Search Results - "Placzek, Ekaterina A."
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RNA interference-mediated knockdown of dynamin 2 reduces endocannabinoid uptake into neuronal dCAD cells
Published in Molecular pharmacology (01-07-2008)“…The precise mechanism by which the cellular uptake of the endocannabinoid anandamide (AEA) occurs has been the source of much debate. In the current study, we…”
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2
Mechanisms for recycling and biosynthesis of endogenous cannabinoids anandamide and 2-arachidonylglycerol
Published in Journal of neurochemistry (01-11-2008)“…The mechanisms of endogenous cannabinoid biosynthesis are not completely understood. We hypothesized that anandamide could be recycled by the cell to form new…”
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3
Membrane microdomains and metabolic pathways that define anandamide and 2-arachidonyl glycerol biosynthesis and breakdown
Published in Neuropharmacology (01-12-2008)“…Anandamide (AEA) and 2-arachidonyl glycerol (2-AG), endogenous ligands for the CB1 and CB2 cannabinoid receptors, are referred to as endocannabinoids because…”
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4
A peptide biosensor for detecting intracellular Abl kinase activity using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
Published in Analytical biochemistry (01-02-2010)“…Many cancers are characterized by changes in protein phosphorylation as a result of kinase dysregulation. Disruption of Abl kinase signaling through the…”
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5
Lipidomic metabolism analysis of the endogenous cannabinoid anandamide (N-arachidonylethanolamide)
Published in Journal of pharmaceutical and biomedical analysis (02-11-2010)“…Elucidation of pathways involved with lipid metabolism has been limited by analytical challenges associated with detection and structure identification. A…”
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6
Contributions of extracellular and intracellular calcium in the biosynthesis of endocannabinoids
Published in The FASEB journal (01-03-2008)“…Abstract only The actions of a plant‐derived cannabinoid delta 9 ‐tetrahydrocannabinol (δ 9 ‐THC) are mimicked by the endogenous cannabinoids anandamide (AEA)…”
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7
A peptide biosensor for detecting intracellular Abl kinase activity using MALDI-TOF MS
Published in Analytical biochemistry (07-10-2009)“…Many cancers are characterized by changes in protein phosphorylation as a result of kinase dysregulation. Disruption of Abl kinase signaling through the…”
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Journal Article -
8
Toward a molecular and bioanalytical understanding of endogenous cannabinoid recycling and biosynthesis
Published 01-01-2008“…The endocannabinoids anandamide and 2-arachidonyl glycerol mimic the actions of Δ9-tetrahydrocannabinol, the active ingredient in marijuana. Recently the…”
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Dissertation