Search Results - "Plano, Andrea"

Abnormal cognition, sleep, EEG and brain metabolism in a novel knock-in Alzheimer mouse, PLB1 by Platt, Bettina, Drever, Benjamin, Koss, David, Stoppelkamp, Sandra, Jyoti, Amar, Plano, Andrea, Utan, Aneli, Merrick, Georgina, Ryan, Duncan, Melis, Valeria, Wan, Hong, Mingarelli, Marco, Porcu, Emanuele, Scrocchi, Louise, Welch, Andy, Riedel, Gernot

“…Late-stage neuropathological hallmarks of Alzheimer's disease (AD) are β-amyloid (βA) and hyperphosphorylated tau peptides, aggregated into plaques and…”
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Quantitative electroencephalography parameters as neurophysiological biomarkers of schizophrenia-related deficits: A Phase II substudy of patients treated with iclepertin (BI 425809) by Schultheis, Christian, Rosenbrock, Holger, Mack, Salome Rebecca, Vinisko, Richard, Schuelert, Niklas, Plano, Andrea, Süssmuth, Sigurd D.

“…Patients with schizophrenia experience cognitive impairment related to neural network dysfunction and deficits in sensory processing. These deficits are…”
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Modulation of food consumption and sleep–wake cycle in mice by the neutral CB1 antagonist ABD459 by Goonawardena, Anushka V, Plano, Andrea, Robinson, Lianne, Ross, Ruth, Greig, Iain, Pertwee, Roger G, Hampson, Robert E, Platt, Bettina, Riedel, Gernot

“…The brain endocannabinoid system is a potential target for the treatment of psychiatric and metabolic conditions. Here, a novel CB1 receptor antagonist…”
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P285. Pharmacological Effects of the Novel NR2B Modulator Bi 1569912 on Electroencephalography and Eye-Tracking in a Phase I Study by Schultheis, Christian, Hoch, Anja, Just, Stefan, Plano, Andrea

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Electroencephalography as a Clinical Biomarker in a Phase II Substudy With BI 425809 in Patients With Schizophrenia by Rosenbrock, Holger, Schultheis, Christian, Mack, Salome Rebecca, Vinisko, Richard, Schuelert, Niklas, Plano, Andrea, Suessmuth, Sigurd

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Progressive age-related changes in sleep and EEG profiles in the PLB1Triple mouse model of Alzheimer’s disease by Jyoti, Amar, Plano, Andrea, Riedel, Gernot, Platt, Bettina

“…Abstract Sleep disturbances are common in Alzheimer’s disease (AD) and now assumed to contribute to disease onset and progression. Here, we investigated…”
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Differential effects of traxoprodil and S-ketamine on quantitative EEG and auditory event-related potentials as translational biomarkers in preclinical trials in rats and mice by Raith, Henrike, Schuelert, Niklas, Duveau, Venceslas, Roucard, Corinne, Plano, Andrea, Dorner-Ciossek, Cornelia, Ferger, Boris

“…Quantitative Electroencephalography (qEEG) and event-related potential (ERP) assessment have emerged as powerful tools to unravel translational biomarkers in…”
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Long-term home cage activity scans reveal lowered exploratory behaviour in symptomatic female Rett mice by Robinson, Lianne, Plano, Andrea, Cobb, Stuart, Riedel, Gernot

“…•Mecp2Stop mutant female mice develop Rett-like symptoms late in life (>6 months).•Symptoms include anomalies in motor, activity and anxiety profiles and were…”
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On the identification of sleep stages in mouse electroencephalography time-series by Lampert, Thomas, Plano, Andrea, Austin, Jim, Platt, Bettina

“…•Multiple classifiers contribute to increased detection reliability.•Experimentally optimal parameter values (e.g. epoch length) are derived.•We achieve…”
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Inference of Granger causal time-dependent influences in noisy multivariate time series by Sommerlade, Linda, Thiel, Marco, Platt, Bettina, Plano, Andrea, Riedel, Gernot, Grebogi, Celso, Timmer, Jens, Schelter, Björn

“…► Estimation of non-stationary Granger causal influences in noisy data. ► Time-resolved renormalized partial directed coherence using state space models. ►…”
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The after-hours circadian mutant has reduced phenotypic plasticity in behaviors at multiple timescales and in sleep homeostasis by Maggi, Silvia, Balzani, Edoardo, Lassi, Glenda, Garcia-Garcia, Celina, Plano, Andrea, Espinoza, Stefano, Mus, Liudmila, Tinarelli, Federico, Nolan, Patrick M., Gainetdinov, Raul R., Balci, Fuat, Nieus, Thierry, Tucci, Valter

“…Circadian clock is known to adapt to environmental changes and can significantly influence cognitive and physiological functions. In this work, we report…”
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EEG, activity, and sleep architecture in a transgenic AβPPswe/PSEN1A246E Alzheimer's disease mouse by Jyoti, Amar, Plano, Andrea, Riedel, Gernot, Platt, Bettina

“…Since sleep and electroencephalogram (EEG) disturbances are endophenotypes of Alzheimer's disease (AD) patients alongside cognitive dysfunction, we here…”
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P4‐018: EEG, activity and sleep architecture in a transgenic APP/PSEN mouse by Jyoti, Amar, Plano, Andrea, Riedel, Gernot, Platt, Bettina

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EEG, activity and sleep architecture in a transgenic APP/PSEN mouse by Jyoti, Amar, Plano, Andrea, Riedel, Gernot, Platt, Bettina

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The first third-generation Alzheimer mouse, PLB1: EEG and activity behaviour by Plano, Andrea, Jyoti, Amar, Wan, Hong, Reinhart, Peter, Riedel, Gernot, Platt, Bettina

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P4‐020: The first third‐generation Alzheimer mouse, PLB1: EEG and activity behaviour by Plano, Andrea, Jyoti, Amar, Wan, Hong, Reinhart, Peter, Riedel, Gernot, Platt, Bettina

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A Pilot Study into the Effects of the CB1 Cannabinoid Receptor Agonist WIN55,212-2 or the Antagonist/Inverse Agonist AM251 on Sleep in Rats by Robinson, Lianne, Goonawardena, Anushka V., Riedel, Gernot, Hampson, Robert E., Platt, Bettina, Plano, Andrea

“…The plant cannabinoid Δ9-tetrahydrocannabinol and the endocannabinoid anandamide increase the amount of sleep via a CB1 receptor mediated mechanism. Here, we…”
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Multivariate analysis of dynamical processes with applications to the neurosciences by Schelter, B., Sommerlade, L., Platt, B., Plano, A., Thiel, M., Timmer, J.

“…Nowadays, data are recorded with increasing spatial and temporal resolution. Commonly these data are analyzed using univariate or bivariate approaches. Most of…”
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