Search Results - "Plenz, Gabriele"

KRP-203, Sphingosine 1-Phosphate Receptor Type 1 Agonist, Ameliorates Atherosclerosis in LDL-R−/− Mice by Potì, Francesco, Gualtieri, Fabio, Sacchi, Sandro, Weien-Plenz, Gabriele, Varga, Georg, Brodde, Martin, Weber, Christian, Simoni, Manuela, Nofer, Jerzy-Roch

“…OBJECTIVE—Sphingosine 1-phosphate (S1P) partly accounts for antiatherogenic properties of high-density lipoproteins. We previously demonstrated that FTY720, a…”
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Npp1 promotes atherosclerosis in ApoE knockout mice by Nitschke, Yvonne, Weissen‐Plenz, Gabriele, Terkeltaub, Robert, Rutsch, Frank

“…Ecto‐nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) generates inorganic pyrophosphate (PPi), a physiologic inhibitor of hydroxyapatite deposition. In a…”
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Vascular collagens: spotlight on the role of type VIII collagen in atherogenesis by Plenz, Gabriele A.M, Deng, Mario C, Robenek, Horst, Völker, Wolfgang

“…Collagens play a central role in maintaining the integrity and stability of the undiseased as well as of the atherosclerotic vessel wall. An imbalanced…”
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Expanding Expression of the 5-Lipoxygenase Pathway within the Arterial Wall during Human Atherogenesis by Spanbroek, Rainer, Gräbner, Rolf, Lötzer, Katharina, Hildner, Markus, Urbach, Anja, Rühling, Katharina, Michael P. W. Moos, Kaiser, Brigitte, Cohnert, Tina U., Wahlers, Thorsten, Zieske, Arthur, Plenz, Gabriele, Robenek, Horst, Salbach, Peter, Kühn, Hartmut, Rådmark, Olof, Samuelsson, Bengt, Andreas J. R. Habenicht

“…Oxidation products of low-density lipoproteins have been suggested to promote inflammation during atherogenesis, and reticulocyte-type 15-lipoxygenase has been…”
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Damage of Guinea Pig Heart and Arteries by a Trioleate-Enriched Diet and of Cultured Cardiomyocytes by Oleic Acid by Krieglstein, Josef, Kewitz, Tobias, Kirchhefer, Uwe, Hofnagel, Oliver, Weissen-Plenz, Gabriele, Reinbold, Michael, Klumpp, Susanne

“…Background: Mono-unsaturated fatty acids (MUFAs) like oleic acid have been shown to cause apoptosis of cultured endothelial cells by activating protein…”
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Autophagy facilitates secretion and protects against degeneration of the Harderian gland by Koenig, Ulrich, Fobker, Manfred, Lengauer, Barbara, Brandstetter, Marlene, Resch, Guenter P, Gröger, Marion, Plenz, Gabriele, Pammer, Johannes, Barresi, Caterina, Hartmann, Christine, Rossiter, Heidemarie

“…The epithelial derived Harderian gland consists of 2 types of secretory cells. The more numerous type A cells are responsible for the secretion of lipid…”
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Expression of NPP1 is regulated during atheromatous plaque calcification by Nitschke, Yvonne, Hartmann, Simone, Torsello, Giovanni, Horstmann, Rüdiger, Seifarth, Harald, Weissen‐Plenz, Gabriele, Rutsch, Frank

“…Mutations of the ENPP1 gene encoding ecto‐nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) are associated with medial calcification in infancy. While the…”
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Connexin Expression Patterns in Arrhythmogenic Right Ventricular Cardiomyopathy by Paul, Matthias, MD, Wichter, Thomas, MD, Gerss, Joachim, PhD, Arps, Volker, PhD, Schulze-Bahr, Eric, MD, Robenek, Horst, PhD, Breithardt, Günter, MD, Weissen-Plenz, Gabriele, PhD

“…Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inheritable myocardial disease accounting for ventricular tachycardia and sudden death in the…”
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Proinflammatory Cytokines Regulate LOX-1 Expression in Vascular Smooth Muscle Cells by Hofnagel, Oliver, Luechtenborg, Birgit, Stolle, Katrin, Lorkowski, Stefan, Eschert, Heike, Plenz, Gabriele, Robenek, Horst

“…OBJECTIVE—Atherogenesis represents a type of chronic inflammation and involves elements of the immune response, eg, the expression of proinflammatory…”
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Freeze‐fracture replica immunolabelling reveals caveolin‐1 in the human cardiomyocyte plasma membrane by Robenek, Horst, Weissen‐Plenz, Gabriele, Severs, Nicholas J.

