The method of activation of animal cells cultures in vitro for the reproduction of viruses

The level of type 1 (IBR) herpesvirus enrichment and parainfluenza-3 (PIV-3) virus in the MDBK cell culture, containing chitosan as a stimulating activator, exceeded target values by 1.9 and 1.20 respectively. [...]the introduction of apisan into the growth promotion medium of natural biopolymer - a...

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Bibliographic Details
Published in:Journal of pharmaceutical sciences and research Vol. 11; no. 2; pp. 562 - 565
Main Authors: Plotnikova, Edie M, Nizamov, Ramzi N, Gaffarov, Kharis Z, Churina, Zoya G, Samsonov, Andrey I, Arkharova, Irina A, Gumerov, Vali G
Format: Journal Article
Language:English
Published: Cuddalore Journal of Pharmaceutical Sciences and Research 01-02-2019
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Summary:The level of type 1 (IBR) herpesvirus enrichment and parainfluenza-3 (PIV-3) virus in the MDBK cell culture, containing chitosan as a stimulating activator, exceeded target values by 1.9 and 1.20 respectively. [...]the introduction of apisan into the growth promotion medium of natural biopolymer - apisan stimulates the proliferation growth and sensitivity of cell culture to the test viruses and their reproduction level. [...]of a large body of research, antioxidant, antibacterial, antiviral, regenerating, immune stimulating, antitoxic and some other factors of chitosan have been discovered [4]. According to Japanese researchers, chitosan is the substance of the 21st century [5]. [...]the introduction of apisan into the growth medium cultivation with cultures of animals' cells leads to the significant increase (by 3 times) of cells proliferating activity and allows avoiding the use of deficient components - growth factors.
ISSN:0975-1459