Search Results - "Plieth, David"

  • Showing 1 - 20 results of 20
Refine Results
  1. 1

    Contribution of Epithelial-derived Fibroblasts to Bleomycin-induced Lung Fibrosis by Tanjore, Harikrishna, Xu, Xiaochuan C, Polosukhin, Vasiliy V, Degryse, Amber L, Li, Bo, Han, Wei, Sherrill, Taylor P, Plieth, David, Neilson, Eric G, Blackwell, Timothy S, Lawson, William E

    “…Lung fibroblasts are key mediators of fibrosis resulting in accumulation of excessive interstitial collagen and extracellular matrix, but their origins are not…”
    Get full text
    Journal Article
  2. 2

    A proximal activator of transcription in epithelial-mesenchymal transition by Venkov, Christo D, Link, Andrew J, Jennings, Jennifer L, Plieth, David, Inoue, Tsutomu, Nagai, Kojiro, Xu, Carol, Dimitrova, Yoana N, Rauscher, Frank J, Neilson, Eric G

    Published in The Journal of clinical investigation (01-02-2007)
    “…Epithelial-mesenchymal transition (EMT) is an important mechanism for phenotypic conversion in normal development and disease states such as tissue fibrosis…”
    Get full text
    Journal Article
  3. 3

    Transcriptional networks in epithelial-mesenchymal transition by Venkov, Christo, Plieth, David, Ni, Terri, Karmaker, Amitava, Bian, Aihua, George, Jr, Alfred L, Neilson, Eric G

    Published in PloS one (30-09-2011)
    “…Epithelial-mesenchymal transition (EMT) changes polarized epithelial cells into migratory phenotypes associated with loss of cell-cell adhesion molecules and…”
    Get full text
    Journal Article
  4. 4

    Characterization of Fibroblast-specific Protein 1 in Pulmonary Fibrosis by Lawson, William E, Polosukhin, Vasiliy V, Zoia, Ornella, Stathopoulos, Georgios T, Han, Wei, Plieth, David, Loyd, James E, Neilson, Eric G, Blackwell, Timothy S

    “…Because fibroblasts produce collagen and other extracellular matrix components that are deposited during tissue fibrosis, defining the behavior of these cells…”
    Get full text
    Journal Article
  5. 5

    Conditional Abatement of Tissue Fibrosis Using Nucleoside Analogs to Selectively Corrupt DNA Replication in Transgenic Fibroblasts by Iwano, Masayuki, Fischer, Andreas, Okada, Hirokazu, Plieth, David, Xue, Chengsen, Danoff, Theodore M., Neilson, Eric G.

    Published in Molecular therapy (01-02-2001)
    “…Progressive tissue fibrosis can compromise epithelial function resulting in organ failure. Appreciating evidence suggests that fibroblasts provide fibrogenic…”
    Get full text
    Journal Article
  6. 6

    Evidence that fibroblasts derive from epithelium during tissue fibrosis by Iwano, Masayuki, Plieth, David, Danoff, Theodore M, Xue, Chengsen, Okada, Hirokazu, Neilson, Eric G

    Published in The Journal of clinical investigation (01-08-2002)
    “…Interstitial fibroblasts are principal effector cells of organ fibrosis in kidneys, lungs, and liver. While some view fibroblasts in adult tissues as nothing…”
    Get full text
    Journal Article
  7. 7

    EGFR Signaling Promotes TGFβ-Dependent Renal Fibrosis by JIANCHUN CHEN, CHEN, Jian-Kang, NAGAI, Kojiro, PLIETH, David, MINGQI TAN, LEE, Tang-Cheng, THREADGILL, David W, NEILSON, Eric G, HARRIS, Raymond C

    “…The mechanisms by which angiotensin II (Ang II) promotes renal fibrosis remain incompletely understood. Ang II both stimulates TGFβ signaling and activates the…”
    Get full text
    Journal Article
  8. 8

    TGF-ß Signaling in Fibroblasts Modulates the Oncogenic Potential of Adjacent Epithelia by Bhowmick, Neil A., Chytil, Anna, Plieth, David, Gorska, Agnieszka E., Dumont, Nancy, Shappell, Scott, Washington, M. Kay, Neilson, Eric G., Moses, Harold L.

