Search Results - "Pliss, Artem"
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Tunable Narrow Band Emissions from Dye-Sensitized Core/Shell/Shell Nanocrystals in the Second Near-Infrared Biological Window
Published in Journal of the American Chemical Society (21-12-2016)“…We introduce a hybrid organic–inorganic system consisting of epitaxial NaYF4:Yb3+/X3+@NaYbF4@NaYF4:Nd3+ (X = null, Er, Ho, Tm, or Pr) core/shell/shell (CSS)…”
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Chromosome territories and the global regulation of the genome
Published in Genes chromosomes & cancer (01-07-2019)“…Spatial positioning is a fundamental principle governing nuclear processes. Chromatin is organized as a hierarchy from nucleosomes to Mbp chromatin domains…”
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IDH1 mutations induce organelle defects via dysregulated phospholipids
Published in Nature communications (27-01-2021)“…Infiltrating gliomas are devastating and incurable tumors. Amongst all gliomas, those harboring a mutation in isocitrate dehydrogenase 1 mutation (IDH1 mut )…”
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Cycles of protein condensation and discharge in nuclear organelles studied by fluorescence lifetime imaging
Published in Nature communications (28-01-2019)“…Nuclear organelles are viscous droplets, created by concentration-dependent condensation and liquid–liquid phase separation of soluble proteins. Nuclear…”
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Fluorescence lifetime imaging for studying DNA compaction and gene activities
Published in Light, science & applications (02-11-2021)“…Optical imaging is a most useful and widespread technique for the investigation of the structure and function of the cellular genomes. However, an analysis of…”
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Mitochondrial Dysfunction and Apoptosis in Brain Microvascular Endothelial Cells Following Blast Traumatic Brain Injury
Published in Cellular and molecular neurobiology (01-10-2023)“…Blood brain barrier (BBB) breakdown is a key driver of traumatic brain injury (TBI), contributing to prolonged neurological deficits and increased risk of…”
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Changes in Biomolecular Profile in a Single Nucleolus during Cell Fixation
Published in Analytical chemistry (Washington) (04-11-2014)“…Fixation of biological sample is an essential technique applied in order to “freeze” in time the intracellular molecular content. However, fixation induces…”
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Macromolecular Profiling of Organelles in Normal Diploid and Cancer Cells
Published in Analytical chemistry (Washington) (17-10-2017)“…To advance an understanding of cellular regulation and function it is crucial to identify molecular contents in cellular organelles, which accommodate specific…”
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Molecular profiling of single organelles for quantitative analysis of cellular heterogeneity
Published in Scientific reports (26-07-2017)“…Recent developments in Raman spectroscopy instrumentation and data processing algorithms have led to the emergence of Ramanomics - an independent discipline…”
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Nonlinear Optical Imaging and Raman Microspectrometry of the Cell Nucleus throughout the Cell Cycle
Published in Biophysical journal (17-11-2010)“…Fundamental understanding of cellular processes at molecular level is of considerable importance in cell biology as well as in biomedical disciplines for early…”
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Fluorescence lifetime imaging of fluorescent proteins as an effective quantitative tool for noninvasive study of intracellular processes
Published in Journal of innovative optical health science (01-01-2018)“…Fluorescence lifetime imaging (FLIM) is an effective noninvasive bioanalytical tool based on measuring fluorescent lifetime of fluorophores. A growing number…”
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Unlocking nature's brilliance: using Antarctic extremophile Shewanella baltica to biosynthesize lanthanide-containing nanoparticles with optical up-conversion
Published in Journal of nanobiotechnology (18-10-2024)“…Both lanthanide-containing and fluorine-containing nanomaterials present challenging targets for microbial biosynthesis because these elements are toxic to…”
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Perfluoropolyether Nanoemulsion Encapsulating Chlorin e6 for Sonodynamic and Photodynamic Therapy of Hypoxic Tumor
Published in Nanomaterials (Basel, Switzerland) (19-10-2020)“…Sonodynamic therapy (SDT) has emerged as an important modality for cancer treatment. SDT utilizes ultrasound excitation, which overcomes the limitations of…”
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Applications of fluorescence lifetime imaging in clinical medicine
Published in Journal of innovative optical health science (01-01-2018)“…Fluorescence lifetime is not only associated with the molecular structure of fluorophores, but also strongly depends on the environment around them, which…”
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Ramanomics: New Omics Disciplines Using Micro Raman Spectrometry with Biomolecular Component Analysis for Molecular Profiling of Biological Structures
Published in Biosensors (Basel) (15-11-2017)“…Modern instrumentation for Raman microspectroscopy and current techniques in analysis of spectral data provide new opportunities to study molecular…”
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BCAbox Algorithm Expands Capabilities of Raman Microscope for Single Organelles Assessment
Published in Biosensors (Basel) (10-11-2018)“…Raman microspectroscopy is a rapidly developing technique, which has an unparalleled potential for in situ proteomics, lipidomics, and metabolomics, due to its…”
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Biophotonic probing of macromolecular transformations during apoptosis
Published in Proceedings of the National Academy of Sciences - PNAS (20-07-2010)“…We introduce here multiplex nonlinear optical imaging as a powerful tool for studying the molecular organization and its transformation in cellular processes,…”
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Synergic treatment of Alzheimer’s disease with brain targeted nanoparticles incorporating NgR-siRNA and brain derived neurotrophic factor
Published in Smart materials in medicine (2020)“…The decrease and functional failure of the central cholinergic neurons caused by degeneration and necrosis, not only directly led to a series of clinical…”
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Ladder-like amplification of the type I interferon gene cluster in the human osteosarcoma cell line MG63
Published in Chromosome research (01-12-2008)“…The organization of the type I interferon (IFN) gene cluster (9p21.3) was studied in a human osteosarcoma cell line (MG63). Array comparative genomic…”
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Small molecule based EGFR targeting of biodegradable nanoparticles containing temozolomide and Cy5 dye for greatly enhanced image-guided glioblastoma therapy
Published in Nanomedicine (01-04-2022)“…Current glioblastoma multiforme (GBM) treatment is insufficient, facing obstacles like poor tumor accumulation and dose limiting side effects of…”
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