert J, Ip, Nancy Y, Asada, Hideo, Friedman, Beth, Pan, Li, Kaseloo, Paul A, Parfitt, Margaret M

“…SURGICAL implantation of tissues into the brain causes trauma to the region receiving the graft. This study shows that real or simulated striatal trauma in…”
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Transient behavioral recovery in hemiparkinsonian primates after adrenal medullary allografts by Bankiewicz, K S, Plunkett, R J, Kophin, I J, Jacobowitz, D M, London, W T, Oldfield, E H

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Pleiotropic expression of heterologous cytokine/receptor genes in HTLV-1 associated diseases : Candidate TRS for chimeric gene therapy by GREENBERG, S. J, CHOI, U, OVERTURF, P. M, GLENISTER, N, ROBINSON, T. A, LIS, A, HOHMANN, P, GOLDMAN, B. D, OSEROFF, A. R, PLUNKETT, R. J

“…DNA motifs that encode for specific transcriptional regulatory sequences (TRS) when engineered adjacent to the structural protein coding domain of a suicide…”
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In vitro assessment of neurotrophic activity from the striatum of aging rats by Kaseloo, Paul A., Lis, Agnieszka, Asada, Hideo, Barone, Tara A., Plunkett, Robert J.

“…Neurotrophic factors are produced in the striatum following trauma and have a demonstrable effect on in vitro bioassays and on in vivo graft survival. We have…”
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2-Methoxyestradiol inhibits proliferation of normal and neoplastic glial cells, and induces cell death, in vitro by Lis, Agnieszka, Ciesielski, Michael J., Barone, Tara A., Scott, Bryan E., Fenstermaker, Robert A., Plunkett, Robert J.

“…2-Methoxyestradiol (2ME), a metabolite of estradiol (E), inhibits proliferation of various tumor cells. In this study we determined the effect of 2ME on human…”
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