Search Results - "Plum, Laura M."
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The essential toxin: impact of zinc on human health
Published in International journal of environmental research and public health (01-04-2010)“…Compared to several other metal ions with similar chemical properties, zinc is relatively harmless. Only exposure to high doses has toxic effects, making acute…”
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Zinc signals promote IL‐2‐dependent proliferation of T cells
Published in European journal of immunology (01-05-2010)“…Zinc signals, i.e. a change of the intracellular concentration of free zinc ions in response to receptor stimulation, are involved in signal transduction in…”
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Characterization of the first-in-class T-cell-engaging bispecific single-chain antibody for targeted immunotherapy of solid tumors expressing the oncofetal protein claudin 6
Published in Oncoimmunology (03-03-2016)“…The fetal tight junction molecule claudin 6 (CLDN6) is virtually absent from any normal tissue, whereas it is aberrantly and frequently expressed in various…”
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Impact of lead and mercuric ions on the interleukin-2-dependent proliferation and survival of T cells
Published in Archives of toxicology (01-02-2013)“…Mercury and lead are widespread in the environment, causing chronic exposure of a large population to low concentrations of these metals. While several studies…”
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Impact of allicin on macrophage activity
Published in Food chemistry (01-09-2012)“…► Allicin showed comparable toxicity toward Escherichia coli and Raw 264.7 murine macrophages. ► In Raw 264.7, allicin inhibits NO production, but not…”
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Peptide microarrays enable rapid mimotope optimization for pharmacokinetic analysis of the novel therapeutic antibody IMAB362
Published in Biotechnology journal (01-04-2014)“…As membrane proteins play an important role in a variety of life‐threatening diseases, the development of therapeutic monoclonal antibodies against membrane…”
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