Search Results - "Plácido, Ana I."

Arbutus unedo L.: From traditional medicine to potential uses in modern pharmacotherapy by Morgado, Sandra, Morgado, Manuel, Plácido, Ana I., Roque, Fátima, Duarte, Ana Paula

“…Arbutus unedo L., the strawberry tree (Ericaceae family) is of increasing interest because of its common traditional, industrial, chemical and pharmaceutical…”
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Effectiveness of Interventions to Reduce Potentially Inappropriate Medication in Older Patients: A Systematic Review by Rodrigues, Daniela A, Plácido, Ana I, Mateos-Campos, Ramona, Figueiras, Adolfo, Herdeiro, Maria Teresa, Roque, Fátima

“…Age-related multiple comorbidities cause older adults to be prone to the use of potentially inappropriate medicines (PIM) resulting in an increased risk of…”
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Phosphatase 2A Inhibition Affects Endoplasmic Reticulum and Mitochondria Homeostasis Via Cytoskeletal Alterations in Brain Endothelial Cells by Plácido, Ana I., Pereira, Cláudia M. F., Correira, Sónia C., Carvalho, Cristina, Oliveira, Catarina R., Moreira, Paula I.

“…The loss of endothelial cells (ECs) homeostasis is a trigger for cerebrovascular dysfunction that is a common event in several neurodegenerative disorders such…”
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Usability of APIMedOlder: A Web Application to Manage Potentially Inappropriate Medication in Older Adults by A Rodrigues, Daniela, I Plácido, Ana, Mateos-Campos, Ramona, Figueiras, Adolfo, Herdeiro, Maria Teresa, Roque, Fátima

“…Considering the increase in the proportion of the older population worldwide, the demand for health system resources also arises. These tools optimize clinical…”
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Prescription of Potentially Inappropriate Medication in Older Inpatients of an Internal Medicine Ward: Concordance and Overlap Among the EU(7)-PIM List and Beers and STOPP Criteria by Perpétuo, Carla, Plácido, Ana I., Rodrigues, Daniela, Aperta, Jorge, Piñeiro-Lamas, Maria, Figueiras, Adolfo, Herdeiro, Maria Teresa, Roque, Fátima

“…Background: Age-related comorbidities prone older adults to polypharmacy and to an increased risk of potentially inappropriate medication (PIM) use. This work…”
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Clinical pharmacists´ interventions in the management of type 2 diabetes mellitus: a systematic review by Pousinho, Sarah, Morgado, Manuel, Plácido, Ana I., Roque, Fátima, Falcão, Amílcar, Alves, Gilberto

“…Background: Type 2 diabetes mellitus is a chronic disease that is reaching epidemic proportions worldwide. It is imperative to adopt an integrated strategy,…”
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Potentially Inappropriate Medication Prescribing in Older Adults According to EU(7)-Potentially Inappropriate Medication List: A Nationwide Study in Portugal by Rodrigues, Daniela A., Plácido, Ana I., Tavares, Ana Bárbara, Azevedo, Daniela, Mateos-Campos, Ramona, Figueiras, Adolfo, Herdeiro, Maria Teresa, Roque, Fátima

“…Portugal has among the highest rates of dependency among older adults in Europe. Older adults with aging-related comorbidities are prone to the use of…”
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Perspectives on mitochondrial uncoupling proteins-mediated neuroprotection by Cardoso, Susana, Correia, Sónia, Carvalho, Cristina, Candeias, Emanuel, Plácido, Ana I., Duarte, Ana I., Seiça, Raquel M., Moreira, Paula I.

“…The integrity of mitochondrial function is essential to cell life. It follows that disturbances of mitochondrial function will lead to disruption of cell…”
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The role of mitochondrial disturbances in Alzheimer, Parkinson and Huntington diseases by Carvalho, Cristina, Correia, Sónia C, Cardoso, Susana, Plácido, Ana I, Candeias, Emanuel, Duarte, Ana I, Moreira, Paula I

“…Mitochondria are highly dynamic organelles involved in a multitude of cellular events. Disturbances of mitochondrial function and dynamics are associated with…”
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Enhanced Amyloidogenic Processing of Amyloid Precursor Protein and Cell Death Under Prolonged Endoplasmic Reticulum Stress in Brain Endothelial Cells by Plácido, Ana I., Oliveira, Catarina R., Moreira, Paula I., Pereira, Cláudia Maria F.