“…Mutations in or ablation of the gene encoding caveolin‐3, a protein of muscle cell caveolae, result in forms of muscular dystrophy and cardiomyopathy. Another…”
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Differential modulation of caveolin-1 expression in cells of the vasculature by statins by Plenz, Gabriele A M, Hofnagel, Oliver, Robenek, Horst

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Expression of the Novel Scavenger Receptor SR-PSOX in Cultured Aortic Smooth Muscle Cells and Umbilical Endothelial Cells by Hofnagel, Oliver, Luechtenborg, Birgit, Plenz, Gabriele, Robenek, Horst

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Transgenic model of cardiac rhabdomyosarcoma formation by Köbbert, Christiane, PhD, Möllmann, Christa, Schäfers, Michael, MD, Hermann, Sven, MD, Baba, Hideo A., MD, Hoffmeier, Andreas, MD, Breithardt, Günter, MD, Scheld, Hans H., MD, Weissen–Plenz, Gabriele, PhD, Sindermann, Jürgen R., MD

“…Objectives Cardiac rhabdomyosarcomas are rare, and the pathogenesis of this detrimental disease is widely unknown. Most data are obtained from case reports or…”
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Activation of the cardiac interleukin-6 system in advanced heart failure by Gabriele, Plenz, Zhi Fang, Song, Tonny D.T., Tjan, Carsten, Koenig, Hideo A., Baba, Michael, Erren, Markus, Flesch, Thomas, Wichter, Hans H., Scheld, Mario C., Deng

“…Objectives: The study objective was to assess the cardiac expression of interleukin-6 (IL6) and its receptor (IL6R) in advanced heart failure. Background:…”
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Aortic dissection associated with Cogans's syndrome: deleterious loss of vascular structural integrity is associated with GM-CSF overstimulation in macrophages and smooth muscle cells by Weissen-Plenz, Gabriele, Sezer, Omer, Vahlhaus, Christian, Robenek, Horst, Hoffmeier, Andreas, Tjan, Tonny D T, Scheld, Hans H, Sindermann, Jürgen R

“…Cogan's syndrome is a rare disorder of unknown origin characterized by inflammatory ocular disease and vestibuloauditory symptoms. Systemic vasculitis is found…”
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Smooth Muscle Cells Express Granulocyte-Macrophage Colony-Stimulating Factor in the Undiseased and Atherosclerotic Human Coronary Artery by Plenz, Gabriele, Koenig, Carsten, Severs, Nicholas J, Robenek, Horst

“…Granulocyte-macrophage colony-stimulating factor (GM-CSF), one of a family of cytokines that regulate proliferation in macrophages and other types of cells,…”
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Paracrine or virus-mediated induction of decorin expression by endothelial cells contributes to tube formation and prevention of apoptosis in collagen lattices by Schönherr, Elke, O'Connell, Brian C., Schittny, Johannes, Robenek, Horst, Fastermann, Dirk, Fisher, Larry W., Plenz, Gabriele, Vischer, Peter, Young, Marian F., Kresse, Hans

“…Resting endothelial cells express the small proteoglycan biglycan, whereas sprouting endothelial cells also synthesize decorin, a related proteoglycan. Here we…”
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What are appropriate controls for cardiac interleukin-6 expression in heart failure? by Plenz, Gabriele A M, Eschert, Heike, Deng, Mario C

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Hypophosphatemia, Hyperphosphaturia, and Bisphosphonate Treatment Are Associated With Survival Beyond Infancy in Generalized Arterial Calcification of Infancy by Rutsch, Frank, Boyer, Petra, Nitschke, Yvonne, Ruf, Nico, Lorenz-Depierieux, Bettina, Wittkampf, Tanja, Weissen-Plenz, Gabriele, Fischer, Rudolf-Josef, Mughal, Zulf, Gregory, John W, Davies, Justin H, Loirat, Chantal, Strom, Tim M, Schnabel, Dirk, Nurnberg, Peter, Terkeltaub, Robert, GACI Study Group

“…Hypophosphatemia, Hyperphosphaturia, and Bisphosphonate Treatment Are Associated With Survival Beyond Infancy in Generalized Arterial Calcification of Infancy…”
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Statins and foam cell formation: Impact on LDL oxidation and uptake of oxidized lipoproteins via scavenger receptors by Hofnagel, Oliver, Luechtenborg, Birgit, Weissen-Plenz, Gabriele, Robenek, Horst

“…The uptake of oxidized lipoproteins via scavenger receptors and the ensuing formation of foam cells are key events during atherogenesis. Foam cell formation…”
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