Search Results - "Plas, Gina"

The in vitro MN assay in 2011: origin and fate, biological significance, protocols, high throughput methodologies and toxicological relevance by Kirsch-Volders, Micheline, Plas, Gina, Elhajouji, Azeddine, Lukamowicz, Magdalena, Gonzalez, Laetitia, Vande Loock, Kim, Decordier, Ilse

“…Micronuclei (MN) are small, extranuclear bodies that arise in dividing cells from acentric chromosome/chromatid fragments or whole chromosomes/chromatids…”
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In vitro genotoxicity testing using the micronucleus assay in cell lines, human lymphocytes and 3D human skin models by Kirsch-Volders, Micheline, Decordier, Ilse, Elhajouji, Azeddine, Plas, Gina, Aardema, Marilyn J, Fenech, Michael

“…The toxicological relevance of the micronucleus (MN) test is well defined: it is a multi-target genotoxic endpoint, assessing not only clastogenic and…”
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Maternal and Gestational Factors and Micronucleus Frequencies in Umbilical Blood: The NewGeneris Rhea Cohort in Crete by Loock, Kim Vande, Fthenou, Eleni, Decordier, Ilse, Chalkiadaki, Georgia, Keramarou, Maria, Plas, Gina, Roelants, Mathieu, Kleinjans, Jos, Chatzi, Leda, Merlo, Franco, Kogevinas, Manolis, Kirsch-Volders, Micheline

“…Background: The use of cancer-related biomarkers in newborns has been very limited. Objective: We investigated the formation of micronuclei (MN) in full-term…”
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Automated image analysis of cytokinesis-blocked micronuclei: an adapted protocol and a validated scoring procedure for biomonitoring by Decordier, Ilse, Papine, Alexander, Plas, Gina, Roesems, Sam, Vande Loock, Kim, Moreno-Palomo, Jennifer, Cemeli, Eduardo, Anderson, Diana, Fucic, Aleksandra, Marcos, Ricardo, Soussaline, Françoise, Kirsch-Volders, Micheline

“…Micronuclei (MN) frequencies in peripheral blood lymphocytes have been used worldwide as a biomarker of chromosomal damage for genotoxicity testing and…”
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Automated image analysis of micronuclei by IMSTAR for biomonitoring by Decordier, Ilse, Papine, Alexandre, Vande Loock, Kim, Plas, Gina, Soussaline, Françoise, Kirsch-Volders, Micheline

“…For many years, the analysis of micronuclei (MN) has been successfully applied to human biomonitoring of in vivo genotoxin exposure and provides a sensitive…”
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Exploring the aneugenic and clastogenic potential in the nanosize range: A549 human lung carcinoma cells and amorphous monodisperse silica nanoparticles as models by Gonzalez, Laetitia, Thomassen, Leen C. J., Plas, Gina, Rabolli, Virginie, Napierska, Dorota, Decordier, Ilse, Roelants, Mathieu, Hoet, Peter H., Kirschhock, Christine E. A., Martens, Johan A., Lison, Dominique, Kirsch-Volders, Micheline

“…Abstract We explored how to assess the genotoxic potential of nanosize particles with a well validated assay, the in vitro cytochalasin-B micronucleus assay,…”
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Lower nucleotide excision repair capacity in newborns compared to their mothers: A pilot study by Vande Loock, Kim, Decordier, Ilse, Plas, Gina, Ciardelli, Roberta, Haumont, Dominique, Kirsch-Volders, Micheline

“…•Pilot study of 25 newborn daughters and their mothers.•Application of recent developed nucleotide excision repair phenotype assay.•Lower repair capacity…”
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Preterm newborns show slower repair of oxidative damage and paternal smoking associated DNA damage by VANDE LOOCK, Kim, CIARDELLI, Roberta, DECORDIER, Ilse, PLAS, Gina, HAUMONT, Dominique, KIRSCH-VOLDERS, Micheline

“…Newborns have to cope with hypoxia during delivery and a sudden increase in oxygen at birth. Oxygen will partly be released as reactive oxygen species having…”
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The effect of dietary estimates calculated using food frequency questionnaires on micronuclei formation in European pregnant women: a NewGeneris study by Vande Loock, Kim, Botsivali, Maria, Zangogianni, Marina, Anderson, Diana, Baumgartner, Adolph, Fthenou, Eleni, Chatzi, Leda, Marcos, Ricard, Agramunt, Sylvia, Namork, Ellen, Granum, Berit, Knudsen, Lisbeth E, Nielssen, Jeanette K S, Meltzer, Helle Margrete, Haugen, Margaretha, Kyrtopoulos, Soterios A, Decordier, Ilse, Plas, Gina, Roelants, Mathieu, Merlo, Franco, Kleinjans, Jos, Kogevinas, Manolis, Kirsch-Volders, Micheline

“…The use of biomarkers of early genetic effects, predictive for cancer, such as micronuclei (MN) in lymphocytes, may help to investigate the association between…”
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Automated image analysis of micronuclei by IMSTAR for biomonitoring: MICRONUCLEI - Recent advances in their measurement in understanding of molecular mechanisms and their association with environment genetics and disease by DECORDIER, Ilse, PAPINE, Alexandre, KIM VANDE LOOCK, PLAS, Gina, SOUSSALINE, Françoise, KIRSCH-VOLDERS, Micheline

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In vitro genotoxicity testing using the micronucleus assay in cell lines, human lymphocytes and 3D human skin models: MICRONUCLEI - Recent advances in their measurement in understanding of molecular mechanisms and their association with environment genetics and disease by KIRSCH-VOLDERS, Micheline, DECORDIER, Ilse, ELHAJOUJI, Azeddine, PLAS, Gina, AARDEMA, Marilyn J, FENECH, Michael

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Cytogenetic effects in children and mothers exposed to air pollution assessed by the frequency of micronuclei and fluorescence in situ hybridization (FISH): A family pilot study in the Czech Republic by Pedersen, Marie, Vinzents, Peter, Petersen, Joergen Holm, Kleinjans, Jos C.S., Plas, Gina, Kirsch-Volders, Micheline, Dostál, Miroslav, Rössner, Pavel, Beskid, Olena, Sram, Radim J., Merlo, Domenico Franco, Knudsen, Lisbeth Ehlert

“…A family pilot study was conducted in the Czech Republic to test the hypothesis that exposure to air pollution with particulate matter (PM) in children results…”
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