“…Cerebral amyloid angiopathy resulting from the deposition of misfolded amyloid beta (Aβ) peptide in the walls of brain’s blood vessels is exhibited by the…”
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The impairment of insulin signaling in Alzheimer's disease by Candeias, Emanuel, Duarte, Ana I., Carvalho, Cristina, Correia, Sónia C., Cardoso, Susana, Santos, Renato X., Plácido, Ana I., Perry, George, Moreira, Paula I.

“…Alterations of the insulin signaling cascade underlie cognitive decline and the development of several neurodegenerative diseases. In recent years, a great…”
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Early Real-World Data to Assess Benefits and Risks of COVID-19 Vaccines: A Systematic Review of Methods by Ribeiro, Tatiane B, Roque, Fátima, Ida, Fidelia, Plácido, Ana I, Vu, Mai, Hernández-Muñoz, Jose J, Herdeiro, Maria Teresa

“…Since the authorization of the first COVID-19 vaccines in December 2020, multiple studies using real-world data (RWD) have been published to assess their…”
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Modulation of endoplasmic reticulum stress: an opportunity to prevent neurodegeneration? by Placido, Ana I, Pereira, Claudia M F, Duarte, Ana I, Candeias, Emanuel, Correia, Sonia C, Carvalho, Cristina, Cardoso, Susana, Oliveira, Catarina R, Moreira, Paula I

“…Neurodegenerative diseases (e.g. Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis and prion-related diseases) have…”
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Profile of Prescription Medication in an Internal Medicine Ward by Perpétuo, Carla, Plácido, Ana I, Aperta, Jorge, Herdeiro, Maria Teresa, Roque, Fátima

“…Aging-related loss of resilience associated with the lack of evidence regarding the therapeutic efficacy of medicines can prompt a lack of efficacy of…”
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Alzheimer disease as a vascular disorder: Where do mitochondria fit? by Correia, Sónia C., Santos, Renato X., Cardoso, Susana, Carvalho, Cristina, Candeias, Emanuel, Duarte, Ana I., Plácido, Ana I., Santos, Maria S., Moreira, Paula I.

“…Although the precise culprit in the etiopathogenesis of Alzheimer disease (AD) is still obscure, defective mitochondria functioning has been proposed to be an…”
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Drug-related Problems in Home-dwelling Older Adults: A Systematic Review by Plácido, Ana I., Herdeiro, Maria Teresa, Morgado, Manuel, Figueiras, Adolfo, Roque, Fátima

“…The complex combination of medicines associated with age-related physiological alterations leads older adults to experience drug-related problems (DRPs). The…”
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Potentially Inappropriate Medication at Admission and at Discharge: A Geriatric Study in an Internal Medicine Service in Portugal by Perpétuo, Carla, Plácido, Ana I, Aperta, Jorge, Figueiras, Adolfo, Herdeiro, Maria Teresa, Roque, Fátima

“…Aging is associated with an increase in the prevalence of chronic diseases and polypharmacy, and with the prescription of potentially inappropriate medications…”
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Defective HIF signaling pathway and brain response to hypoxia in neurodegenerative diseases: not an "iffy" question by Correia, Sónia C, Carvalho, Cristina, Cardoso, Susana, Santos, Renato X, Plácido, Ana I, Candeias, Emanuel, Duarte, Ana I, Moreira, Paula I

“…Brain structural and functional integrity exquisitely relies on a regular supply of oxygen. In order to circumvent the potential deleterious consequences of…”
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Critical Analysis of Immune Checkpoint Inhibitor Immunotoxicity Management by Lopes, Carolina, Morgado, Sandra, Plácido, Ana I., Roque, Fátima, Morgado, Manuel

“…Immune checkpoint inhibitors are a revolution in cancer treatment, having a better toxicity profile than chemotherapy. However, many mechanisms and management…”
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