Search Results - "Platt, Daniel"

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    Anatolian genetic ancestry in North Lebanese populations by Platt, Daniel E., Henschel, Andreas, Taleb, Nassim Nicholas, Zalloua, Pierre

    Published in Scientific reports (05-07-2024)
    “…Lebanon’s rich history as a cultural crossroad spanning millennia has significantly impacted the genetic composition of its population through successive waves…”
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    Observational study of factors associated with morbidity and mortality from COVID-19 in Lebanon, 2020–2021 by Nader, Moni, Zmerli, Omar, Platt, Daniel E, Hamdan, Hamdan, Hamdash, Salwa, Tayeh, Rami Abi, Azar, Jad, Kadi, Diana, Sultan, Youssef, Bazarbachi, Taha, Karayakoupoglou, Gilbert, Zalloua, Pierre, Azar, Eid

    Published in PloS one (19-10-2022)
    “…Background The COVID-19 pandemic claimed millions of lives worldwide without clear signs of abating despite several mitigation efforts and vaccination…”
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    Topology and redescriptions detect multiple alternative biological pathways from clinical phenotypes by Karisani, Negin, Platt, Daniel E, Basu, Saugata, Parida, Laxmi

    “…Biological pathways play a crucial role in the properties of diseases and are important in drug discovery. Identifying the logical relationships among…”
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    Group-invariant machine learning on the Kreuzer-Skarke dataset by Ewert, Christian, Magruder, Sumner, Maiboroda, Vera, Shen, Yueyang, Singh, Pragya, Platt, Daniel

    Published in Physics letters. B (01-11-2024)
    “…We use supervised machine learning to predict Hodge numbers for Calabi-Yau threefolds encoded by reflexive polyhedra. The Hodge number is invariant to the…”
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    Integrating Linguistics, Social Structure, and Geography to Model Genetic Diversity within India by Bose, Aritra, Platt, Daniel E, Parida, Laxmi, Drineas, Petros, Paschou, Peristera

    Published in Molecular biology and evolution (04-05-2021)
    “…Abstract India represents an intricate tapestry of population substructure shaped by geography, language, culture, and social stratification. Although…”
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    Diabetes-induced Coronary Vascular Dysfunction Involves Increased Arginase Activity by Romero, Maritza J, Platt, Daniel H, Tawfik, Huda E, Labazi, Mohamed, El-Remessy, Azza B, Bartoli, Manuela, Caldwell, Ruth B, Caldwell, Robert W

    Published in Circulation research (04-01-2008)
    “…Increases in arginase activity have been reported in a variety of disease conditions characterized by vascular dysfunction. Arginase competes with NO synthase…”
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    Lies, Gosh Darn Lies, and not enough good statistics: why epidemic model parameter estimation fails by Platt, Daniel E., Parida, Laxmi, Zalloua, Pierre

    Published in Scientific reports (11-01-2021)
    “…We sought to investigate whether epidemiological parameters that define epidemic models could be determined from the epidemic trajectory of infections,…”
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    Coronary artery disease patients with rs7904519 (TCF7L2) are at a persistent risk of type 2 diabetes by AL Hageh, Cynthia, O'Sullivan, Siobhan, Platt, Daniel E., Henschel, Andreas, Chacar, Stephanie, Gauguier, Dominique, Abchee, Antoine, Alefishat, Eman, Nader, Moni, Zalloua, Pierre A

    Published in Diabetes research and clinical practice (01-01-2024)
    “…Type 2 diabetes (T2D) and coronary artery disease (CAD) often coexist and share genetic factors.This study aimed to investigate the common genetic factors…”
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    Genome-wide diversity in the levant reveals recent structuring by culture by Haber, Marc, Gauguier, Dominique, Youhanna, Sonia, Patterson, Nick, Moorjani, Priya, Botigué, Laura R, Platt, Daniel E, Matisoo-Smith, Elizabeth, Soria-Hernanz, David F, Wells, R Spencer, Bertranpetit, Jaume, Tyler-Smith, Chris, Comas, David, Zalloua, Pierre A

    Published in PLoS genetics (01-02-2013)
    “…The Levant is a region in the Near East with an impressive record of continuous human existence and major cultural developments since the Paleolithic period…”
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    Autosomal genetics and Y-chromosome haplogroup L1b-M317 reveal Mount Lebanon Maronites as a persistently non-emigrating population by Platt, Daniel E, Artinian, Hovig, Mouzaya, Francis, Khalil, Wissam, Kamar, Francois G, Matisoo-Smith, Elizabeth, Calafell, Francesc, Taleb, Nassim Nicolas, Zalloua, Pierre

    Published in European journal of human genetics : EJHG (01-04-2021)
    “…Currently, there are 18 different religious communities living in Lebanon. While evolving primarily within Lebanon, these communities show a level of local…”
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    AI-enabled evaluation of genome-wide association relevance and polygenic risk score prediction in Alzheimer's disease by Platt, Daniel E., Guzmán-Sáenz, Aldo, Bose, Aritra, Saha, Subrata, Utro, Filippo, Parida, Laxmi

    Published in iScience (15-03-2024)
    “…GWAS focuses on significance loosing false positives; machine learning probes sub-significant features relying on predictivity. Yet, these are far from…”
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    Vascular endothelial growth factor and diabetic retinopathy: role of oxidative stress by Caldwell, Ruth B, Bartoli, Manuela, Behzadian, M Ali, El-Remessy, Azza E B, Al-Shabrawey, Mohamed, Platt, Daniel H, Liou, Gregory I, Caldwell, R William

    Published in Current drug targets (01-06-2005)
    “…Retinal neovascularization and macular edema are central features of diabetic retinopathy, a major cause of blindness in working age adults. The currently…”
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    Mapping Post-Glacial expansions: The Peopling of Southwest Asia by Platt, Daniel E., Haber, Marc, Dagher-Kharrat, Magda Bou, Douaihy, Bouchra, Khazen, Georges, Ashrafian Bonab, Maziar, Salloum, Angélique, Mouzaya, Francis, Luiselli, Donata, Tyler-Smith, Chris, Renfrew, Colin, Matisoo-Smith, Elizabeth, Zalloua, Pierre A.

    Published in Scientific reports (06-01-2017)
    “…Archaeological, palaeontological and geological evidence shows that post-glacial warming released human populations from their various climate-bound refugia…”
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    K- Mer Analyses Reveal Different Evolutionary Histories of Alpha, Beta, and Gamma Papillomaviruses by Chen, Zigui, Utro, Filippo, Platt, Daniel, DeSalle, Rob, Parida, Laxmi, Chan, Paul K S, Burk, Robert D

    “…Papillomaviruses (PVs) are a heterogeneous group of DNA viruses that can infect fish, birds, reptiles, and mammals. PVs infecting humans (HPVs)…”
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    Multiple Loci Selection with Multi-Way Epistasis in Coalescence with Recombination by Bose, Aritra, Utro, Filippo, Platt, Daniel E., Parida, Laxmi

    Published in Algorithms (2021)
    “…As studies move into deeper characterization of the impact of selection through non-neutral mutations in whole genome population genetics, modeling for…”
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