    “…Stromal cells can have a significant impact on the carcinogenic process in adjacent epithelia. The role of transforming growth factor–β (TGF-β) signaling in…”
    Get full text
    Journal Article
  9. 9

    TGF-β Signaling in Fibroblasts Modulates the Oncogenic Potential of Adjacent Epithelia by Bhowmick, Neil A., Chytil, Anna, Plieth, David, Gorska, Agnieszka E., Dumont, Nancy, Shappell, Scott, Washington, M. Kay, Neilson, Eric G., Moses, Harold L.

    “…Stromal cells can have a significant impact on the carcinogenic process in adjacent epithelia. The role of transforming growth$factor-\beta$($TGF-\beta$)…”
    Get full text
    Journal Article
  10. 10

    The gatekeeper effect of epithelial-mesenchymal transition regulates the frequency of breast cancer metastasis by CHENGSEN XUE, PLIETH, David, VENKOV, Christo, XU, Carol, NEILSON, Eric G

    Published in Cancer research (Chicago, Ill.) (15-06-2003)
    “…When carcinoma cells metastasize, they change their phenotype to enhance motility. Cells making this switch selectively express S100A4, a p53-associated,…”
    Get full text
    Journal Article
  11. 11

    Antibodies against macrophages that overlap in specificity with fibroblasts by Inoue, Tsutomu, Plieth, David, Venkov, Christo D., Xu, Carol, Neilson, Eric G.

    Published in Kidney international (01-06-2005)
    “…Antibodies against macrophages that overlap in specificity with fibroblasts. Fibroblasts can be misidentified as macrophages because both cell types share…”
    Get full text
    Journal Article
  12. 12

    Phosphatidylinositol 3-kinase signaling determines kidney size by Chen, Jian-Kang, Nagai, Kojiro, Chen, Jianchun, Plieth, David, Hino, Masayo, Xu, Jinxian, Sha, Feng, Ikizler, T Alp, Quarles, C Chad, Threadgill, David W, Neilson, Eric G, Harris, Raymond C

    Published in The Journal of clinical investigation (01-06-2015)
    “…Kidney size adaptively increases as mammals grow and in response to the loss of 1 kidney. It is not clear how kidneys size themselves or if the processes that…”
    Get full text
    Journal Article
  13. 13

    Detection of human papillomavirus in squamous neoplasm of the penis by Sarkar, F H, Miles, B J, Plieth, D H, Crissman, J D

    Published in The Journal of urology (01-02-1992)
    “…Infection of the external human urogenital system with human papillomavirus has been implicated with the development of genital cancer. A modified polymerase…”
    Get more information
    Journal Article
  14. 14
  15. 15
  16. 16
  17. 17

    TECHNICAL NOTE: Antibodies against macrophages that overlap in specificity with fibroblasts by Inoue, Tsutomu, Plieth, David, Venkov, Christo D, Xu, Carol, Neilson, Eric G

    Published in Kidney international (01-06-2005)
    “…Background. Fibroblasts can be misidentified as macrophages because both cell types share antigens that are associated with popular antibodies targeting the…”
    Get full text
    Journal Article
  18. 18

    Evidence that fibroblasts derive from epithelium during tissue fibrosis by Iwano, Masayuki, Plieth, David, Danoff, Theodore M., Xue, Chengsen, Okada, Hirokazu, Neilson, Eric G.

    Published in The Journal of clinical investigation (01-08-2002)
    “…Interstitial fibroblasts are principal effector cells of organ fibrosis in kidneys, lungs, and liver. While some view fibroblasts in adult tissues as nothing…”
    Get full text
    Journal Article
  19. 19

    TGF-[beta] signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia by Bhowmick, Neil A, Chytil, Anna, Plieth, David, Gorska, Agnieszka E

    “…Stromal cells can have a significant impact on the carcinogenic process in adjacent epithelia. The role of transforming growth factor-[beta] (TGF-[beta])…”
    Get full text
    Journal Article
  20. 20