Search Results - "Planus, Emmanuelle"

Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions by Albiges-Rizo, Corinne, Destaing, Olivier, Fourcade, Bertrand, Planus, Emmanuelle, Block, Marc R

“…The invasiveness of cells is correlated with the presence of dynamic actin-rich membrane structures called invadopodia, which are membrane protrusions that are…”
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β3 integrin-mediated spreading induced by matrix-bound BMP-2 controls Smad signaling in a stiffness-independent manner by Fourel, Laure, Valat, Anne, Faurobert, Eva, Guillot, Raphael, Bourrin-Reynard, Ingrid, Ren, Kefeng, Lafanechère, Laurence, Planus, Emmanuelle, Picart, Catherine, Albiges-Rizo, Corinne

“…Understanding how cells integrate multiple signaling pathways to achieve specific cell differentiation is a challenging question in cell biology. We have…”
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Functional and structural consequences of epithelial cell invasion by Bordetella pertussis adenylate cyclase toxin by Angely, Christelle, Ladant, Daniel, Planus, Emmanuelle, Louis, Bruno, Filoche, Marcel, Chenal, Alexandre, Isabey, Daniel

“…Bordetella pertussis, the causative agent of whopping cough, produces an adenylate cyclase toxin (CyaA) that plays a key role in the host colonization by…”
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CCM2-deficient endothelial cells undergo a ROCK-dependent reprogramming into senescence-associated secretory phenotype by Vannier, Daphné Raphaëlle, Shapeti, Apeksha, Chuffart, Florent, Planus, Emmanuelle, Manet, Sandra, Rivier, Paul, Destaing, Olivier, Albiges-Rizo, Corinne, Van Oosterwyck, Hans, Faurobert, Eva

“…Cerebral cavernous malformation (CCM) is a cerebrovascular disease in which stacks of dilated haemorrhagic capillaries form focally in the brain. Whether and…”
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β1A integrin is a master regulator of invadosome organization and function by Destaing, Olivier, Planus, Emmanuelle, Bouvard, Daniel, Oddou, Christiane, Badowski, Cedric, Bossy, Valentine, Raducanu, Aurelia, Fourcade, Bertrand, Albiges-Rizo, Corinne, Block, Marc R

“…Invadosomes are adhesion structures involved in tissue invasion that are characterized by an intense actin polymerization-depolymerization associated with β1…”
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ICAP-1 monoubiquitylation coordinates matrix density and rigidity sensing for cell migration through ROCK2-MRCKα balance by Bouin, Anne-Pascale, Kyumurkov, Alexander, Régent-Kloeckner, Myriam, Ribba, Anne-Sophie, Faurobert, Eva, Fournier, Henri-Noël, Bourrin-Reynard, Ingrid, Manet-Dupé, Sandra, Oddou, Christiane, Balland, Martial, Planus, Emmanuelle, Albiges-Rizo, Corinne

“…Cell migration is a complex process requiring density and rigidity sensing of the microenvironment to adapt cell migratory speed through focal adhesion and…”
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Extracellular matrix rigidity controls podosome induction in microvascular endothelial cells by Juin, Amélie, Planus, Emmanuelle, Guillemot, Fabien, Horakova, Petra, Albiges-Rizo, Corinne, Génot, Elisabeth, Rosenbaum, Jean, Moreau, Violaine, Saltel, Frédéric

“…Background information Podosomes are actin‐based structures involved in cell adhesion, migration, invasion and extracellular matrix degradation. They have been…”
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Correction: ICAP-1 monoubiquitylation coordinates matrix density and rigidity sensing for cell migration through ROCK2-MRCKα balance by Bouin, Anne-Pascale, Kyumurkov, Alexander, Régent-Kloeckner, Myriam, Ribba, Anne-Sophie, Faurobert, Eva, Fournier, Henri-Noël, Bourrin-Reynard, Ingrid, Manet-Dupé, Sandra, Oddou, Christiane, Balland, Martial, Planus, Emmanuelle, Albiges-Rizo, Corinne

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Spatiotemporal dynamics of actin-rich adhesion microdomains: influence of substrate flexibility by Collin, Olivier, Tracqui, Philippe, Stephanou, Angélique, Usson, Yves, Clément-Lacroix, Jocelyne, Planus, Emmanuelle

“…In this study we analyse the formation and dynamics of specific actin-rich structures called podosomes. Podosomes are very dynamic punctual adhesion sites…”
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Partitioning of cortical and deep cytoskeleton responses from transient magnetic bead twisting by Laurent, Valérie M, Fodil, Redouane, Cañadas, Patrick, Féréol, Sophie, Louis, Bruno, Planus, Emmanuelle, Isabey, Daniel

“…We attempted to estimate in living adherent epithelial alveolar cells, the degree of structural and mechanical heterogeneity by considering two individualized…”
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Keratinocyte growth factor promotes cell motility during alveolar epithelial repair in vitro by Galiacy, Stéphane, Planus, Emmanuelle, Lepetit, Hélène, Féréol, Sophie, Laurent, Valérie, Ware, Lorraine, Isabey, Daniel, Matthay, Michael, Harf, Alain, d’Ortho, Marie-Pia

