Search Results - "Plançon, Sébastien"

Secretion of the Phosphorylated Form of S100A9 from Neutrophils Is Essential for the Proinflammatory Functions of Extracellular S100A8/A9 by Schenten, Véronique, Plançon, Sébastien, Jung, Nicolas, Hann, Justine, Bueb, Jean-Luc, Bréchard, Sabrina, Tschirhart, Eric J, Tolle, Fabrice

“…S100A8 and S100A9 are members of the S100 family of cytoplasmic EF-hand Ca -binding proteins and are abundantly expressed in the cytosol of neutrophils. In…”
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Role of S100A8/A9 for Cytokine Secretion, Revealed in Neutrophils Derived from ER-Hoxb8 Progenitors by Zhou, Yang, Hann, Justine, Schenten, Véronique, Plançon, Sébastien, Bueb, Jean-Luc, Tolle, Fabrice, Bréchard, Sabrina

“…S100A9, a Ca2+-binding protein, is tightly associated to neutrophil pro-inflammatory functions when forming a heterodimer with its S100A8 partner. Upon…”
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An essential role of syntaxin 3 protein for granule exocytosis and secretion of IL‐1α, IL‐1β, IL‐12b, and CCL4 from differentiated HL‐60 cells by Naegelen, Isabelle, Plancon, Se´bastien, Nicot, Nathalie, Kaoma, Tony, Muller, Arnaud, Vallar, Laurent, Tschirhart, Eric J., Bre´chard, Sabrina

“…STX3 regulates the secretion of IL1α, IL1β, IL12b, and CCL4 during gelatinase degranulation in differentiated HL‐60 cells. Besides their roles in the killing…”
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Regulation of Neutrophil Degranulation and Cytokine Secretion: A Novel Model Approach Based on Linear Fitting by Tschirhart, Eric J., Schenten, Véronique, Plançon, Sébastien, Beaume, Nicolas, Naegelen, Isabelle, Bréchard, Sabrina

“…Neutrophils participate in the maintenance of host integrity by releasing various cytotoxic proteins during degranulation. Due to recent advances, a major role…”
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iPLA2, a novel determinant in Ca2+- and phosphorylation-dependent S100A8/A9 regulated NOX2 activity by Schenten, Véronique, Bréchard, Sabrina, Plançon, Sébastien, Melchior, Chantal, Frippiat, Jean-Pol, Tschirhart, Eric J.

“…The neutrophil NADPH oxidase (NOX2) is a key enzyme responsible for host defense against invading pathogens, via the production of reactive oxygen species…”
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New insights into the regulation of neutrophil NADPH oxidase activity in the phagosome: a focus on the role of lipid and Ca(2+) signaling by Bréchard, Sabrina, Plançon, Sébastien, Tschirhart, Eric J

“…Reactive oxygen species, produced by the phagosomal NADPH oxidase of neutrophils, play a significant physiological role during normal defense. Their role is…”
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ILK as a potential marker gene to ascertain specific adenocarcinoma cell mRNA isolation from frozen prostate biopsy tissue sections by Kieffer, Nelly, Schmitz, Martine, Plançon, Sébastien, Margue, Christiane, Huselstein, Fanny, Grignard, Gérard, Dippel, Walter, Nathan, Michel, Giacchi, Sandro, Scheiden, René

“…A major technical challenge related to gene expression profiling of tissue samples is the difficulty of procuring selected cell populations from tissues that…”
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A New Functional Role of the Fibrinogen RGD Motif as the Molecular Switch That Selectively Triggers Integrin αIIbβ3-dependent RhoA Activation during Cell Spreading by Salsmann, Alexandre, Schaffner-Reckinger, Elisabeth, Kabile, Fabrice, Plançon, Sébastien, Kieffer, Nelly

“…A number of RGD-type integrins rely on a synergistic site in addition to the canonical RGD site for ligand binding and signaling, although it is still unclear…”
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Corrigendum to “iPLA2, a novel determinant in Ca2+- and phosphorylation-dependent S100A8/A9 regulated NOX2 activity” [Biochim. Biophys. Acta 1803 (2010) 840–847] by Schenten, Véronique, Bréchard, Sabrina, Plançon, Sébastien, Melchior, Chantal, Frippiat, Jean-Pol, Tschirhart, Eric J.

