Search Results - "Pizzol, Felipe Dal"
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Characterization and modulation of microglial phenotypes in an animal model of severe sepsis
Published in Journal of cellular and molecular medicine (01-01-2020)“…We aim to characterize the kinetics of early and late microglial phenotypes after systemic inflammation in an animal model of severe sepsis and the effects of…”
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Sepsis sensitizes behavioural amphetamine responses while inducing inflammatory and neurotrophic vulnerability in the cecal ligation and puncture model
Published in The European journal of neuroscience (01-03-2024)“…The present study aimed to evaluate if sepsis sensitizes behavioural and biochemical responses induced by m‐amphetamine. For this, Wistar rats were submitted…”
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Lithium ameliorates sleep deprivation‐induced mania‐like behavior, hypothalamic‐pituitary‐adrenal (HPA) axis alterations, oxidative stress and elevations of cytokine concentrations in the brain and serum of mice
Published in Bipolar disorders (01-06-2017)“…Objectives The goal of the present study was to investigate the effects of lithium administration on behavior, oxidative stress parameters and cytokine levels…”
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Author Correction: Enriched environment causes epigenetic changes in hippocampus and improves long-term cognitive function in sepsis
Published in Scientific reports (06-12-2022)Get full text
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Glasgow coma scale pupil score (GCS-P) and the hospital mortality in severe traumatic brain injury: analysis of 1,066 Brazilian patients
Published in Arquivos de neuro-psiquiatria (01-05-2023)“…Pupil reactivity and the Glasgow Coma Scale (GCS) score are the most clinically relevant information to predict the survival of traumatic brain injury (TBI)…”
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Intra-articular Treatment with Triamcinolone Hexacetonide Associated with Gold Nanoparticles Reduces Cartilage Degeneration in an Animal Model of Osteoarthritis
Published in Current drug targets (01-01-2023)“…The association between triamcinolone hexacetonide (TH) and gold nanoparticles (GNPs) represents a promising treatment due to the potential anti-inflammatory…”
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Antioxidant Treatment Reverses Organ Failure in Rat Model of Sepsis: Role of Antioxidant Enzymes Imbalance, Neutrophil Infiltration, and Oxidative Stress
Published in The Journal of surgical research (15-05-2011)“…Background Some of the postulated molecular mechanisms of sepsis progression are linked with the imbalance between reactive oxygen species (ROS) production and…”
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Biomarkers for sepsis: more than just fever and leukocytosis-a narrative review
Published in Critical care (London, England) (06-01-2022)“…A biomarker describes a measurable indicator of a patient's clinical condition that can be measured accurately and reproducibly. Biomarkers offer utility for…”
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Increased on oxidative brain injury in the diabetic rats following sepsis
Published in Synapse (New York, N.Y.) (01-09-2014)“…ABSTRACT Diabetes has been the subject of recent research by increase susceptibility to infections, thus the aim of this study was to evaluate in animal model…”
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Oxidative stress and inflammatory markers in normal pregnancy and preeclampsia
Published in The journal of obstetrics and gynaecology research (01-12-2008)“…Aim: Although previous investigators have demonstrated the presence of oxidative stress and inflammation in preeclampsia, none directly correlate both to…”
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Oxidative stress and metabolism in animal model of colitis induced by dextran sulfate sodium
Published in Journal of gastroenterology and hepatology (01-11-2007)“…Background and Aim: Ulcerative colitis is a chronic inflammatory disease of the gastrointestinal tract. Its etiology remains unclear, but it appears to result…”
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CFL1 expression levels as a prognostic and drug resistance marker in nonsmall cell lung cancer
Published in Cancer (01-08-2010)“…BACKGROUND: Nonsmall cell lung cancer (NSCLC) is the major determinant of overall cancer mortality worldwide. Despite progress in molecular research, current…”
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Plasma nitric oxide, endothelin-1, arginase and superoxide dismutase in pre-eclamptic women
Published in The journal of obstetrics and gynaecology research (01-12-2008)“…Aim: The aim of this study was to determine several parameters of nitric oxide metabolism in pre‐eclamptic patients. Methods: We conducted a nested…”
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Luteinizing Hormone and Testosterone Levels during Acute Phase of Severe Traumatic Brain Injury: Prognostic Implications for Adult Male Patients
Published in Frontiers in endocrinology (Lausanne) (13-02-2018)“…Traumatic brain injury (TBI) is a worldwide core public health problem affecting mostly young male subjects. An alarming increase in incidence has turned TBI…”
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Increased oxidative stress after repeated amphetamine exposure: possible relevance as a model of mania
Published in Bipolar disorders (01-06-2006)“…Background: Acute mania can be modeled in animals using D‐amphetamine (AMPH). Acute AMPH injections are associated with monoamine depletion, loss of…”
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Brain Barrier Breakdown as a Cause and Consequence of Neuroinflammation in Sepsis
Published in Molecular neurobiology (01-02-2018)“…The blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB) are important for the maintenance of brain homeostasis . During sepsis,…”
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Effects of omega-3 supplementation on interleukin and neurotrophin levels in an animal model of schizophrenia
Published in Anais da Academia Brasileira de Ciências (01-08-2015)“…New studies suggest that polyunsaturated fatty acids, such as omega-3, may reduce the symptoms of schizophrenia. The present study evaluated the preventive…”
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Attenuation of bleomycin-induced lung injury and oxidative stress by N -acetylcysteine plus deferoxamine
Published in Pulmonary pharmacology & therapeutics (01-01-2008)“…Abstract Reactive oxygen species (ROS) play an important role in the pathogenesis of pulmonary injury and antioxidant therapy may be useful with impaired…”
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Brain-heart interaction after acute ischemic stroke
Published in Critical care (London, England) (21-04-2020)“…Early detection of cardiovascular dysfunctions directly caused by acute ischemic stroke (AIS) has become paramount. Researchers now generally agree on the…”
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Oxidative stress and mitochondrial dysfunction contributes to postoperative cognitive dysfunction in elderly rats
Published in Brain, behavior, and immunity (01-10-2018)“…•Elderly people are highly susceptible to postoperative cognitive dysfunction.•Tibial fracture model was used to assess postoperative memory function in old…”
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