Search Results - "Pizio, Antonella Di"
-
1
Comparative functional analysis reveals differential nucleotide sensitivity between human and mouse UCP1
Published in Acta Physiologica (01-09-2024)“…Aim Mitochondrial uncoupling protein 1 (UCP1) is a unique protein of brown adipose tissue. Upon activation by free fatty acids, UCP1 facilitates a thermogenic…”
Get full text
Journal Article -
2
Coronaviruses and the Chemical Senses: Past, Present, and Future
Published in Chemical senses (07-07-2020)“…Abstract A wealth of rapidly evolving reports suggests that olfaction and taste disturbances may be manifestations of the novel COVID-19 pandemic. While…”
Get full text
Journal Article -
3
Assessing the extent and timing of chemosensory impairments during COVID-19 pandemic
Published in Scientific reports (01-09-2021)“…Chemosensory impairments have been established as a specific indicator of COVID-19. They affect most patients and may persist long past the resolution of…”
Get full text
Journal Article -
4
Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration
Published in Nature communications (11-08-2021)“…Pathogens are thought to use host molecular cues to control when to initiate life-cycle transitions, but these signals are mostly unknown, particularly for the…”
Get full text
Journal Article -
5
Computational Studies of Smell and Taste Receptors
Published in Israel journal of chemistry (01-08-2014)“…Smell and taste are among the basic senses with which we perceive the world around us. In addition to enabling recognition of chemical moieties that provide…”
Get full text
Journal Article -
6
Recombinant Ostreolysin Induces Brown Fat‐Like Phenotype in HIB‐1B Cells
Published in Molecular nutrition & food research (01-03-2019)Get full text
Journal Article -
7
Phylogenetic and Mutation Analysis of the Venezuelan Equine Encephalitis Virus Sequence Isolated in Costa Rica from a Mare with Encephalitis
Published in Veterinary sciences (28-05-2022)“…Venezuelan Equine Encephalitis virus (VEEV) is an arboviral pathogen in tropical America that causes lethal encephalitis in horses and humans. VEEV is…”
Get full text
Journal Article -
8
BitterDB: taste ligands and receptors database in 2019
Published in Nucleic acids research (08-01-2019)“…Abstract BitterDB (http://bitterdb.agri.huji.ac.il) was introduced in 2012 as a central resource for information on bitter-tasting molecules and their…”
Get full text
Journal Article -
9
Activation Profile of TAS2R2, the 26th Human Bitter Taste Receptor
Published in Molecular nutrition & food research (01-06-2023)“…Scope To avoid ingestion of potentially harmful substances, humans are equipped with about 25 bitter taste receptor genes (TAS2R) expressed in oral taste…”
Get full text
Journal Article -
10
The key food odorant receptive range of broadly tuned receptor OR2W1
Published in Food chemistry (01-05-2022)“…•OR2W1 is the most broadly tuned human odorant receptor known.•Two-thirds of its now 153 chemically diverse, known agonists are key food odorants.•Evolutionary…”
Get full text
Journal Article -
11
Beyond the Flavour: The Potential Druggability of Chemosensory G Protein-Coupled Receptors
Published in International journal of molecular sciences (20-03-2019)“…G protein-coupled receptors (GPCRs) belong to the largest class of drug targets. Approximately half of the members of the human GPCR superfamily are…”
Get full text
Journal Article -
12
In Silico Molecular Study of Tryptophan Bitterness
Published in Molecules (Basel, Switzerland) (11-10-2020)“…Tryptophan is an essential amino acid, required for the production of serotonin. It is the most bitter amino acid and its bitterness was found to be mediated…”
Get full text
Journal Article -
13
COVID-19 and the Chemical Senses: Supporting Players Take Center Stage
Published in Neuron (Cambridge, Mass.) (22-07-2020)“…The main neurological manifestation of COVID-19 is loss of smell or taste. The high incidence of smell loss without significant rhinorrhea or nasal congestion…”
Get full text
Journal Article -
14
Chemoinformatics View on Bitter Taste Receptor Agonists in Food
Published in Journal of agricultural and food chemistry (24-11-2021)“…Food compounds with a bitter taste have a role in human health, both for their capability to influence food choice and preferences and for their possible…”
Get full text
Journal Article -
15
Allostery in Its Many Disguises: From Theory to Applications
Published in Structure (London) (02-04-2019)“…Allosteric regulation plays an important role in many biological processes, such as signal transduction, transcriptional regulation, and metabolism. Allostery…”
Get full text
Journal Article -
16
Bitter and sweet tasting molecules: It's complicated
Published in Neuroscience letters (01-05-2019)“…[Display omitted] •Bitter and sweet compounds are numerous and structurally diverse.•The majority of bitter compounds have higher hydrophobicity and more…”
Get full text
Journal Article -
17
Rational design of agonists for bitter taste receptor TAS2R14: from modeling to bench and back
Published in Cellular and molecular life sciences : CMLS (01-02-2020)“…Human bitter taste receptors (TAS2Rs) are a subfamily of 25 G protein-coupled receptors that mediate bitter taste perception. TAS2R14 is the most broadly tuned…”
Get full text
Journal Article -
18
Astringent Gallic Acid in Red Wine Regulates Mechanisms of Gastric Acid Secretion via Activation of Bitter Taste Sensing Receptor TAS2R4
Published in Journal of agricultural and food chemistry (15-09-2021)“…Red wine is rich in phenolic compounds, which chiefly determine its characteristic taste. One of its major phenolic acid constituents for which an astringency,…”
Get full text
Journal Article -
19
Editorial: Peptide-binding GPCRs coming of age
Published in Frontiers in endocrinology (Lausanne) (21-04-2023)Get full text
Journal Article -
20
Machine Learning Predictor for Bitter Peptides
Published in Lebensmittelchemie (01-09-2024)Get full text
Journal Article