Search Results - "Pletzenauer, Robert"

Biophysical Characterization of Adeno-Associated Virus Vectors Using Ion-Exchange Chromatography Coupled to Light Scattering Detectors by Wagner, Christina, Innthaler, Bernd, Lemmerer, Martin, Pletzenauer, Robert, Birner-Gruenberger, Ruth

“…Ion-exchange chromatography coupled to light scattering detectors represents a fast and simple analytical method for the assessment of multiple critical…”
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Adeno-Associated Virus-like Particles' Response to pH Changes as Revealed by nES-DMA by Zoratto, Samuele, Heuser, Thomas, Friedbacher, Gernot, Pletzenauer, Robert, Graninger, Michael, Marchetti-Deschmann, Martina, Weiss, Victor U

“…Gas-phase electrophoresis on a nano-Electrospray Gas-phase Electrophoretic Mobility Molecular Analyzer (nES GEMMA) separates single-charged, native analytes…”
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Knockout of an endogenous mannosyltransferase increases the homogeneity of glycoproteins produced in Pichia pastoris by Krainer, Florian W., Gmeiner, Christoph, Neutsch, Lukas, Windwarder, Markus, Pletzenauer, Robert, Herwig, Christoph, Altmann, Friedrich, Glieder, Anton, Spadiut, Oliver

“…The yeast Pichia pastoris is a common host for the recombinant production of biopharmaceuticals, capable of performing posttranslational modifications like…”
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Adeno-associated Virus Virus-like Particle Characterization via Orthogonal Methods: Nanoelectrospray Differential Mobility Analysis, Asymmetric Flow Field-Flow Fractionation, and Atomic Force Microscopy by Zoratto, Samuele, Weiss, Victor U, Friedbacher, Gernot, Buengener, Carsten, Pletzenauer, Robert, Foettinger-Vacha, Alexandra, Graninger, Michael, Allmaier, Guenter

“…Adeno-associated virus (AAV)-based virus-like particles (VLPs) are thriving vectors of choice in the biopharmaceutical field of gene therapy. Here, a method to…”
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Orthogonal characterization of rAAV9 reveals unexpected transgene heterogeneity by Eisenhut, Peter, Andorfer, Peter, Haid, Andrea, Jokl, Beatrice, Manhartsberger, Raffaela, Fuchsberger, Felix, Innthaler, Bernd, Lengler, Johannes, Kraus, Barbara, Pletzenauer, Robert, Hernandez Bort, Juan A., Unterthurner, Sabine

“…Recombinant adeno-associated virus (rAAV) is the most widely used viral vector for in vivo human gene therapy. To ensure safety and efficacy of gene therapy…”
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Molecular weight determination of adeno‐associate virus serotype 8 virus‐like particle either carrying or lacking genome via native nES gas‐phase electrophoretic molecular mobility analysis and nESI QRTOF mass spectrometry by Zoratto, Samuele, Weiss, Victor U., Horst, Jerre, Commandeur, Jan, Buengener, Carsten, Foettinger‐Vacha, Alexandra, Pletzenauer, Robert, Graninger, Michael, Allmaier, Guenter

“…Virus‐like particles (VLPs) are proteinaceous shells derived from viruses lacking any viral genomic material. Adeno‐associated virus (AAV) is a non‐enveloped…”
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Purification and basic biochemical characterization of 19 recombinant plant peroxidase isoenzymes produced in Pichia pastoris by Krainer, Florian W., Pletzenauer, Robert, Rossetti, Laura, Herwig, Christoph, Glieder, Anton, Spadiut, Oliver

“…•A novel 2-step purification for recombinant HRP from P. pastrois was developed.•Both purification steps are negative chromatography steps.•The amount of…”
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Glyco-variant library of the versatile enzyme horseradish peroxidase by Capone, Simona, Pletzenauer, Robert, Maresch, Daniel, Metzger, Karl, Altmann, Friedrich, Herwig, Christoph, Spadiut, Oliver

“…When the glycosylated plant enzyme horseradish peroxidase (HRP) is conjugated to specific antibodies, it presents a powerful tool for medical applications. The…”
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Proton-transfer-reaction mass spectrometry (PTR-MS) for online monitoring of glucose depletion and cell concentrations in HEK 293 gene therapy processes by Bayer, Benjamin, Maccani, Andreas, Jahn, Johanna, Duerkop, Mark, Kapeller, Ewald, Pletzenauer, Robert, Kraus, Barbara, Striedner, Gerald, Hernandez Bort, Juan A.

“…Objectives The applicability of proton-transfer-reaction mass spectrometry (PTR-MS) as a versatile online monitoring tool to increase consistency and…”
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An adsorbent monolith device to augment the removal of uraemic toxins during haemodialysis by Sandeman, Susan R., Howell, Carol A., Phillips, Gary J., Zheng, Yishan, Standen, Guy, Pletzenauer, Robert, Davenport, Andrew, Basnayake, Kolitha, Boyd, Owen, Holt, Stephen, Mikhalovsky, Sergey V.

“…Adsorbents designed with porosity which allows the removal of protein bound and high molecular weight uraemic toxins may improve the effectiveness of…”
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