Search Results - "Pitzer, Claudia"

Behavioral tests assessing neuropsychiatric phenotypes in adolescent mice reveal strain- and sex-specific effects by Eltokhi, Ahmed, Kurpiers, Barbara, Pitzer, Claudia

“…In humans, infancy and adolescence are associated with major changes in synaptic functions and ongoing maturation of neural networks, which underlie the major…”
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Comprehensive characterization of motor and coordination functions in three adolescent wild-type mouse strains by Eltokhi, Ahmed, Kurpiers, Barbara, Pitzer, Claudia

“…Neuropsychiatric disorders are often associated with motor and coordination abnormalities that have important implications on the etiology, pathophysiology,…”
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Gait performance of adolescent mice assessed by the CatWalk XT depends on age, strain and sex and correlates with speed and body weight by Pitzer, Claudia, Kurpiers, Barbara, Eltokhi, Ahmed

“…The automatization of behavioral tests assessing motor activity in rodent models is important for providing robust and reproducible results and evaluating new…”
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Longitudinal analysis of ultrasonic vocalizations in mice from infancy to adolescence: Insights into the vocal repertoire of three wild-type strains in two different social contexts by Peleh, Tatiana, Eltokhi, Ahmed, Pitzer, Claudia

“…Ultrasonic vocalizations (USV) are emitted by mice under certain developmental, social and behavioral conditions. The analysis of USV can be used as a reliable…”
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Sex Differences in Depression-Like Behaviors in Adult Mice Depend on Endophenotype and Strain by Pitzer, Claudia, Kurpiers, Barbara, Eltokhi, Ahmed

“…Depression affects women nearly twice as frequently as men. In contrast, rodent models of depression have shown inconsistent results regarding sex bias, often…”
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Baseline Depression-Like Behaviors in Wild-Type Adolescent Mice Are Strain and Age but Not Sex Dependent by Eltokhi, Ahmed, Kurpiers, Barbara, Pitzer, Claudia

“…Depression is a major neuropsychiatric disorder, decreasing the ability of hundreds of millions of individuals worldwide to function in social, academic, and…”
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Voluntary and evoked behavioral correlates in neuropathic pain states under different social housing conditions by Pitzer, Claudia, Kuner, Rohini, Tappe-Theodor, Anke

“…Background There is an urgent need to develop and incorporate novel behavioral tests in classically used preclinical pain models. Most rodent studies are based…”
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A Fear Memory Engram and Its Plasticity in the Hypothalamic Oxytocin System by Hasan, Mazahir T., Althammer, Ferdinand, Silva da Gouveia, Miriam, Goyon, Stephanie, Eliava, Marina, Lefevre, Arthur, Kerspern, Damien, Schimmer, Jonas, Raftogianni, Androniki, Wahis, Jerome, Knobloch-Bollmann, H. Sophie, Tang, Yan, Liu, Xinying, Jain, Apar, Chavant, Virginie, Goumon, Yannick, Weislogel, Jan-Marek, Hurlemann, René, Herpertz, Sabine C., Pitzer, Claudia, Darbon, Pascal, Dogbevia, Godwin K., Bertocchi, Ilaria, Larkum, Matthew E., Sprengel, Rolf, Bading, Hilmar, Charlet, Alexandre, Grinevich, Valery

“…Oxytocin (OT) release by axonal terminals onto the central nucleus of the amygdala exerts anxiolysis. To investigate which subpopulation of OT neurons…”
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Tspan8 and Tspan8/CD151 knockout mice unravel the contribution of tumor and host exosomes to tumor progression by Zhao, Kun, Wang, Zhe, Hackert, Thilo, Pitzer, Claudia, Zöller, Margot

“…The tetraspanins Tspan8 and CD151 promote metastasis, exosomes (Exo) being suggested to be important in the crosstalk between tumor and host. The contribution…”
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A survey of research quality in core facilities by Kos-Braun, Isabelle C, Gerlach, Björn, Pitzer, Claudia

“…Core facilities are an effective way of making expensive experimental equipment available to a large number of researchers, and are thus well placed to…”
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Establishment of an Olfactory Region-specific Intranasal Delivery Technique in Mice to Target the Central Nervous System by Flamm, Johannes, Hartung, Sunniva, Gänger, Stella, Maigler, Frank, Pitzer, Claudia, Schindowski, Katharina

