Search Results - "Plourde, Gary W"

A Direct and Stereocontrolled Route to Conjugated Enediynes by Jones, Graham B, Wright, Justin M, Plourde, Gary W, Hynd, George, Huber, Robert S, Mathews, Jude E

“…A unified synthetic route to 3-hex-en-1,5-diynes, a key building block found in many of the enediyne antitumor agents and designed materials, was developed…”
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Halo-Enediynes:  Probing the Electronic and Stereoelectronic Contributions to the Bergman Cycloaromatization by Plourde, Gary W, Warner, Philip M, Parrish, Dennis A, Jones, Graham B

“…A series of halogen-substituted cyclic enediynes were prepared with use of carbenoid coupling strategy. DFT analysis, initially used to identify synthesis…”
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Facile Unmasking of Dicobalt Hexacarbonyl Complexes of 1-Cyclodecene-3,9-diynes (Enediynes) by Jones, Graham B, Wright, Justin M, Rush, Teresa M, Plourde, Gary W, Kelton, Thomas F, Mathews, Jude E, Huber, Robert S, Davidson, James P

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Target-Directed Enediynes:  Designed Estramycins by Jones, Graham B, Hynd, George, Wright, Justin M, Purohit, Ajay, Plourde, Gary W, Huber, Robert S, Mathews, Jude E, Li, Aiwen, Kilgore, Michael W, Bubley, Glenn J, Yancisin, Molly, Brown, Myles A

“…The goal of selective targeting of enediyne cytotoxins has been investigated using estrogenic delivery vehicles. A series of estrogen−enediyne conjugates were…”
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Electronic Control of the Bergman Cycloaromatization:  Synthesis and Chemistry of Chloroenediynes by Jones, Graham B, Plourde, Gary W

“…A series of cyclic mono- and dichloroenediynes have been prepared using an intramolecular carbenoid coupling reaction. The halogen atom had a retardative…”
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Understanding Enediyne−Protein Interactions:  Diyl Atom Transfer Results in Generation of Aminoacyl Radicals by Jones, Graham B, Plourde, Gary W, Wright, Justin M

“…The origin of the protein modulating capacity of enediynes has been probed. A series of synthetic enediyne-derived diyls participated in atom transfer…”
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Stereoselective access to substituted enediyne building blocks by Hynd, George, Jones, Graham B., Plourde, Gary W., Wright, Justin M.

“…Intermolecular coupling-elimination of disubstituted propargyl bromides gives rise to differentiallysubstituted 3-hexen-1,5-diynes with E:Z selectivity as high…”
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