Search Results - "Plakhova, Vera B."

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    Arginine-Containing Tripeptides as Analgesic Substances: The Possible Mechanism of Ligand-Receptor Binding to the Slow Sodium Channel by Rogachevskii, Ilya V, Plakhova, Vera B, Penniyaynen, Valentina A, Kalinina, Arina D, Podzorova, Svetlana A, Samosvat, Dmitriy M, Zegrya, Georgy G, Krylov, Boris V

    “…Two short arginine-containing tripeptides, H-Arg-Arg-Arg-OH (TP1) and Ac-Arg-Arg-Arg-NH (TP2), have been shown by the patch-clamp method to modulate the Na 1.8…”
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    Journal Article
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    Role of the Rhamnosyl Residue of Ouabain in the Activation of the Na,K-ATPase Signaling Function by Rogachevskii, Ilya V, Samosvat, Dmitriy M, Penniyaynen, Valentina A, Plakhova, Vera B, Podzorova, Svetlana A, Ma, Ke, Zegrya, Georgy G, Krylov, Boris V

    Published in Life (Basel, Switzerland) (01-07-2023)
    “…The signaling or non-pumping Na,K-ATPase function was first observed by us in the nociceptive neuron; Na,K-ATPase transduced the signals from the opioid-like…”
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    Mechanism of pain relief by low-power infrared irradiation: ATP is an IR-target molecule in nociceptive neurons by Yachnev, Igor L, Plakhova, Vera B, Podzorova, Svetlana A, Shelykh, Tatiana N, Rogachevsky, Ilya V, Krylov, Boris V

    “…Effects of infrared (IR) radiation generated by a low-power CO2-laser on the membrane of cultured dissociated nociceptive neurons of newborn rat spinal ganglia…”
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    New approaches to the design of analgesic medicinal substances by Rogachevskii, Ilia V, Plakhova, Vera B, Penniyaynen, Valentina A, Terekhin, Stanislav G, Podzorova, Svetlana A, Krylov, Boris V

    “…A gamma-pyrone derivative, comenic acid, activates the opioid-like receptor-mediated signaling pathway that modulates the Na 1.8 channels in the primary…”
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    Molecular mechanisms and signaling by comenic acid in nociceptive neurons influence the pathophysiology of neuropathic pain by Penniyaynen, Valentina A., Plakhova, Vera B., Rogachevskii, Ilya V., Terekhin, Stanislav G., Podzorova, Svetlana A., Krylov, Boris V.

    Published in Pathophysiology (Amsterdam) (01-09-2019)
    “…Comenic acid (CA), a specific agonist of opioid-like receptors, effectively and safely relieves neuropathic pain by decreasing the NaV1.8 channel voltage…”
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