Search Results - "Plava, Jana"
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Recent advances in understanding tumor stroma-mediated chemoresistance in breast cancer
Published in Molecular cancer (30-03-2019)“…Although solid tumors comprise malignant cells, they also contain many different non-malignant cell types in their micro-environment. The cellular components…”
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Decreased levels of circulating cytokines VEGF, TNF-β and IL-15 indicate PD-L1 overexpression in tumours of primary breast cancer patients
Published in Scientific reports (14-01-2021)“…Programmed death ligand 1 (PD-L1) overexpression has been associated with poor clinical outcomes in several human cancers whose increased malignant behaviour…”
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ALDH1A3 upregulation and spontaneous metastasis formation is associated with acquired chemoresistance in colorectal cancer cells
Published in BMC cancer (24-08-2018)“…Efficiency of colorectal carcinoma treatment by chemotherapy is diminished as the resistance develops over time in patients. The same holds true for…”
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Rheumatoid Synovial Fluid and Acidic Extracellular pH Modulate the Immunomodulatory Activity of Urine-Derived Stem Cells
Published in International journal of molecular sciences (01-11-2023)“…Urine-derived stem cells (UdSCs) possess a remarkable anti-inflammatory and immune-modulating activity. However, the clinical significance of UdSCs in…”
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Targeting of Deregulated Wnt/β-Catenin Signaling by PRI-724 and LGK974 Inhibitors in Germ Cell Tumor Cell Lines
Published in International journal of molecular sciences (20-04-2021)“…The majority of patients with testicular germ cell tumors (GCTs) can be cured with cisplatin-based chemotherapy. However, for a subset of patients present with…”
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Chemotherapy-triggered changes in stromal compartment drive tumor invasiveness and progression of breast cancer
Published in Journal of experimental & clinical cancer research (27-09-2021)“…Chemotherapy remains a standard treatment option for breast cancer despite its toxic effects to normal tissues. However, the long-lasting effects of…”
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Increased Stromal Infiltrating Lymphocytes Are Associated with the Risk of Disease Progression in Mesenchymal Circulating Tumor Cell-Positive Primary Breast Cancer Patients
Published in International journal of molecular sciences (12-12-2020)“…Circulating tumor cells (CTCs) and the immune infiltration of tumors are closely related to clinical outcomes. This study aimed to verify the influence of…”
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Permanent Pro-Tumorigenic Shift in Adipose Tissue-Derived Mesenchymal Stromal Cells Induced by Breast Malignancy
Published in Cells (Basel, Switzerland) (19-02-2020)“…During cancer progression, breast tumor cells interact with adjacent adipose tissue, which has been shown to be engaged in cancer aggressiveness. However, the…”
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Intentionally flawed manuscripts as means for teaching students to critically evaluate scientific papers
Published in Biochemistry and molecular biology education (01-01-2018)“…As future scientists, university students need to learn how to avoid making errors in their own manuscripts, as well as how to identify flaws in papers…”
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The third dimension of tumor microenvironment—The importance of tumor stroma in 3D cancer models
Published in Experimental Biology and Medicine (01-08-2023)“…Recent advances in the three-dimensional (3D) cancer models give rise to a plethora of new possibilities in the development of anti-cancer drug therapies and…”
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The Role of BRCA1/2 -Mutated Tumor Microenvironment in Breast Cancer
Published in Cancers (02-02-2021)“…Taking into account the factors of high incidence rate, prevalence and mortality, breast cancer represents a crucial social and economic burden. Most cases of…”
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Inflammation-Based Scores Increase the Prognostic Value of Circulating Tumor Cells in Primary Breast Cancer
Published in Cancers (01-05-2020)“…A correlation between circulating tumor cells (CTCs) and monocytes in metastatic breast cancer (BC), where CTCs and monocyte-to-lymphocyte ratio (MLR) were…”
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Cytotoxic response of 5-fluorouracil-resistant cells to gene- and cell-directed enzyme/prodrug treatment
Published in Cancer gene therapy (01-12-2018)“…Gene-directed enzyme/prodrug therapy (GDEPT) mediated by mesenchymal stromal cells (MSC) was already approved for clinical study on a progressive disease…”
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Mapping and Analysis of Swi5 and Sfr1 Phosphorylation Sites
Published in Genes (30-06-2021)“…The evolutionarily conserved Swi5-Sfr1 complex plays an important role in homologous recombination, a process crucial for the maintenance of genomic integrity…”
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