Search Results - "Plamper, Mark L"

Influence of prior illness on exertional heat stroke presentation and outcome by King, Michelle A, Ward, Matthew D, Mayer, Thomas A, Plamper, Mark L, Madsen, Clifford M, Cheuvront, Samuel N, Kenefick, Robert W, Leon, Lisa R

“…Precipitating factors that contribute to the severity of exertional heat stroke (EHS) are unclear. The purpose of this study was to determine the effect of…”
Get full text

Amino acid solution mitigates hypothermia response and intestinal damage following exertional heat stroke in male mice by King, Michelle A., Grosche, Astrid, Ward, Shauna M., Ward, Jermaine A., Sasidharan, Anusree, Mayer, Thomas A., Plamper, Mark L., Xu, Xiaodong, Ward, Matthew D., Clanton, Thomas L., Vidyasagar, Sadasivan

“…Increased gut permeability is implicated in the initiation and extent of the cytokine inflammatory response associated with exertional heat stroke (EHS). The…”
Get full text

Retinoid uptake, processing, and secretion in human iPS-RPE support the visual cycle by Muñiz, Alberto, Greene, Whitney A, Plamper, Mark L, Choi, Jae Hyek, Johnson, Anthony J, Tsin, Andrew T, Wang, Heuy-Ching

“…Retinal pigmented epithelium derived from human induced pluripotent stem (iPS) cells (iPS-RPE) may be a source of cells for transplantation. For this reason,…”
Get full text

Passive Heating after Heat‐ and Exercise‐Induced Collapse in Mice Induces a Severe Exertional Heat Stroke Phenotype that More Accurately Recapitulates Human Cases by Henderson, Chloe G., Plamper, Mark L., Mayer, Thomas A., Ward, Jermaine A., Ward, Shauna M., Leon, Lisa R., Oki, Kentaro

“…Development of a mouse exertional heat stroke (EHS) model that more accurately recapitulates human EHS cases is essential in characterizing the pathophysiology…”
Get full text

Prior Vancomycin Treatment Mitigates Coagulation and Death in a Severe Exertional Heat Stroke Mouse ModelPrior Vancomycin treatment mitigates coagulation and death in a severe Exertional Heat Stroke mouse model by Ward, Jermaine A., Ward, Shauna M., Plamper, Mark L., Henderson, Chloe G., Mayer, Thomas A., Leon, Lisa R., Oki, Kentaro

“…During exercise, intestinal leakage of lipopolysaccharide (LPS or endotoxin: a component in the cell walls of Gram‐negative bacteria) into circulation is…”
Get full text

Vancomycin modestly attenuates symptom severity during onset of and recovery from exertional heat stroke in mice by Oki, Kentaro, Ward, Jermaine A, Ward, Shauna M, Plamper, Mark L, Henderson, Chloe G, Mayer, Thomas A, Caldwell, Aaron R, Leon, Lisa R

“…Increased intestinal permeability during exertion and subsequent leakage of bacteria into circulation is hypothesized to accelerate exertional heat stroke…”
Get full text

Identification of therapeutic targets in a murine model of severe exertional heat stroke by Oki, Kentaro, Henderson, Chloe G, Ward, Shauna M, Ward, Jermaine A, Plamper, Mark L, Mayer, Thomas A, Caldwell, Aaron R, Leon, Lisa R

“…Exertional heat stroke (EHS) is a potentially lethal condition resulting from high core body temperatures (T ) in combination with a systemic inflammatory…”
Get more information

Impact of successive exertional heat injuries on thermoregulatory and systemic inflammatory responses in mice by Caldwell, Aaron R, Oki, Kentaro, Ward, Shauna M, Ward, Jermaine A, Mayer, Thomas A, Plamper, Mark L, King, Michelle A, Leon, Lisa R

“…The purpose of the study was to determine if repeated exertional heat injuries (EHIs) worsen the inflammatory response. We assessed the impact of a single EHI…”
Get full text

Pretreatment with indomethacin results in increased heat stroke severity during recovery in a rodent model of heat stroke by Audet, Gerald N, Dineen, Shauna M, Stewart, Delisha A, Plamper, Mark L, Pathmasiri, Wimal W, McRitchie, Susan L, Sumner, Susan J, Leon, Lisa R

“…It has been suggested that medications can increase heat stroke (HS) susceptibility/severity. We investigated whether the nonsteroidal anti-inflammatory drug…”
Get full text

Pathophysiology of blast-induced ocular trauma with apoptosis in the retina and optic nerve by Wang, Heuy-Ching Hetty, Choi, Jae-Hyek, Greene, Whitney A, Plamper, Mark L, Cortez, Hector E, Chavko, Mikulas, Li, Yansong, Dalle Lucca, Jurandir J, Johnson, Anthony J

“…Blast-induced ocular trauma is a frequent cause of morbidity for survivors of improvised explosive devices. Blast overpressure (BOP) of 120 ± 7 KPa has been…”
Get full text

MicroRNA expression profiles of human iPS cells, retinal pigment epithelium derived from iPS, and fetal retinal pigment epithelium by Greene, Whitney A, Muñiz, Alberto, Plamper, Mark L, Kaini, Ramesh R, Wang, Heuy-Ching

“…The objective of this report is to describe the protocols for comparing the microRNA (miRNA) profiles of human induced-pluripotent stem (iPS) cells, retinal…”
Get full text

Identifying Latent Factors Related To Mild And Severe Heat Injury In Mice: 2918 by Caldwell, Aaron R., Henderson, Chloe G., Plamper, Mark L., Ward, Shauna M., Ward, Jermaine A., Mayer, Thomas A., Leon, Lisa R., Oki, Kentaro

Get full text

An Increase in Thermotolerance Is Associated with Elevated Levels of Heat Shock Protein 70 (HSP70) in a Mouse Exertional Heat Stroke Model by Dineen, Shauna M., Ward, Jermaine A., Plamper, Mark L., Mayer, Thomas A., Leon, Lisa R.

“…Abstract only Recent data from our laboratory showedthat one exertional heat stroke (EHS) exposure improved thermal tolerance inmice who were exposed to the…”
Get full text

Prior Viral Illness Exacerbates the Severity of Lung Injury in a Mice Heat Stroke Model by Plamper, Mark l., Dineen, Shauna M., King, Michelle A., Leon, Lisa R.

“…Heat Stroke (HS) is a common threatto both civilian and warfighter populations, however the mechanisms underlying tissueinjury are unknown. Acute respiratory…”
Get full text

Prior Infection and Resultant Coagulopathy Increase Heat Stroke Severity by Dineen, Shauna Marie, Plamper, Mark L., Ward, Jermaine A., Audet, Gerald N, Leon, Lisa R

“…Abstract only Anecdotally, it has been suggested that prior viral infection increases heat stroke (HS) susceptibility and severity. HS and systemic infection…”
Get full text

Monocyte chemoattractant protein‐1 expression in the lung and kidney is a marker of severity during heat stroke recovery in rats by Plamper, Mark L, Ward, Jermaine A, Leon, Lisa R, Audet, Gerald N

“…Abstract only Heat Stroke (HS) is a common environmental threat to both civilian and war fighter populations. Building on previous studies, our aim is to…”
Get full text

MicroRNA Expression Profiles of Human iPS Cells, Retinal Pigment Epithelium Derived From iPS, and Fetal Retinal Pigment Epithelium by Greene, Whitney A., Muñiz, Alberto, Plamper, Mark L., Kaini, Ramesh R., Wang, Heuy-Ching

Get full text