“…We have recently developed a region-specific catheter-based intranasal application method in mice by using CT scan-based 3D cast models of the murine nose…”
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Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand? by Henriques, Alexandre, Pitzer, Claudia, Schneider, Armin

“…Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that results in progressive loss of motoneurons, motor weakness and death within…”
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Characterization of a novel SOD-1(G93A) transgenic mouse line with very decelerated disease development by Henriques, Alexandre, Pitzer, Claudia, Schneider, Armin

“…Amyotrophic Lateral Sclerosis (ALS) is a fatal motoneuron disease, characterized by progressive weakness, muscle wasting and death ensuing 3-5 years after…”
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Voluntary and evoked behavioral correlates in inflammatory pain conditions under different social housing conditions by Pitzer, Claudia, Kuner, Rohini, Tappe-Theodor, Anke

“…Most preclinical pain models rely on short-duration stimulus-evoked hind paw measurements even though chronic pain is usually a day and night experience. Pain…”
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Nucleolar stress controls mutant Huntington toxicity and monitors Huntington’s disease progression by Sönmez, Aynur, Mustafa, Rasem, Ryll, Salome T., Tuorto, Francesca, Wacheul, Ludivine, Ponti, Donatella, Litke, Christian, Hering, Tanja, Kojer, Kerstin, Koch, Jenniver, Pitzer, Claudia, Kirsch, Joachim, Neueder, Andreas, Kreiner, Grzegorz, Lafontaine, Denis L. J., Orth, Michael, Liss, Birgit, Parlato, Rosanna

“…Transcriptional and cellular-stress surveillance deficits are hallmarks of Huntington’s disease (HD), a fatal autosomal-dominant neurodegenerative disorder…”
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CNS-targeted Viral Delivery of G-CSF in an Animal Model for ALS: Improved Efficacy and Preservation of the Neuromuscular Unit by Henriques, Alexandre, Pitzer, Claudia, Dittgen, Tanjew, Klugmann, Matthias, Dupuis, Luc, Schneider, Armin

“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive loss of motoneurons. We have recently uncovered a new…”
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A neuroprotective function for the hematopoietic protein granulocyte-macrophage colony stimulating factor (GM-CSF) by Schäbitz, Wolf-Rüdiger, Krüger, Carola, Pitzer, Claudia, Weber, Daniela, Laage, Rico, Gassler, Nikolaus, Aronowski, Jaroslaw, Mier, Walter, Kirsch, Friederike, Dittgen, Tanjew, Bach, Alfred, Sommer, Clemens, Schneider, Armin

“…Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a hematopoietic cytokine responsible for the proliferation, differentiation, and maturation of…”
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Selective CNS Targeting and Distribution with a Refined Region-Specific Intranasal Delivery Technique via the Olfactory Mucosa by Maigler, Frank, Ladel, Simone, Flamm, Johannes, Gänger, Stella, Kurpiers, Barbara, Kiderlen, Stefanie, Völk, Ronja, Hamp, Carmen, Hartung, Sunniva, Spiegel, Sebastian, Soleimanizadeh, Arghavan, Eberle, Katharina, Hermann, Rebecca, Krainer, Lukas, Pitzer, Claudia, Schindowski, Katharina

“…Intranasal drug delivery is a promising approach for the delivery of drugs to the CNS, but too heterogenous, unprecise delivery methods without standardization…”
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Granulocyte-colony stimulating factor (G-CSF) improves motor recovery in the rat impactor model for spinal cord injury by Dittgen, Tanjew, Pitzer, Claudia, Plaas, Christian, Kirsch, Friederike, Vogt, Gerhard, Laage, Rico, Schneider, Armin

“…Granulocyte-colony stimulating factor (G-CSF) improves outcome after experimental SCI by counteracting apoptosis, and enhancing connectivity in the injured…”
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Granulocyte-colony stimulating factor improves outcome in a mouse model of amyotrophic lateral sclerosis by Pitzer, Claudia, Krüger, Carola, Plaas, Christian, Kirsch, Friederike, Dittgen, Tanjew, Müller, Ralph, Laage, Rico, Kastner, Stefan, Suess, Stefanie, Spoelgen, Robert, Henriques, Alexandre, Ehrenreich, Hannelore, Schäbitz, Wolf-Rüdiger, Bach, Alfred, Schneider, Armin

“…Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that results in progressive loss of motoneurons, motor weakness and death within…”
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