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A Fluorescence Cell Biology Approach to Map the Second Integrin-binding Site of Talin to a 130-Amino Acid Sequence within the Rod Domain by Tremuth, Laurent, Kreis, Stephanie, Melchior, Chantal, Hoebeke, Johan, Rondé, Philippe, Plançon, Sébastien, Takeda, Kenneth, Kieffer, Nelly

“…The cytoskeletal protein talin, which provides a direct link between integrins and actin filaments, has been shown to contain two distinct binding sites for…”
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Distinct Involvement of β3 Integrin Cytoplasmic Domain Tyrosine Residues 747 and 759 in Integrin-mediated Cytoskeletal Assembly and Phosphotyrosine Signaling by Schaffner-Reckinger, Elisabeth, Gouon, Valérie, Melchior, Chantal, Plançon, Sébastien, Kieffer, Nelly

“…We have investigated the structural requirements of the β3 integrin subunit cytoplasmic domain necessary for tyrosine phosphorylation of focal adhesion kinase…”
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A new functional role of the fibrinogen RGD motif as the molecular switch that selectively triggers integrin alphaIIbbeta3-dependent RhoA activation during cell spreading by Salsmann, Alexandre, Schaffner-Reckinger, Elisabeth, Kabile, Fabrice, Plançon, Sébastien, Kieffer, Nelly

“…A number of RGD-type integrins rely on a synergistic site in addition to the canonical RGD site for ligand binding and signaling, although it is still unclear…”
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Green fluorescent protein (GFP) tagged to the cytoplasmic tail of αIIb or β3 allows the expression of a fully functional integrin αIIbβ3: effect of β3GFP on αIIbβ3 ligand binding by PLANÇON, Sébastien, MOREL-KOPP, Marie-Christine, SCHAFFNER-RECKINGER, Elisabeth, CHEN, Ping, KIEFFER, Nelly

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Green fluorescent protein (GFP) tagged to the cytoplasmic tail of αIIb or β3 allows the expression of a fully functional integrin αIIbβ3: effect of β3GFP on αIIbβ3 ligand binding by PLANÇON, Sébastien, MOREL-KOPP, Marie-Christine, SCHAFFNER-RECKINGER, Elisabeth, CHEN, Ping, KIEFFER, Nelly

“…Using green fluorescent protein (GFP) as an autofluorescent tag, we report the first successful visualization of a β3 integrin in a living cell. GFP fused in…”
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Divalent Cations Differentially Regulate Integrin αIIb Cytoplasmic Tail Binding to β3 and to Calcium- and Integrin-binding Protein by Vallar, Laurent, Melchior, Chantal, Plançon, Sébastien, Drobecq, Hervé, Lippens, Guy, Regnault, Véronique, Kieffer, Nelly

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The Novel S527F Mutation in the Integrin β3 Chain Induces a High Affinity αIIbβ3 Receptor by Hindering Adoption of the Bent Conformation by Vanhoorelbeke, Karen, De Meyer, Simon F., Pareyn, Inge, Melchior, Chantal, Plançon, Sebastien, Margue, Christiane, Pradier, Olivier, Fondu, Pierre, Kieffer, Nelly, Springer, Timothy A., Deckmyn, Hans

“…Three heterozygous mutations were identified in the genes encoding platelet integrin receptor αIIbβ3 in a patient with an ill defined platelet disorder: one in…”
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The novel S527F mutation in the integrin beta3 chain induces a high affinity alphaIIbbeta3 receptor by hindering adoption of the bent conformation by Vanhoorelbeke, Karen, De Meyer, Simon F, Pareyn, Inge, Melchior, Chantal, Plançon, Sebastien, Margue, Christiane, Pradier, Olivier, Fondu, Pierre, Kieffer, Nelly, Springer, Timothy A, Deckmyn, Hans

“…Three heterozygous mutations were identified in the genes encoding platelet integrin receptor alphaIIbbeta3 in a patient with an ill defined platelet disorder:…”
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The Novel S527F Mutation in the Integrin {beta}3 Chain Induces a High Affinity {alpha}IIb{beta}3 Receptor by Hindering Adoption of the Bent Conformation by Vanhoorelbeke, Karen, De Meyer, Simon F, Pareyn, Inge, Melchior, Chantal, Plancon, Sebastien, Margue, Christiane, Pradier, Olivier, Fondu, Pierre, Kieffer, Nelly, Springer, Timothy A, Deckmyn, Hans

“…Three heterozygous mutations were identified in the genes encoding platelet integrin receptor {alpha}IIbb3 in a patient with an ill defined platelet disorder:…”
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