Assessment of four different cardiac softwares for evaluation of LVEF with CZT-SPECT vs CMR in 48 patients with recent STEMI

To compare, vs CMR, four softwares: quantitative gated SPECT (QGS), myometrix (MX), corridor 4DM (4DM), and Emory toolbox (ECTb) to evaluate left ventricular ejection fraction (LVEF), end-systolic (ESV), and end-diastolic volumes (EDVs) by gated MPI CZT-SPECT. 48 patients underwent MPI CZT-SPECT and...

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Bibliographic Details
Published in:	Journal of nuclear cardiology Vol. 27; no. 6; pp. 2017 - 2026
Main Authors:	Plateau, Antoine, Bouvet, Clément, Merlin, Charles, Pereira, Bruno, Barres, Bertrand, Clerfond, Guillaume, Cachin, Florent, Cassagnes, Lucie
Format:	Journal Article
Language:	English
Published:	Cham Elsevier Inc 01-12-2020 Springer International Publishing Springer Nature B.V Springer Verlag
Subjects:	Adult Aged Cadmium Cameras Cancer Cardiology Diastole Ejection fraction Electrocardiography end-diastolic volume end-systolic volume Female Gated Blood-Pool Imaging - methods Heart attacks Humans Image Processing, Computer-Assisted - instrumentation Image Processing, Computer-Assisted - methods Imaging Left ventricular ejection fraction Life Sciences Magnetic Resonance Imaging - methods Male Medicine Medicine & Public Health Middle Aged MPI CZT-SPECT NMR Nuclear magnetic resonance Nuclear Medicine Original Article Radiology Software Software packages softwares ST Elevation Myocardial Infarction - diagnostic imaging Stroke Volume Studies Technetium Tc 99m Sestamibi Tellurium Tomography, Emission-Computed, Single-Photon - methods Ventricular Dysfunction, Left Ventricular Function, Left Zinc softwares LVEF end-systolic volume CMR ESV MX 4MD ECTb Left ventricular ejection fraction EDV end-diastolic volume QGS MPI CZT-SPECT
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Summary:	To compare, vs CMR, four softwares: quantitative gated SPECT (QGS), myometrix (MX), corridor 4DM (4DM), and Emory toolbox (ECTb) to evaluate left ventricular ejection fraction (LVEF), end-systolic (ESV), and end-diastolic volumes (EDVs) by gated MPI CZT-SPECT. 48 patients underwent MPI CZT-SPECT and CMR 6 weeks after STEMI, LV parameters were measured with four softwares at MPI CZT-SPECT vs CMR. We evaluated (i) concordance and correlation between MPI CZT-SPECT and CMR, (ii) concordance MPI CZT-SPECT/CMR for the categorical evaluation of the left ventricular dysfunction, and (iii) impacts of perfusion defects > 3 segments on concordance. LVEF: LCC QGS/CMR = 0.81 [+ 2.2% (± 18%)], LCC MX/CMR = 0.83 [+ 1% (± 17.5%)], LCC 4DM/CMR = 0.73 [+ 3.9% (± 21%)], LCC ECTb/CMR = 0.69 [+ 6.6% (± 21.1%)]. ESV: LCC QGS/CMR = 0.90 [− 8 mL (± 40 mL)], LCC MX/CMR = 0.90 [− 9 mL (± 36 mL)], LCC 4DM/CMR = 0.89 [+ 4 mL (± 45 mL)], LCC ECTb/CMR = 0.87 [− 3 mL (± 45 mL)]. EDV: LCC QGS/CMR = 0.70 [− 16 mL (± 67 mL)], LCC MX/CMR = 0.68 [− 21 mL (± 63 mL], LCC 4DM/CMR = 0.72 [+ 9 mL (± 73 mL)], LCC ECTb/CMR = 0.69 [+ 10 mL (± 70 mL)]. QGS and MX were the two best-performing softwares to evaluate LVEF after recent STEMI.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23
ISSN:	1071-3581 1532-6551
DOI:	10.1007/s12350-018-01493-y