Timing of Primary Surgery for Cleft Palate

In this randomized trial, primary surgery for isolated cleft palate at 6 months of age led to better velopharyngeal function at the age of 5 years than primary surgery at 12 months of age.

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Bibliographic Details
Published in:	The New England journal of medicine Vol. 389; no. 9; pp. 795 - 807
Main Authors:	Gamble, Carrol, Persson, Christina, Willadsen, Elisabeth, Albery, Liz, Soegaard Andersen, Helene, Zattoni Antoneli, Melissa, Appelqvist, Malin, Aukner, Ragnhild, Bodling, Pia, Bowden, Melanie, Brunnegård, Karin, Cairns, Gillian, Calladine, Samantha, Campbell, Linsay, Clayton-Smith, Jill, Cooper, Rachael, Conroy, Elizabeth, El-Angbawi, Ahmed, Kildegaard Emborg, Berit, Enfält Wikman, Josefin, Fitzpatrick, Beth, Fukushiro, Ana Paula, Guedes de Azevedo Bento Gonçalves, Cristina, Havstam, Christina, Hvistendahl, Anne Katherine, Jorgensen, Line Dahl, Klinto, Kristina, Berntsen Kvinnsland, Marit, Larham, Catriona, Lemvik, Jorunn, Leturgie, Louise, Liljerehn, Eva, Lodge, Natalie, Lohmander, Anette, McMahon, Siobhan, Mehendale, Felicity, Miguel, Haline Coracine, Moe, Marianne, Nielsen, Joan Bogh, Nyberg, Jill, Pedersen, Nina-Helen, Phippen, Ginette, Alvarez Piazentin-Penna, Silvia Helena, Patrick, Kathryn, Pliskin, Lindsay, Rigby, Lucy, Semb, Gunvor, Southby, Lucy, Sporre, Maria, Björkman Taleman, Ann-Sofie, Tangstad, Jorid, Trindade, Inge Elly Kiemle, Underwood, Imogen, van Eeden, Stephanie, Westberg, Liisi Raud, Williamson, Paula Ruth, Paciello Yamashita, Renata, Munro, Kevin, Walsh, Tanya, Shaw, William
Format:	Journal Article
Language:	English
Published:	United States Massachusetts Medical Society 31-08-2023
Subjects:	Age Airway management Allied Health Personnel Audiometry Birth defects Child Child, Preschool Cleft lip/palate Cleft Palate Cleft Palate - complications Cleft Palate - surgery Clinical Medicine Clinical Medicine General Complications Dental restorative materials Diagnostic Techniques, Surgical Ears & hearing epidemiology Europe Gestational age Growth and Development Hearing loss Humans Infant Infants Kirurgi Language Medicin och hälsovetenskap Oto-rino-laryngologi Otolaryngology Otolaryngology General Otorhinolaryngology Pediatrics Pediatrics General Postoperative Postoperative Complications Postoperative Complications - epidemiology Preschool South America Speech Surgeons Surgery Surgery General Surgical techniques Therapists Velopharyngeal Insufficiency Velopharyngeal Insufficiency - diagnosis Velopharyngeal Insufficiency - etiology South America Europe United Kingdom > UK
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Description
Summary:	In this randomized trial, primary surgery for isolated cleft palate at 6 months of age led to better velopharyngeal function at the age of 5 years than primary surgery at 12 months of age.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Undefined-3 Prof. Gamble and Drs. Persson and Willadsen contributed equally to this article.
ISSN:	0028-4793 1533-4406 1533-4406
DOI:	10.1056/NEJMoa2215162