Search Results - "Place, R. F."

miR-449a targets HDAC-1 and induces growth arrest in prostate cancer by Noonan, E J, Place, R F, Pookot, D, Basak, S, Whitson, J M, Hirata, H, Giardina, C, Dahiya, R

“…Histone deacetylases (HDACs) are frequently overexpressed in broad range of cancer types, where they alter cellular epigenetic programming to promote cell…”
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Retraction Note: Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity by Kikuno, N., Shiina, H., Urakami, S., Kawamoto, K., Hirata, H., Tanaka, Y., Place, R. F., Pookot, D., Majid, S., Igawa, M., Dahiya, R.

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Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity by KIKUNO, N, SHIINA, H, DAHIYA, R, URAKAMI, S, KAWAMOTO, K, HIRATA, H, TANAKA, Y, PLACE, R. F, POOKOT, D, MAJID, S, IGAWA, M

“…Astrocyte-elevated gene-1 (AEG-1) has been reported to be upregulated in several malignancies and play a critical role in Ha-ras-mediated oncogenesis through…”
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Future Prospects for the Treatment of Graves' Hyperthyroidism and Eye Disease by Neumann, S, Place, R F, Krieger, C C, Gershengorn, M C

“…Although there are adequate therapies for Graves' hyperthyroidism, mild to moderate Graves' orbitopathy (GO) is usually treated symptomatically whereas…”
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RETRACTED ARTICLE: Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity by Kikuno, N, Shiina, H, Urakami, S, Kawamoto, K, Hirata, H, Tanaka, Y, Place, R F, Pookot, D, Majid, S, Igawa, M, Dahiya, R

“…Astrocyte-elevated gene-1 (AEG-1) has been reported to be upregulated in several malignancies and play a critical role in Ha-ras-mediated oncogenesis through…”
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Cytokine-Induced Stabilization of Newly Synthesized IκB-α by Place, Robert F., Haspeslagh, Derek, Hubbard, Andrea K., Giardina, Charles

“…NF-κB activation is triggered by the degradation of inhibitory proteins, such as IκB-α. IκB-α levels are only transiently lowered since one gene activated by…”
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Hsp70B′ regulation and function by Noonan, Emily J., Place, Robert F., Giardina, Charles, Hightower, Lawrence E.

“…Heat shock protein (Hsp) 70B′ is a human Hsp70 chaperone that is strictly inducible, having little or no basal expression levels in most cells. Using siRNAs to…”
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HDAC inhibition prevents NF-κB activation by suppressing proteasome activity: Down-regulation of proteasome subunit expression stabilizes IκBα by Place, Robert F., Noonan, Emily J., Giardina, Charles

“…The short chain fatty acid (SCFA) butyrate (BA) and other histone deacetylase (HDAC) inhibitors can rapidly induce cell cycle arrest and differentation of…”
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Cytokine-induced stabilization of newly synthesized I(kappa)B-alpha by Place, R F, Haspeslagh, D, Hubbard, A K, Giardina, C

“…NF-kappaB activation is triggered by the degradation of inhibitory proteins, such as I(kappa)B-alpha. I(kappa)B-alpha levels are only transiently lowered since…”
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Induced stabilization of IκBα can facilitate its re-synthesis and prevent sequential degradation by Place, Robert F., Haspeslagh, Derek, Giardina, Charles

“…The transcription factor NF‐κB is responsible for regulating genes that can profoundly impact cell proliferation, apoptosis, inflammation, and immune…”
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HDACs and the senescent phenotype of WI-38 cells by Place, Robert F, Noonan, Emily J, Giardina, Charles

“…Normal cells possess a limited proliferative life span after which they enter a state of irreversible growth arrest. This process, known as replicative…”
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