Search Results - "Plevova, K"

Detailed analysis of therapy-driven clonal evolution of TP53 mutations in chronic lymphocytic leukemia by Malcikova, J, Stano-Kozubik, K, Tichy, B, Kantorova, B, Pavlova, S, Tom, N, Radova, L, Smardova, J, Pardy, F, Doubek, M, Brychtova, Y, Mraz, M, Plevova, K, Diviskova, E, Oltova, A, Mayer, J, Pospisilova, S, Trbusek, M

“…In chronic lymphocytic leukemia (CLL), the worst prognosis is associated with TP53 defects with the affected patients being potentially directed to alternative…”
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High-quality full-length immunoglobulin profiling with unique molecular barcoding by Turchaninova, M A, Davydov, A, Britanova, O V, Shugay, M, Bikos, V, Egorov, E S, Kirgizova, V I, Merzlyak, E M, Staroverov, D B, Bolotin, D A, Mamedov, I Z, Izraelson, M, Logacheva, M D, Kladova, O, Plevova, K, Pospisilova, S, Chudakov, D M

“…This protocol enables high-throughput sequencing analysis of the full-length immunoglobulin repertoires in human and mouse using unique molecular identifiers…”
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Low-burden TP53 mutations in chronic phase of myeloproliferative neoplasms: association with age, hydroxyurea administration, disease type and JAK2 mutational status by Kubesova, B, Pavlova, S, Malcikova, J, Kabathova, J, Radova, L, Tom, N, Tichy, B, Plevova, K, Kantorova, B, Fiedorova, K, Slavikova, M, Bystry, V, Kissova, J, Gisslinger, B, Gisslinger, H, Penka, M, Mayer, J, Kralovics, R, Pospisilova, S, Doubek, M

“…The multistep process of TP53 mutation expansion during myeloproliferative neoplasm (MPN) transformation into acute myeloid leukemia (AML) has been documented…”
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Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2 by Strefford, J C, Sutton, L-A, Baliakas, P, Agathangelidis, A, Malčíková, J, Plevova, K, Scarfó, L, Davis, Z, Stalika, E, Cortese, D, Cahill, N, Pedersen, L B, di Celle, P F, Tzenou, T, Geisler, C, Panagiotidis, P, Langerak, A W, Chiorazzi, N, Pospisilova, S, Oscier, D, Davi, F, Belessi, C, Mansouri, L, Ghia, P, Stamatopoulos, K, Rosenquist, R

“…Recent studies have revealed recurrent mutations of the NOTCH1 , SF3B1 and BIRC3 genes in chronic lymphocytic leukemia (CLL), especially among aggressive,…”
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Multiple productive IGH rearrangements denote oligoclonality even in immunophenotypically monoclonal CLL by Brazdilova, K, Plevova, K, Skuhrova Francova, H, Kockova, H, Borsky, M, Bikos, V, Malcikova, J, Oltova, A, Kotaskova, J, Tichy, B, Brychtova, Y, Mayer, J, Doubek, M, Pospisilova, S

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Additional trisomies amongst patients with chronic lymphocytic leukemia carrying trisomy 12: the accompanying chromosome makes a difference by Baliakas, Panagiotis, Puiggros, Anna, Xochelli, Aliki, Sutton, Lesley-Ann, Nguyen-Khac, Florence, Gardiner, Anne, Plevova, Karla, Minga, Eva, Hadzidimitriou, Anastasia, Walewska, Renata, McCarthy, Helen, Ortega, Margarita, Collado, Rosa, González, Teresa, Granada, Isabel, Luño, Elisa, Kotašková, Jana, Moysiadis, Theodoros, Davis, Zadie, Stavroyianni, Niki, Anagnostopoulos, Achilles, Strefford, Jonathan C, Pospisilova, Sarka, Davi, Frederic, Athanasiadou, Anastasia, Rosenquist, Richard, Oscier, David, Espinet, Blanca, Stamatopoulos, Kostas

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FOXO1‐RICTOR AXIS INDUCES AKT PHOSPHORYLATION DURING CLL CELL ADAPTATION TO BCR INHIBITORS: IMPLICATIONS FOR COMBINATORIAL THERAPY by Ondrisova, L., Seda, V., Hoferkova, E., Chiodin, G., Hlavac, K., Kostalova, L., Pavlasova, G. Mladonicka, Filip, D., Zeni, P. Faria, Oppelt, J., Panovska, A., Plevova, K., Pospisilova, S., Simkovic, M., Vrbacky, F., Lysak, D., Fernandes, S. M., Davids, M. S., Maiques‐Diaz, A., Charalampopoulou, S., Martin‐Subero, J. I., Brown, J. R., Doubek, M., Forconi, F., Mayer, J., Mraz, M.

