Search Results - "Planel, E."

Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar by Jevtovic-Todorovic, V, Absalom, A.R., Blomgren, K, Brambrink, A, Crosby, G, Culley, D.J., Fiskum, G, Giffard, R.G., Herold, K.F., Loepke, A.W., Ma, D, Orser, B.A., Planel, E, Slikker, W, Soriano, S.G., Stratmann, G, Vutskits, L, Xie, Z, Hemmings, H.C.

“…Although previously considered entirely reversible, general anaesthesia is now being viewed as a potentially significant risk to cognitive performance at both…”
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Crocin, a natural molecule with potentially beneficial effects against skin ageing by Fagot, D., Pham, D. M., Laboureau, J., Planel, E., Guerin, L., Nègre, C., Donovan, M., Bernard, B. A.

“…Objective Oxidative stress and low‐grade chronic inflammation stand out as key features of physiological skin ageing. The aim of this study was to examine in…”
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Validation of a predictive method for sunscreen formula evaluation using gene expression analysis in a Chinese reconstructed full‐thickness skin model by Liu, Y., Wang, R., He, X., Dai, H., Betts, R. J., Marionnet, C., Bernerd, F., Planel, E., Wang, X., Nocairi, H., Cai, Z., Qiu, J., Ding, C.

“…Objective This study aimed to establish a predictive in vitro method for assessing the photoprotective properties of sunscreens using a reconstructed…”
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Hypothermia and Alzheimer's disease neuropathogenic pathways by Whittington, R A, Papon, M-A, Chouinard, F, Planel, E

“…Alzheimer's disease (AD) remains a major health problem, and accounts for 50 to 60% of all cases of dementia. The two histopathological hallmarks of AD are…”
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Tau aggregates: toxic, inert, or protective species? by Bretteville, Alexis, Planel, Emmanuel

“…Alzheimer's disease brains are characterized by extracellular aggregates of the amyloid-beta peptide and intracellular neurofibrillary tangles, composed of…”
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517 Crocin, a promising molecule to prevent skin-aging processes by Fagot, D., Pham, D., Laboureau, J., Planel, E., Guerin, L., Negre, C., Donovan, M., Bernard, B.A.

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Inhibition of Glycogen Synthase Kinase-3 by Lithium Correlates with Reduced Tauopathy and Degeneration in vivo by Noble, Wendy, Planel, Emmanuel, Zehr, Cindy, Olm, Vicki, Meyerson, Jordana, Suleman, Farhana, Gaynor, Kate, Wang, Lili, LaFrancois, John, Feinstein, Boris, Burns, Mark, Krishnamurthy, Pavan, Wen, Yi, Bhat, Ratan, Lewis, Jada, Dickson, Dennis, Duff, Karen, Iversen, L. L.

“…Neurofibrillary tangles composed of hyperphosphorylated, aggregated tau are a common pathological feature of tauopathies, including Alzheimer's disease…”
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Alterations in Glucose Metabolism Induce Hypothermia Leading to Tau Hyperphosphorylation through Differential Inhibition of Kinase and Phosphatase Activities: Implications for Alzheimer's Disease by Planel, Emmanuel, Miyasaka, Tomohiro, Launey, Thomas, Chui, De-Hua, Tanemura, Kentaro, Sato, Shinji, Murayama, Ohoshi, Ishiguro, Koichi, Tatebayashi, Yoshitaka, Takashima, Akihiko

“…Alzheimer's disease (AD) brains contain neurofibrillary tangles (NFTs) composed of abnormally hyperphosphorylated tau protein. Regional reductions in cerebral…”
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Untangling memory deficits by Duff, Karen, Planel, Emmanuel

“…The buildup of protein aggregates consisting of proteins such as tau, huntingtin and amyloid- beta occurs in a range of degenerative disorders. Recent studies…”
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Inhibition of Protein Phosphatase 2A Overrides Tau Protein Kinase I/Glycogen Synthase Kinase 3β and Cyclin-dependent Kinase 5 Inhibition and Results in Tau Hyperphosphorylation in the Hippocampus of Starved Mouse by Planel, Emmanuel, Yasutake, Kaori, Fujita, Shinobu C., Ishiguro, Koichi

