Search Results - "Plug, Annemieke"

Delayed Replication Timing Leads to Delayed Mitotic Chromosome Condensation and Chromosomal Instability of Chromosome Translocations by Smith, Leslie, Plug, Annemieke, Thayer, Mathew

“…Chromosomal rearrangements are found in virtually all types of human cancers. We show that certain chromosome translocations display a delay in mitotic…”
Get full text

Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis by Baker, Sean M, Bronner, C.Eric, Zhang, Lin, Plug, Annemieke W, Robatzek, Merrilee, Warren, Gwynedd, Elliott, Eileen A, Yu, Jian, Ashley, Terry, Arnheim, Norman, Flavell, Richard A, Liskay, R.Michael

“…Using gene targeting in embryonic stem cells, we have derived mice with a null mutation in a DNA mismatch repair gene homolog, PMS2. We observed microsatellite…”
Get full text

Bloom's Syndrome Protein, BLM, Colocalizes with Replication Protein A in Meiotic Prophase Nuclei of Mammalian Spermatocytes by Walpita, Deepika, Plug, Annemieke W., Neff, Norma F., German, James, Ashley, Terry

“…Bloom's syndrome (BS) is a rare autosomal recessive disorder of humans characterized by severe pre- and postnatal growth deficiency, immunodeficiency, genomic…”
Get full text

Evidence for a Role for DNA Polymerase β in Mammalian Meiosis by Plug, Annemieke W., Clairmont, Caroline A., Sapi, Eva, Ashley, Terry, Sweasy, Joann B.

“…DNA polymerase β (pl β ) is an enzyme possessing both polymerase and deoxyribose phophatase activities. Although pol β is not believed to participate in the…”
Get full text

Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over by Baker, Sean M, Plug, Annemieke W, Prolla, Tomas A, Bronner, C. Eric, Harris, Allie C, Yao, Xiang, Christie, Donna-Marie, Monell, Craig, Arnheim, Norm, Bradley, Allan, Ashley, Terry, Liskay, R. Michael

Get full text

ATM and RPA in meiotic chromosome synapsis and recombination by Plug, Annemieke W, Peters, Antoine H.F.M, Xu, Yang, Keegan, Kathleen S, Hoekstra, Merl F, Baltimore, David, Boer, Peter de, Ashley, Terry

“…ATM is a member of the phosphatidylinositol 3-kinase (PIK)-like kinases, some of which are active in regulating DNA damage-induced mitotic cell-cycle…”
Get full text

Mammalian Ubiquitin-Conjugating Enzyme Ubc9 Interacts with Rad51 Recombination Protein and Localizes in Synaptonemal Complexes by Kovalenko, Oleg V., Plug, Annemieke W., Haaf, Thomas, Gonda, David K., Ashley, Terry, Ward, David C., Radding, Charles M., Golub, Efim I.

“…Hsubc9, a human gene encoding a ubiquitinconjugating enzyme, has been cloned. The 18-kDa HsUbc9 protein is homologous to the ubiquitin-conjugating enzymes Hus5…”
Get full text

Presynaptic Association of Rad51 Protein with Selected Sites in Meiotic Chromatin by Plug, Annemieke W., Xu, Jihong, Reddy, Gurucharan, Golub, Efim I., Ashley, Terry

“…Eukaryotic homologs of Escherichia coli RecA protein have been shown to form nucleoprotein filaments with single-stranded DNA that recognize homologous…”
Get full text

Changes in protein composition of meiotic nodules during mammalian meiosis by Plug, A W, Peters, A H, Keegan, K S, Hoekstra, M F, de Boer, P, Ashley, T

“…Homologous chromosome synapsis and meiotic recombination are facilitated by several meiosis-specific structures: the synaptonemal complex (SC), and two types…”
Get full text

Dynamic changes in Rad51 distribution on chromatin during meiosis in male and female vertebrates by Ashley, T, Plug, A W, Xu, J, Solari, A J, Reddy, G, Golub, E I, Ward, D C

“…Antibodies against human Rad51 protein were used to examine the distribution of Rad51 on meiotic chromatin in mouse spermatocytes and oocytes as well as…”
Get full text

Telomere erosion and chromosomal instability in cells expressing the HPV oncogene 16E6 by PLUG-DEMAGGIO, Annemieke W, SUNDSVOLD, Terri, WURSCHER, Michelle A, KOOP, Jennifer I, KLINGELHUTZ, Aloysius J, MCDOUGALL, James K

“…Progression to advanced-stage cervical carcinomas is characterized by a recurrent pattern of chromosomal rearrangements. Structural chromosome rearrangements…”
Get full text

Meiosis in carriers of heteromorphic bivalents: sex differences and implications for male fertility by Peters, A H, Plug, A W, de Boer, P

“…Mice that are double heterozygous for the semi-identical T(1;13)70H and T(1;13)1Wa reciprocal translocations display a great variation in male fertility. The…”
Get full text

Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells by Scully, Ralph, Chen, Junjie, Plug, Annemieke, Xiao, Yonghong, Weaver, David, Feunteun, Jean, Ashley, Terry, Livingston, David M

“…BRCA1 immunostaining reveals discrete, nuclear foci during S phase of the cell cycle. Human Rad51, a homolog of bacterial RecA, behaves similarly. The two…”
Get full text

The human papillomavirus type 16 E6 oncogene induces premature mitotic chromosome segregation by Plug-Demaggio, Annemieke W, McDougall, James K

“…Expression of the human papillomavirus type 16 E6 and E7 oncogenes initiates and maintains abnormal cell replication, by interacting with the p53 and…”
Get full text

The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes by Keegan, K S, Holtzman, D A, Plug, A W, Christenson, E R, Brainerd, E E, Flaggs, G, Bentley, N J, Taylor, E M, Meyn, M S, Moss, S B, Carr, A M, Ashley, T, Hoekstra, M F

“…A number of cell-cycle checkpoint genes have been shown to play important roles in meiosis. We have characterized the human and mouse counterpart of the…”
Get full text

Persistent Alterations in Regional Brain Glial Fibrillary Acidic Protein and Synaptophysin Levels Following Pre- and Postnatal Polychlorinated Biphenyl Exposure by Morse, Dennis C., Plug, Annemieke, Wesseling, Wendelien, van den Berg, Kor J., Brouwer, Abraham

“…Pregnant Wistar WU rats were exposed to 0, 5, and 25 mg of the commercial polychlorinated biphenyl (PCB) mixture Aroclor 1254 per kilogram of body weight on…”
Get full text

A drying-down technique for the spreading of mammalian meiocytes from the male and female germline by Peters, A H, Plug, A W, van Vugt, M J, de Boer, P

Get full text

SHORT COMMUNICATIONS A drying-down technique for the spreading of mammalian meiocytes from the male and female germline by Peters, Antoine Hfm, Plug, Annemieke W, van Vugt, Martine J, de Boer, Peter

Get full text