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P620: DYNAMICS OF GENOMIC ABERRATIONS IN RELATION TO DISEASE ACTIVITY IN UNTREATED PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA by Navrkalova, V., Kotaskova, J., Plevova, K., Reigl, T., Valisova, M., Bohunova, M., Zenatova, M., Radova, L., Panovska, A., Pospisilova, S.

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ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres by Navrkalova, Veronika, Young, Emma, Baliakas, Panagiotis, Radova, Lenka, Sutton, Lesley-Ann, Plevova, Karla, Mansouri, Larry, Ljungström, Viktor, Ntoufa, Stavroula, Davis, Zadie, Juliusson, Gunnar, Smedby, Karin E, Belessi, Chrysoula, Panagiotidis, Panagiotis, Touloumenidou, Tasoula, Davi, Frederic, Langerak, Anton W, Ghia, Paolo, Strefford, Jonathan C, Oscier, David, Mayer, Jiri, Stamatopoulos, Kostas, Pospisilova, Sarka, Rosenquist, Richard, Trbusek, Martin

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P608: DISTINCT P53 PHOSPHORYLATION PATTERNS IN CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS ARE REFLECTED IN CIRCUMJACENT PATHWAYS’ ACTIVATION UPON DNA DAMAGE by Pesova, M., Mancikova, V., Helma, R., Pavlova, S., Hejret, V., Taus, P., Hynst, J., Plevova, K., Kotaskova, J., Malcikova, J., Pospisilova, S.

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P614: SUBCLONAL ARCHITECTURE OF CHROMOSOMES REVEALED BY SINGLE‐CELL ANALYSIS OF GENE EXPRESSION IN A PATIENT WITH CLONAL EVOLUTION OF RELAPSING/REFRACTORY CLL by Kotaskova, J., Kurucova, T., Reblova, K., Valisova, M., Zavacka, K., Mareckova, A., Bohunova, M., Pavlova, S., Malcikova, J., Navrkalova, V., Jarosova, M., Doubek, M., Plevova, K., Pospisilova, S.

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DNA METHYLATION PROFILING IN CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS CARRYING STEREOTYPED B-CELL RECEPTORS: A DIFFERENT CELLULAR ORIGIN FOR SUBSET #2? by Bhoi, Sujata, Mansouri, Larry, Castellano, G., Sutton, Lesley Ann, Papakonstantinou, N., Queiros, A., Ek, S., Emruli, V. K., Plevova, K., Ntoufa, S., Davis, Z., Young, Emma, Göransson, Hanna, Isaksson, Anders, Smedby, K. E., Gaidano, G., Langerak, A. W., Davi, F., Rossi, D., Oscier, D., Pospisilova, S., Ghia, P., Campo, E., Stamatopoulos, K., Martin-Subero, J. -I, Rosenquist, Richard

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P1282: DISEASE‐SPECIFIC U1 SPLICEOSOMAL RNA MUTATIONS IN MATURE B‐CELL NEOPLASMS by Nadeu, F., Shuai, S., Clot, G., Hilton, L. K., Diaz‐Navarro, A., Martín, S., Royo, R., Baumann, T., Kulis, M., López‐Oreja, I., Cossio, M., Lu, J., Ljungström, V., Young, E., Plevova, K., Knisbacher, B. A., Lin, Z., Hahn, C. K., Bousquets, P., Alcoceba, M., González, M., Colado, E., Aymerich, M., Terol, M. J., Rivas‐Delgado, A., Enjuanes, A., Ruiz‐Gaspà, S., Chatzikonstantinou, T., Hägerstrand, D., Jylhä, C., Skaftason, A., Mansouri, L., Stranska, K., Doubek, M., Gastel‐Mol, E. J., Davis, Z., Walewska, R., Scarfò, L., Trentin, L., Visentin, A., Parikh, S. A., Rabe, K. G., Moia, R., Armand, M., Rossi, D., Davi, F., Gaidano, G., Kay, N. E., Shanafelt, T., Ghia, P., Oscier, D., Langerak, A. W., Beà, S., López‐Guillermo, A., Neuberg, D., Wu, C. J., Getz, G., Pospisilova, S., Stamatopoulos, K., Rosenquist, R., Huber, W., Zenz, T., Colomer, D., Martín‐Subero, J. I., Delgado, J., Morin, R. D., Stein, L. D., Puente, X. S., Campo, E.

