Search Results - "Pizard, Anne"

Beneficial Impact of Eicosapentaenoic Acid on the Adverse Effects Induced by Palmitate and Hyperglycemia on Healthy Rat Chondrocyte by Deng, Chaohua, Presle, Nathalie, Pizard, Anne, Guillaume, Cécile, Bianchi, Arnaud, Kempf, Hervé

“…Osteoarthritis (OA) is the most prevalent form of arthritis and a major cause of pain and disability. The pathology of OA involves the whole joint in an…”
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Smooth Muscle Cell Mineralocorticoid Receptors Are Mandatory for Aldosterone–Salt to Induce Vascular Stiffness by Galmiche, Guillaume, Pizard, Anne, Gueret, Alexandre, El Moghrabi, Soumaya, Ouvrard-Pascaud, Antoine, Berger, Stefan, Challande, Pascal, Jaffe, Iris Z., Labat, Carlos, Lacolley, Patrick, Jaisser, Frédéric

“…Arterial stiffness is recognized as a risk factor for many cardiovascular diseases. Aldosterone via its binding to and activation of the mineralocorticoid…”
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Cohort Profile: Rationale and design of the fourth visit of the STANISLAS cohort: a familial longitudinal population-based cohort from the Nancy region of France by Ferreira, João Pedro, Girerd, Nicolas, Bozec, Erwan, Mercklé, Ludovic, Pizard, Anne, Bouali, Sanae, Eby, Elise, Leroy, Céline, Machu, Jean-Loup, Boivin, Jean-Marc, Lamiral, Zohra, Rossignol, Patrick, Zannad, Faiez

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The Multifaceted Role of the Lysosomal Protease Cathepsins in Kidney Disease by Cocchiaro, Pasquale, De Pasquale, Valeria, Della Morte, Rossella, Tafuri, Simona, Avallone, Luigi, Pizard, Anne, Moles, Anna, Pavone, Luigi Michele

“…Kidney disease is worldwide the 12th leading cause of death affecting 8-16% of the entire population. Kidney disease encompasses acute (short-lasting episode)…”
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Plasma protein biomarkers and their association with mutually exclusive cardiovascular phenotypes: the FIBRO-TARGETS case–control analyses by Ferreira, João Pedro, Pizard, Anne, Machu, Jean-Loup, Bresso, Emmanuel, Rocca, Hans-Peter Brunner-La, Girerd, Nicolas, Leroy, Céline, González, Arantxa, Diez, Javier, Heymans, Stephane, Devignes, Marie-Dominique, Rossignol, Patrick, Zannad, Faiez

“…Background Hypertension, obesity and diabetes are major and potentially modifiable “risk factors” for cardiovascular diseases. Identification of biomarkers…”
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Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease by Wolf, Cordula M, Wang, Libin, Alcalai, Ronny, Pizard, Anne, Burgon, Patrick G, Ahmad, Ferhaan, Sherwood, Megan, Branco, Dorothy M, Wakimoto, Hiroko, Fishman, Glenn I, See, Vincent, Stewart, Colin L, Conner, David A, Berul, Charles I, Seidman, Christine E, Seidman, J.G

“…Abstract Mutations in the lamin A/C ( LMNA ) gene, which encodes nuclear membrane proteins, cause a variety of human conditions including dilated…”
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The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system by Moskowitz, Ivan P G, Pizard, Anne, Patel, Vickas V, Bruneau, Benoit G, Kim, Jae B, Kupershmidt, Sabina, Roden, Dan, Berul, Charles I, Seidman, Christine E, Seidman, Jonathan G

“…We report a critical role for the T-box transcription factor Tbx5 in development and maturation of the cardiac conduction system. We find that Tbx5 is…”
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Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss by Seidman, Christine E, Schönberger, Jost, Wang, Libin, Shin, Jordan T, Kim, Sang Do, Depreux, Frederic F S, Zhu, Hao, Zon, Leonard, Pizard, Anne, Kim, Jae B, MacRae, Calum A, Mungall, Andy J, Seidman, J G

“…We identified a human mutation that causes dilated cardiomyopathy and heart failure preceded by sensorineural hearing loss (SNHL). Unlike previously described…”
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Simultaneous characterization of metabolic, cardiac, vascular and renal phenotypes of lean and obese SHHF rats by Youcef, Gina, Olivier, Arnaud, L'Huillier, Clément P J, Labat, Carlos, Fay, Renaud, Tabcheh, Lina, Toupance, Simon, Rodriguez-Guéant, Rosa-Maria, Bergerot, Damien, Jaisser, Frédéric, Lacolley, Patrick, Zannad, Faiez, Laurent Vallar, Pizard, Anne

“…Individuals with metabolic syndrome (MetS) are prone to develop heart failure (HF). However, the deleterious effects of MetS on the continuum of events leading…”
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Tissue kallikrein is involved in the cardioprotective effect of AT1-receptor blockade in acute myocardial ischemia by Messadi-Laribi, Erij, Griol-Charhbili, Violaine, Pizard, Anne, Vincent, Marie-Pascale, Heudes, Didier, Meneton, Pierre, Alhenc-Gelas, François, Richer, Christine

