Search Results - "Pla Parada, Indira"
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Mapping the Melanoma Plasma Proteome (MPP) Using Single-Shot Proteomics Interfaced with the WiMT Database
Published in Cancers (10-12-2021)“…Plasma analysis by mass spectrometry-based proteomics remains a challenge due to its large dynamic range of 10 orders in magnitude. We created a methodology…”
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Novel protein markers of androgen activity in humans: proteomic study of plasma from young chemically castrated men
Published in eLife (01-03-2022)“…Reliable biomarkers of androgen activity in humans are lacking. The aim of this study was, therefore, to identify new protein markers of biological androgen…”
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Quantitative Assessment of Urea In-Solution Lys-C/Trypsin Digestions Reveals Superior Performance at Room Temperature over Traditional Proteolysis at 37 °C
Published in Journal of proteome research (06-07-2018)“…Urea-containing buffer solutions are generally used in proteomic studies to aid protein denaturation and solubilization during cell and tissue lysis. It is…”
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Predicting immune checkpoint therapy response in three independent metastatic melanoma cohorts
Published in Frontiers in oncology (02-07-2024)“…While Immune checkpoint inhibition (ICI) therapy shows significant efficacy in metastatic melanoma, only about 50% respond, lacking reliable predictive…”
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Mitochondrial dysfunction and immune suppression in BRAF V600E‐mutated metastatic melanoma
Published in Clinical and translational medicine (01-07-2024)“…Melanoma, characterized by its aggressive behaviour and high metastatic capacity, faces further challenges with the BRAF V600E mutation, which significantly…”
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The human melanoma proteome atlas—Defining the molecular pathology
Published in Clinical and translational medicine (01-07-2021)“…The MM500 study is an initiative to map the protein levels in malignant melanoma tumor samples, focused on in‐depth histopathology coupled to proteome…”
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