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No Improvement In Long-Term Overall Survival After The Introduction Of Chemo(Immuno)Therapy For Chronic Lymphocytic Leukemia Patients Belonging To Stereotyped Subset #2 by Baliakas, Panagiotis, Mattsson, Mattias, Hadzidimitriou, A., Minga, E., Agathangelidis, A., Sutton, L. A., Scarfo, L., Davis, Z., Yan, X. J., Plevova, K., Sandberg, Y., Vojdeman, F. Juhl, Tzenou, T., Chu, C. C., Veroneze, S., Mansouri, Larry, Smedby, K. E., Giudicelli, V., Nguyen-Khac, F., Panagiotidis, P., Juliusson, G., Anagnostopoulos, A., Lefranc, M. P., Trentin, L., Catherwood, M., Montillo, M., Niemann, C. U., Langerak, A. W., Pospisilova, S., Stavroyianni, N., Chiorazzi, N., Oscier, D., Jelinek, D. F., Shanafelt, T., Darzentas, N., Belessi, C., Davi, F., Ghia, P., Rosenquist, Richard, Stamatopoulos, Kostas

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REFINING PROGNOSIS OF CHRONIC LYMPHOCYTIC LEUKEMIA WITH SOMATICALLY HYPERMUTATED B-CELL RECEPTORS: A NOVEL PROGNOSTIC INDEX ON BEHALF OF THE EUROPEAN RESEARCH INITIATIVE ON CLL (ERIC) by Baliakas, Panagiotis, Hadzidimitriou, A., Mattsson, Mattias, Xochelli, Aliki, Sutton, L. A., Minga, E., Scarfo, L., Rossi, D., Davis, Z., Agathangelidis, A., Villamor, N., Parker, H., Kotaskova, J., Stalika, E., Plevova, K., Mansouri, Larry, Cortese, Diego, Navarro Lopez, A., Delgado, J., Larrayoz, M., Anagnostopoulos, A., Belessi, C., Smedby, K. E., Juliusson, G., Strefford, J. C., Pospisilova, S., Oscier, D., Gaidano, G., Campo, E., Ghia, P., Rosenquist, Richard, Stamatopoulos, Kostas

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1.8 MicroRNA Mutational Analysis in Patients with Chronic Lymphocytic Leukemia by Lochmanova, J, Navrkalova, V, Dvorakova, B, Mraz, M, Pavlova, S, Plevova, K, Tichy, B, Malcikova, J, Sebejova, L, Benes, V, Rausch, T, Brychtova, Y, Doubek, M, Trbusek, M, Mayer, J, Pospisilova, S

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666 Analysis of microRNAs associated with aggressive subtype of chronic lymphocytic leukaemia harbouring inactivated p53 by Pavlova, S, Mraz, M, Plevova, K, Tvaruzkova, Z, Malcikova, J, Trbusek, M, Brychtova, Y, Doubek, M, Mayer, J, Pospisilova, S

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Post-translational modifications regulate signalling by Ror1 by Kaucká, M., Krejčí, P., Plevová, K., Pavlová, Š., Procházková, J., Janovská, P., Valnohová, J., Kozubík, A., Pospíšilová, Š., Bryja, V.

“…Aim:  In this study, we analysed the post‐translational modification of receptor tyrosine kinase‐like orphan receptor (Ror1). Ror1 is highly upregulated in B…”
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Isomerizational and conformational study of 3-fluorophenylamino-2-acetyl propenenitrile (FPAAPN) by Gatial, A., Dorotíková, S., Plevová, K., Milata, V., Prónayová, N., Matějka, P.

“…[Display omitted] •Spectral properties of (FH4C6)NHCHC(CN)(COCH3) have been studied.•ZZa and EZa conformers of the molecule were determined as the most…”
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Cytogenetic complexity in chronic lymphocytic leukemia: definitions, associations, and clinical impact by Baliakas, Panagiotis, Jeromin, Sabine, Iskas, Michalis, Puiggros, Anna, Plevova, Karla, Nguyen-Khac, Florence, Davis, Zadie, Rigolin, Gian Matteo, Visentin, Andrea, Xochelli, Aliki, Delgado, Julio, Baran-Marszak, Fanny, Stalika, Evangelia, Abrisqueta, Pau, Durechova, Kristina, Papaioannou, George, Eclache, Virginie, Dimou, Maria, Iliakis, Theodoros, Collado, Rosa, Doubek, Michael, Calasanz, M. Jose, Ruiz-Xiville, Neus, Moreno, Carolina, Jarosova, Marie, Leeksma, Alexander C., Panayiotidis, Panayiotis, Podgornik, Helena, Cymbalista, Florence, Anagnostopoulos, Achilles, Trentin, Livio, Stavroyianni, Niki, Davi, Fred, Ghia, Paolo, Kater, Arnon P., Cuneo, Antonio, Pospisilova, Sarka, Espinet, Blanca, Athanasiadou, Anastasia, Oscier, David, Haferlach, Claudia, Stamatopoulos, Kostas

“…Recent evidence suggests that complex karyotype (CK) defined by the presence of ≥3 chromosomal aberrations (structural and/or numerical) identified by using…”
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