Search Results - "Planas, Antoni"
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Substrate Recognition and Specificity of Chitin Deacetylases and Related Family 4 Carbohydrate Esterases
Published in International journal of molecular sciences (30-01-2018)“…Carbohydrate esterases family 4 (CE4 enzymes) includes chitin and peptidoglycan deacetylases, acetylxylan esterases, and poly- -acetylglucosamine deacetylases…”
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Screening Assay for Directed Evolution of Chitin Deacetylases: Application to Vibrio cholerae Deacetylase Mutant Libraries for Engineered Specificity
Published in Analytical chemistry (Washington) (18-09-2018)“…Not only the degree of acetylation but also the pattern of acetylation of chitosans and chitooligosaccharides (COS) appear to be critical for their biological…”
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Chitin Deacetylases: Structures, Specificities, and Biotech Applications
Published in Polymers (22-03-2018)“…Depolymerization and de- -acetylation of chitin by chitinases and deacetylases generates a series of derivatives including chitosans and chitooligosaccharides…”
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Characterization of a Glycolipid Synthase Producing α-Galactosylceramide in Bacteroides fragilis
Published in International journal of molecular sciences (12-11-2022)“…Glycolipids are complex molecules involved in important cellular processes. Among them, the glycosphingolipid α-galactosylceramide has proven to be of interest…”
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Transglycosylation Activity of Engineered Bifidobacterium Lacto- N -Biosidase Mutants at Donor Subsites for Lacto- N -Tetraose Synthesis
Published in International journal of molecular sciences (22-03-2021)“…The health benefits of human milk oligosaccharides (HMOs) make them attractive targets as supplements for infant formula milks. However, HMO synthesis is still…”
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Developing a single-stage continuous process strategy for vitamin B12 production with Propionibacterium freudenreichii
Published in Microbial cell factories (09-02-2023)“…Abstract Background Vitamin B 12 is a widely used compound in the feed and food, healthcare and medical industries that can only be produced by fermentation…”
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Essential Mycoplasma Glycolipid Synthase Adheres to the Cell Membrane by Means of an Amphipathic Helix
Published in Scientific reports (08-05-2019)“…Because of the lack of cell wall, Micoplasma species require a fine control of membrane fluidity and integrity. mg517 is an essential gene of Mycoplasma…”
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Engineering of a chitin deacetylase to generate tailor-made chitosan polymers
Published in PLoS biology (18-01-2024)“…Chitin deacetylases (CDAs) emerge as a valuable tool to produce chitosans with a nonrandom distribution of N-acetylglucosamine (GlcNAc) and glucosamine (GlcN)…”
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In vitro synthesis of artificial polysaccharides by glycosidases and glycosynthases
Published in Carbohydrate research (03-09-2007)“…Artificial polysaccharides produced by in vitro enzymatic synthesis are new biomaterials with defined structures that either mimic natural polysaccharides or…”
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Bioprocess Strategies for Vitamin B12 Production by Microbial Fermentation and Its Market Applications
Published in Bioengineering (Basel) (04-08-2022)“…Vitamin B12 is a widely used compound in the feed and food, healthcare and medical industries that can only be produced by fermentation because of the…”
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Structural Basis of Chitin Oligosaccharide Deacetylation
Published in Angewandte Chemie International Edition (01-07-2014)“…Cell signaling and other biological activities of chitooligosaccharides (COSs) seem to be dependent not only on the degree of polymerization, but markedly on…”
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Indolyl Septanoside Synthesis for In Vivo Screening of Bacterial Septanoside Hydrolases
Published in International journal of molecular sciences (26-04-2021)“…Building-up and breaking-down of carbohydrates are processes common to all forms of life. Glycoside hydrolases are a broad class of enzymes that play a central…”
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Preparative Scale Production of Recombinant Human Transthyretin for Biophysical Studies of Protein-Ligand and Protein-Protein Interactions
Published in International journal of molecular sciences (17-12-2020)“…Human transthyretin (hTTR), a serum protein with a main role in transporting thyroid hormones and retinol through binding to the retinol-binding protein, is an…”
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Structure-function relationships underlying the dual N-acetylmuramic and N-acetylglucosamine specificities of the bacterial peptidoglycan deacetylase PdaC
Published in The Journal of biological chemistry (13-12-2019)“…Bacillus subtilis PdaC (BsPdaC) is a membrane-bound, multidomain peptidoglycan N-deacetylase acting on N-acetylmuramic acid (MurNAc) residues and conferring…”
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Expanding the chitin oligosaccharide portfolio by engineering NodC chitin synthases in Escherichia coli
Published in Current research in biotechnology (2024)“…[Display omitted] •For the first time reported, chitinheptaose was produced using a rhizobial chitin oligosaccharide synthase.•The in vivo…”
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Structural-Functional Analysis Reveals a Specific Domain Organization in Family GH20 Hexosaminidases
Published in PloS one (29-05-2015)“…Hexosaminidases are involved in important biological processes catalyzing the hydrolysis of N-acetyl-hexosaminyl residues in glycosaminoglycans and…”
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Analysis of the injuries and workload evolution using the RPE and s-RPE method in basketball
Published in Apunts sports medicine (01-01-2022)“…The quantification of training loads provides valuable information to reduce overtraining and detecting the risk of injury. The present study looks into the…”
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Formation of a Covalent Glycosyl-Enzyme Species in a Retaining Glycosyltransferase
Published in Chemistry : a European journal (11-10-2013)“…Elusive glycosyl–enzyme adduct: Using classical MD simulations and QM/MM metadynamics, the long‐time sought glycosyl–enzyme covalent intermediate of a…”
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Chemical Rescue of α3-Galactosyltransferase. Implications in the Mechanism of Retaining Glycosyltransferases
Published in Journal of the American Chemical Society (20-12-2006)“…The mechanism of retaining glycosyltransferases is still poorly understood and the subject of current debate. Both double displacement and front side single…”
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Integrative structure determination reveals functional global flexibility for an ultra-multimodular arabinanase
Published in Communications biology (16-05-2022)“…AbnA is an extracellular GH43 α-L-arabinanase from Geobacillus stearothermophilus , a key bacterial enzyme in the degradation and utilization of arabinan. We…”
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