“…Angiotensin-converting enzyme inhibitors limit infarct size in animal models of myocardial ischemia reperfusion injury. This effect has been shown to be due to…”
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In need of signalling pathway data by Pizard, Anne

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Genetic deficiency in tissue kallikrein activity in mouse and man: effect on arteries, heart and kidney by Pizard, Anne, Richer, Christine, Bouby, Nadine, Picard, Nicolas, Meneton, Pierre, Azizi, Michel, Alhenc-Gelas, François

“…Tissue kallikrein (KLK1) is a kinin-forming serine protease synthesized in many organs including arteries and kidney. Study of the physiological role of KLK1…”
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Determination of Bradykinin B2 Receptor in Vivo Phosphorylation Sites and Their Role in Receptor Function by Blaukat, Andree, Pizard, Anne, Breit, Andreas, Wernstedt, Christer, Alhenc-Gelas, François, Müller-Esterl, Werner, Dikic, Ivan

“…Reversible phosphorylation plays important roles in G protein-coupled receptor signaling, desensitization, and endocytosis, yet the precise location and role…”
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Connexin 40, a Target of Transcription Factor Tbx5, Patterns Wrist, Digits, and Sternum by Pizard, Anne, Burgon, Patrick G., Paul, David L., Bruneau, Benoit G., Seidman, Christine E., Seidman, J. G.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A Novel Protein-Protein Interaction between a G Protein-coupled Receptor and the Phosphatase SHP-2 Is Involved in Bradykinin-induced Inhibition of Cell Proliferation by Duchene, Johan, Schanstra, Joost P, Pecher, Christiane, Pizard, Anne, Susini, Christiane, Esteve, Jean-Pierre, Bascands, Jean-Loup, Girolami, Jean-Pierre

“…Mitogenic G protein-coupled receptor (GPCR) signaling has been extensively studied. In contrast, little is known about anti-mitogenic GPCR signaling. We show…”
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Myocardial fibrosis: biomedical research from bench to bedside by Gyöngyösi, Mariann, Winkler, Johannes, Ramos, Isbaal, Do, Quoc‐Tuan, Firat, Hüseyin, McDonald, Kenneth, González, Arantxa, Thum, Thomas, Díez, Javier, Jaisser, Frédéric, Pizard, Anne, Zannad, Faiez

“…Myocardial fibrosis refers to a variety of quantitative and qualitative changes in the interstitial myocardial collagen network that occur in response to…”
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The effect of spironolactone on cardiovascular function and markers of fibrosis in people at increased risk of developing heart failure: the heart ‘OMics’ in AGEing (HOMAGE) randomized clinical trial by Cleland, John G F, Ferreira, João Pedro, Mariottoni, Beatrice, Pellicori, Pierpaolo, Cuthbert, Joe, Verdonschot, Job A J, Petutschnigg, Johannes, Ahmed, Fozia Z, Cosmi, Franco, Brunner La Rocca, Hans-Peter, Mamas, Mamas A, Clark, Andrew L, Edelmann, Frank, Pieske, Burkert, Khan, Javed, McDonald, Ken, Rouet, Philippe, Staessen, Jan A, Mujaj, Blerim, González, Arantxa, Diez, Javier, Hazebroek, Mark, Heymans, Stephane, Latini, Roberto, Grojean, Stéphanie, Pizard, Anne, Girerd, Nicolas, Rossignol, Patrick, Collier, Tim J, Zannad, Faiez

“…Abstract Aims  To investigate the effects of spironolactone on fibrosis and cardiac function in people at increased risk of developing heart failure. Methods…”
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Searching for new mechanisms of myocardial fibrosis with diagnostic and/or therapeutic potential by Heymans, Stephane, González, Arantxa, Pizard, Anne, Papageorgiou, Anna P., López-Andrés, Natalia, Jaisser, Frédéric, Thum, Thomas, Zannad, Faiez, Díez, Javier

“…Myocardial fibrosis is the result of excessive fibrillar collagen synthesis and deposition without reciprocally balanced degradation. It causes cardiac…”
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Opposite Predictive Value of Pulse Pressure and Aortic Pulse Wave Velocity on Heart Failure With Reduced Left Ventricular Ejection Fraction: Insights From an Eplerenone Post–Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS) Substudy by Regnault, Veronique, Lagrange, Jérémy, Pizard, Anne, Safar, Michel E, Fay, Renaud, Pitt, Bertram, Challande, Pascal, Rossignol, Patrick, Zannad, Faiez, Lacolley, Patrick

“…Although hypertension contributes significantly to worsen cardiovascular risk, blood pressure increment in subjects with heart failure is paradoxically…”
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Tailoring mineralocorticoid receptor antagonist therapy in heart failure patients: are we moving towards a personalized approach? by Ferreira, João Pedro, Mentz, Robert J., Pizard, Anne, Pitt, Bertram, Zannad, Faiez

“…The aim of personalized medicine is to offer a tailored approach to each patient in order to provide the most effective therapy, while reducing risks and side…”
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