“…Epithelia play a key role as protective barriers, and mechanisms of repair are crucial for restoring epithelial barrier integrity, especially in the lung. Cell…”
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Role of collagenase in mediating in vitro alveolar epithelial wound repair by Planus, E, Galiacy, S, Matthay, M, Laurent, V, Gavrilovic, J, Murphy, G, Clérici, C, Isabey, D, Lafuma, C, d'Ortho, M P

“…Type II pneumocytes are essential for repair of the injured alveolar epithelium. The effect of two MMP collagenases, MMP-1 and MMP-13 on alveolar epithelial…”
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Negative impact of DEP exposure on human airway epithelial cell adhesion, stiffness, and repair by Doornaert, Blandine, Leblond, Valerie, Galiacy, Stephane, Gras, Gabriel, Planus, Emmanuelle, Laurent, Valerie, Isabey, Daniel, Lafuma, Chantal

“…Epidemiological and experimental studies suggest that diesel exhaust particles (DEPs) may be associated with increased respiratory mortality and morbidity…”
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Invadosome regulation by adhesion signaling by Destaing, Olivier, Block, Marc R, Planus, Emmanuelle, Albiges-Rizo, Corinne

“…Highlights ► Invadosome assembly is promoted by extracellular matrix signaling. ► Invadosomes sense the mechano-chemical properties of extracellular matrix. ►…”
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Force tuning through regulation of clathrin-dependent integrin endocytosis by Kyumurkov, Alexander, Bouin, Anne-Pascale, Boissan, Mathieu, Manet, Sandra, Baschieri, Francesco, Proponnet-Guerault, Mathilde, Balland, Martial, Destaing, Olivier, Régent-Kloeckner, Myriam, Calmel, Claire, Nicolas, Alice, Waharte, François, Chavrier, Philippe, Montagnac, Guillaume, Planus, Emmanuelle, Albiges-Rizo, Corinne

“…Integrin endocytosis is essential for many fundamental cellular processes. Whether and how the internalization impacts cellular mechanics remains elusive…”
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Matrix metalloproteinase gelatinases in sulfur mustard-induced acute airway injury in guinea pigs by Calvet, J H, Planus, E, Rouet, P, Pezet, S, Levame, M, Lafuma, C, Harf, A, D'Ortho, M P

“…Respiratory tract lesions induced by sulfur mustard (SM), a chemical warfare agent, are characterized by epithelial damage associated with inflammatory cell…”
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Force tuning through regulation of clathrin-dependent integrin endocytosis by Kyumurkov, Alexander, Bouin, Anne-Pascale, Boissan, Mathieu, Manet, Sandra, Baschieri, Francesco, Proponnet-Guerault, Mathilde, Balland, Martial, Destaing, Olivier, Régent-Kloeckner, Myriam, Calmel, Claire, Nicolas, Alice, Waharte, François, Chavrier, Philippe, Montagnac, Guillaume, Planus, Emmanuelle, Albiges-Rizo, Corinne

“…Integrin endocytosis is essential for many fundamental cellular processes. Whether and how the internalization impacts cellular mechanics remains elusive…”
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The CCM1-CCM2 complex controls complementary functions of ROCK1 and ROCK2 that are required for endothelial integrity by Lisowska, Justyna, Rödel, Claudia Jasmin, Manet, Sandra, Miroshnikova, Yekaterina A, Boyault, Cyril, Planus, Emmanuelle, De Mets, Richard, Lee, Hsiao-Hui, Destaing, Olivier, Mertani, Hichem, Boulday, Gwénola, Tournier-Lasserve, Elisabeth, Balland, Martial, Abdelilah-Seyfried, Salim, Albiges-Rizo, Corinne, Faurobert, Eva

“…Endothelial integrity relies on a mechanical crosstalk between intercellular and cell-matrix interactions. This crosstalk is compromised in hemorrhagic…”
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Evidence of a non-conventional role for the urokinase tripartite complex (uPAR/uPA/PAI-1) in myogenic cell fusion by Bonavaud, S, Charrière-Bertrand, C, Rey, C, Leibovitch, M P, Pedersen, N, Frisdal, E, Planus, E, Blasi, F, Gherardi, R, Barlovatz-Meimon, G

“…Urokinase can form a tripartite complex binding urokinase receptor (uPAR) and plasminogen activator inhibitor type-1 (PAI-1), a component of the extracellular…”
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Podosome-type adhesions and focal adhesions, so alike yet so different by Block, Marc R, Badowski, Cedric, Millon-Fremillon, Angelique, Bouvard, Daniel, Bouin, Anne-Pascale, Faurobert, Eva, Gerber-Scokaert, Delphine, Planus, Emmanuelle, Albiges-Rizo, Corinne

“…Cell-matrix adhesions are essential for cell migration, tissue organization and differentiation, therefore playing central roles in embryonic development,…”
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