“…Hyperphosphorylated tau is the major component of paired helical filaments in neurofibrillary tangles found in Alzheimer's disease (AD) brain. Starvation of…”
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Tau Filament Formation and Associative Memory Deficit in Aged Mice Expressing Mutant (R406W) Human Tau by Tatebayashi, Yoshitaka, Miyasaka, Tomohiro, Chui, De-Hua, Akagi, Takumi, Mishima, Ken-ichi, Iwasaki, Katsunori, Fujiwara, Michihiro, Tanemura, Kentaro, Murayama, Miyuki, Ishiguro, Koichi, Planel, Emmanuel, Sato, Shinji, Hashikawa, Tsutomu, Takashima, Akihiko

“…The R406W tau mutation found in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) causes a hereditary tauopathy clinically resembling…”
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U‐box protein carboxyl terminus of Hsc70‐interacting protein (CHIP) mediates poly‐ubiquitylation preferentially on four‐repeat Tau and is involved in neurodegeneration of tauopathy by Hatakeyama, Shigetsugu, Matsumoto, Masaki, Kamura, Takumi, Murayama, Miyuki, Chui, Du‐Hua, Planel, Emmanuel, Takahashi, Ryosuke, Nakayama, Keiichi I., Takashima, Akihiko

“…Neurofibrillary tangles (NFTs), which are composed of hyperphosphorylated and ubiquitylated tau, are exhibited at regions where neuronal loss occurs in…”
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Aberrant Tau Phosphorylation by Glycogen Synthase Kinase-3β and JNK3 Induces Oligomeric Tau Fibrils in COS-7 Cells by Sato, Shinji, Tatebayashi, Yoshitaka, Akagi, Takumi, Chui, De-Hua, Murayama, Miyuki, Miyasaka, Tomohiro, Planel, Emmanuel, Tanemura, Kentaro, Sun, Xiaoyan, Hashikawa, Tsutomu, Yoshioka, Katsuji, Ishiguro, Koichi, Takashima, Akihiko

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Starvation induces tau hyperphosphorylation in mouse brain: implications for Alzheimer’s disease by Yanagisawa, Masahiro, Planel, Emmanuel, Ishiguro, Koichi, Fujita, Shinobu C

“…Hyperphosphorylated tau is the major component of paired helical filaments in neurofibrillary tangles found in Alzheimer’s disease brains, and tau…”
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Role of GSK-3β in Alzheimer's disease pathology by Planel, Emmanuel, Sun, Xiaoyan, Takashima, Akihiko

“…Glycogen synthase kinase 3β (GSK‐3β) is an important regulatory kinase involved in multiple processes such as metabolic control, embryonic development, cell…”
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c-jun N-terminal kinase hyperphosphorylates R406W tau at the PHF-1 site during mitosis by Tatebayashi, Yoshitaka, Planel, Emmanuel, Chui, De-Hua, Sato, Shinji, Miyasaka, Tomohiro, Sahara, Naruhiko, Murayama, Miyuki, Kikuchi, Naomi, Yoshioka, Katsuji, Rivka, Ravid, Takashima, Akihiko

“…ABSTRACT Tauopathies such as Alzheimer disease (AD) probably involve a type of phosphorylation imbalance causing the accumulation of abnormally…”
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P3-245 Participation of GSK-3beta in neurodegeneration by Cui, Dehua, Yoshiike, Y., Park, J.M., Jin, Y.L., Murayama, M., Planel, E., Tatebayashi, Y., Takashima, A.

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Aberrant Tau Phosphorylation by Glycogen Synthase Kinase-3[beta] and JNK3 Induces Oligomeric Tau Fibrils in COS-7 Cells by Sato, S, Tatebayashi, Y, Akagi, T, Chui, D, Murayama, M, Miyasaka, T, Planel, E, Tanemura, K, Sun, X, Hashikawa, T, Yoshioka, K, Ishiguro, K, Takashima, A

“…Neurofibrillary tangles (NFTs) are found in a wide range of neurodegenerative disorders, including Alzheimer's disease. The major component of NFTs is…”
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