Search Results - "Plaza, Carmen"
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Bronchial asthma triggered by house dust mites in patients with local allergic rhinitis
Published in Allergy (Copenhagen) (01-08-2019)“…Background Over 30% of local allergic rhinitis (LAR) patients self‐report bronchial symptoms suggestive of asthma, but the relationship between the allergen…”
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Contribution of ADAMTS1 as a tumor suppressor gene in human breast carcinoma. Linking its tumor inhibitory properties to its proteolytic activity on nidogen‐1 and nidogen‐2
Published in International journal of cancer (15-11-2013)“…The extracellular protease ADAMTS1 (A disintegrin and metalloprotease with thrombospondin repeats 1) has been described as an anti‐angiogenic molecule and its…”
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3
Eicosanoid mediator profiles in different phenotypes of nonsteroidal anti‐inflammatory drug‐induced urticaria
Published in Allergy (Copenhagen) (01-06-2019)“…Background The role of arachidonic acid metabolites in NSAID‐induced hypersensitivity has been studied in depth for NSAID‐exacerbated respiratory disease…”
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4
Hypersensitivity reactions to nonsteroidal anti-inflammatory drugs: an update on pharmacogenetics studies
Published in Pharmacogenomics (01-08-2018)“…Nonsteroidal anti-inflammatory drugs are the medications most frequently involved in hypersensitivity reactions to drugs. These can be induced by specific…”
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Gallic Acid: A Natural Phenolic Compound Exerting Antitumoral Activities in Colorectal Cancer via Interaction with G-Quadruplexes
Published in Cancers (26-05-2022)“…Natural phenolic compounds have gained momentum for the prevention and treatment of cancer, but their antitumoral mechanism of action is not yet well…”
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6
Novel locus for atopic dermatitis in African Americans and replication in European Americans
Published in Journal of allergy and clinical immunology (01-03-2019)“…To date, 31 genetic loci have been identified through genome-wide association studies (GWASs), mapping to genes involved in immune regulation and skin barrier…”
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ADAMTS1 protease is required for a balanced immune cell repertoire and tumour inflammatory response
Published in Scientific reports (30-08-2018)“…Recent advances have emphasized the relevance of studying the extracellular microenvironment given its main contribution to tissue homeostasis and disease…”
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Effect of an algorithm for automatic placing of standardised test order sets on low-value appointments and attendance rates at four Spanish teaching hospitals: an interrupted time series analysis
Published in BMJ open (24-01-2024)“…ObjectiveReducing backlogs for elective care is a priority for healthcare systems. We conducted an interrupted time series analysis demonstrating the effect of…”
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Transcriptional Profiling of Dendritic Cells in a Mouse Model of Food‐Antigen‐Induced Anaphylaxis Reveals the Upregulation of Multiple Immune‐Related Pathways
Published in Molecular nutrition & food research (01-02-2019)“…Scope Much of the knowledge about gene expression during anaphylaxis comes from candidate gene studies. Despite their potential role, expression changes in…”
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10
Direct intranasal application of the solid phase of ImmunoCAP® increases nasal specific immunoglobulin E detection in local allergic rhinitis patients
Published in International forum of allergy & rhinology (01-01-2018)“…Background The measurement of nasal specific IgE (NsIgE) in local allergic rhinitis (LAR) patients is challenging and shows variability. The objective of this…”
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A Nonsynonymous FCER1B SNP is Associated with Risk of Developing Allergic Rhinitis and with IgE Levels
Published in Scientific reports (21-01-2016)“…Allergic rhinitis is associated with elevated serum IgE levels. IgE response is mediated by the high-affinity IgE receptor (FcεRI), which is polymorphic…”
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12
A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification
Published in Cell research (01-06-2012)“…The MLL-AF4 fusion gene is a hallmark genomic aberration in high-risk acute iymphoblastic leukemia in infants. Although it is well established that MLL-AF4…”
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13
Stroma-derived but not tumor ADAMTS1 is a main driver of tumor growth and metastasis
Published in Oncotarget (07-06-2016)“…The matrix metalloprotease ADAMTS1 (A Disintegrin And Metalloprotease with ThromboSpondin repeats 1) has been involved in tumorigenesis although its…”
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14
Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations
Published in Pharmacogenomics (01-11-2013)“…Acute urticaria/angioedema (AUA) induced by cross-intolerance to NSAIDs is the most frequent clinical entity in hypersensitivity reactions to drugs. In this…”
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15
Inhibition of ADAMTS1 Expression by Lentiviral CRISPR/Cas9 Gene Editing Technology
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2020)“…The continuous improvement of gene editing tools has allowed a major revolution in biological sciences. Although a variety of gain and loss-of-function…”
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ADAMTS1 Contributes to the Acquisition of an Endothelial-like Phenotype in Plastic Tumor Cells
Published in Cancer research (Chicago, Ill.) (01-06-2010)“…Cancer stem cells have been hypothesized to explain tumor plasticity, including the capability to adopt distinct differentiation commitments. Among the…”
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Cataloguing the Effects of Genetic Variants in 5' Upstream Regions of Eicosanoid Related Genes
Published in Journal of allergy and clinical immunology (01-02-2015)“…Conclusions By combining molecular data from different sources we can find SNPs that affect gene expression and that are associated with immune system related…”
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Genetic Variants in Arachidonic Acid Pathway Genes Associated with Nsaids-Exacerbated Respiratory Disease
Published in Journal of allergy and clinical immunology (01-02-2015)“…[...]we have analyzed copy number variants (CNVs) for genes involved in arachidonic acid metabolism…”
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Identification of substrates of the extracellular protease ADAMTS1 by DIGE proteomic analysis
Published in Proteomics (Weinheim) (01-04-2006)“…Proteolytic modification of components of the extracellular milieu by metalloproteinases plays important roles in the regulation of multiple cellular and…”
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Gold Nanoparticle-Assisted Virus Formation by Means of the Delivery of an Oncolytic Adenovirus Genome
Published in Nanomaterials (Basel, Switzerland) (17-06-2020)“…Oncolytic adenoviruses are a therapeutic alternative to treat cancer based on their ability to replicate selectively in tumor cells. However, their use is…”
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