Search Results - "Pleouras, Dimitrios"
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Simulation of atherosclerotic plaque growth using computational biomechanics and patient-specific data
Published in Scientific reports (15-10-2020)“…Atherosclerosis is the one of the major causes of mortality worldwide, urging the need for prevention strategies. In this work, a novel computational model is…”
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Journal Article -
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A Strategy for the In-Silico Assessment of Drug Eluting Stents: A Comparative Study for the Evaluation of Retinoic Acid as a Novel Drug Candidate for Drug Eluting Stents
Published in IEEE open journal of engineering in medicine and biology (01-01-2025)“…In this work, a methodology for the in-silico evaluation of drug eluting stents (DES) is presented. A stent model developed by Rontis S.A. has been employed…”
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Journal Article -
3
Combining Computational Fluid Dynamics, Structural Analysis, and Machine Learning to Predict Cerebrovascular Events: A Mild ML Approach
Published in Diagnostics (Basel) (02-10-2024)“…: Cerebrovascular events, such as strokes, are often preceded by the rupture of atherosclerotic plaques in the carotid arteries. This work introduces a novel…”
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Journal Article -
4
A Novel Approach to Generate a Virtual Population of Human Coronary Arteries for In Silico Clinical Trials of Stent Design
Published in IEEE open journal of engineering in medicine and biology (01-01-2021)“…Goal: To develop a cardiovascular virtual population using statistical modeling and computational biomechanics. Methods: A clinical data augmentation algorithm…”
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Journal Article -
5
Error Propagation in the Simulation of Atherosclerotic Plaque Growth and the Prediction of Atherosclerotic Disease Progression
Published in Diagnostics (Basel) (08-12-2021)“…Assessments of coronary artery disease can be achieved using non-invasive computed tomography coronary angiography (CTCA). CTCA can be further used for the 3D…”
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Journal Article -
6
Accurate adventitia reconstruction; significant or not in atherosclerotic plaque growth simulationsƒ A comparative study
Published in 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) (01-07-2023)“…A reform in the diagnosis and treatment process is urgently required as carotid artery disease remains a leading cause of death in the world. To this purpose,…”
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Conference Proceeding Journal Article -
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A Machine Learning Model for the prediction of the progression of carotid arterial stenoses
Published in 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) (01-01-2023)“…Atherosclerotic carotid plaque development results in a steady narrowing of the artery lumen, which may eventually trigger catastrophic plaque rupture leading…”
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Conference Proceeding Journal Article -
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Enhancing risk prediction capabilities in patients with carotid artery disease using a 2-level computational approach
Published in 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) (01-01-2023)“…One of the main causes of death worldwide is carotid artery disease, which causes increasing arterial stenosis and may induce a stroke. To address this…”
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Conference Proceeding Journal Article -
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Computational modeling of atherosclerotic plaque progression through an efficient 3D agent-based modeling approach
Published in 2022 IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) (27-09-2022)“…Since atherosclerosis has been declared as the leading cause of mortality worldwide, the imminent need for the design and development of straightforward…”
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Conference Proceeding -
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Computational modeling of atherosclerotic plaque progression in carotid lesions with moderate degree of stenosis
Published in 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) (01-11-2021)“…Carotid atherosclerotic plaque growth leads to the progressive luminal stenosis of the vessel, which may erode or rupture causing thromboembolism and cerebral…”
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Conference Proceeding Journal Article -
11
Investigation of the drug release time from the biodegrading coating of an everolimus eluting stent
Published in 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) (01-11-2021)“…This case-study examines the release time of the everolimus drug from an experimental biodegrading coating of a Rontis corp. drug eluting stent (DES). The…”
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Conference Proceeding Journal Article -
12
Prediction of the development of coronary atherosclerotic plaques using computational modeling in 3D reconstructed coronary arteries
Published in 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) (01-07-2020)“…In this work we present a novel method for the prediction and generation of atherosclerotic plaques. This is performed in a two-step approach, by employing…”
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Conference Proceeding -
13
Prediction of the atherosclerotic plaque development in carotid arteries; the effect of T-cells
Published in 2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) (2022)“…The carotid artery disease is one of the leading causes of mortality worldwide, as it leads to the progressive arterial stenosis that may result to stroke. To…”
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Conference Proceeding -
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A computational multi-level atherosclerotic plaque growth model for coronary arteries
Published in 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (01-07-2019)“…In this work, we present a novel computational approach for the prediction of atherosclerotic plaque growth. In particular, patient-specific coronary computed…”
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Conference Proceeding Journal Article -
15
Investigation of Drug Eluting Stents performance in human atherosclerotic artery through in silico modeling
Published in 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) (01-11-2021)“…Atherosclerosis is a chronic inflammatory disease associated with heart attack and stroke. It causes the growth of atherosclerotic plaques inside the arterial…”
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Conference Proceeding Journal Article -
16
Investigation of crimping effects on the stent deployment through in silico modeling
Published in 2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) (2022)“…Atherosclerosis is one of the most mortal diseases that affects the arterial vessels, due to accumulation of plaque, altering the hemodynamic environment of…”
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Conference Proceeding