Search Results - "Pittman, Kenneth"

Randomized Phase III Trial of Temsirolimus Versus Sorafenib As Second-Line Therapy After Sunitinib in Patients With Metastatic Renal Cell Carcinoma by HUTSON, Thomas E, ESCUDIER, Bernard, MOTZER, Robert J, ESTEBAN, Emilio, BJARNASON, Georg A, HO YEONG LIM, PITTMAN, Kenneth B, SENICO, Peggy, NIETHAMMER, Andreas, DONGRUI RAY LU, HARIHARAN, Subramanian

“…This international phase III trial (Investigating Torisel As Second-Line Therapy [INTORSECT]) compared the efficacy of temsirolimus (mammalian target of…”
Get full text

Multiple COVID-19 Clusters on a University Campus - North Carolina, August 2020 by Wilson, Erica, Donovan, Catherine V, Campbell, Margaret, Chai, Thevy, Pittman, Kenneth, Seña, Arlene C, Pettifor, Audrey, Weber, David J, Mallick, Aditi, Cope, Anna, Porterfield, Deborah S, Pettigrew, Erica, Moore, Zack

“…Preventing transmission of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), in institutes of higher education presents a unique set of…”
Get full text

A descriptive study of persistent oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer by Vatandoust, Sina, Joshi, Rohit, Pittman, Kenneth B., Esterman, Adrian, Broadbridge, Vy, Adams, Jacqueline, Singhal, Nimit, Yeend, Susan, Price, Timothy Jay

“…Background Prolonged neurotoxicity after systemic chemotherapy has the potential to impact on quality of life. We explored the frequency of persistent…”
Get full text

Randomized phase II study of carboplatin and paclitaxel with either linifanib or placebo for advanced nonsquamous non-small-cell lung cancer by Ramalingam, Suresh S, Shtivelband, Mikhail, Soo, Ross A, Barrios, Carlos H, Makhson, Anatoly, Segalla, José G M, Pittman, Kenneth B, Kolman, Petr, Pereira, Jose R, Srkalovic, Gordan, Belani, Chandra P, Axelrod, Rita, Owonikoko, Taofeek K, Qin, Qin, Qian, Jiang, McKeegan, Evelyn M, Devanarayan, Viswanath, McKee, Mark D, Ricker, Justin L, Carlson, Dawn M, Gorbunova, Vera A

“…Linifanib, a potent, selective inhibitor of vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) receptors, has single-agent…”
Get full text

Identification of circulating tumour cells in early stage breast cancer patients using multi marker immunobead RT-PCR by Raynor, Michael P, Stephenson, Sally-Anne, Pittman, Kenneth B, Walsh, David C A, Henderson, Michael A, Dobrovic, Alexander

“…The ability to screen blood of early stage operable breast cancer patients for circulating tumour cells is of potential importance for identifying patients at…”
Get full text

Optimisation of the RT-PCR detection of immunomagnetically enriched carcinoma cells by Raynor, Michael, Stephenson, Sally-Anne, Walsh, David C A, Pittman, Kenneth B, Dobrovic, Alexander

“…Immunomagnetic enrichment followed by RT-PCR (immunobead RT-PCR) is an efficient methodology to identify disseminated carcinoma cells in the blood and bone…”
Get full text

Denosumab: Prevention and management of hypocalcemia, osteonecrosis of the jaw and atypical fractures by Pittman, Kenneth, Antill, Yoland C, Goldrick, Amanda, Goh, Jeffrey, Boer, Richard H

“…Denosumab, a bone‐modifying agent, reduces the risk of skeletal‐related events in patients with bone metastases from solid tumors and is generally well…”
Get full text

Pharmacokinetics of didanosine in patients with acquired immunodeficiency syndrome or acquired immunodeficiency syndrome-related complex by Knupp, C A, Shyu, W C, Dolin, R, Valentine, F T, McLaren, C, Martin, R R, Pittman, K A, Barbhaiya, R H

“…The pharmacokinetics of didanosine (2',3'-dideoxyinosine) after intravenous and oral administration were evaluated in an open, escalating-dose phase I study in…”
Get more information

Oral vinorelbine and cisplatin with concomitant radiotherapy in stage III non-small cell lung cancer (NSCLC): COVeRT study by Mislang, Anna Rachelle Austria, Pittman, Kenneth B., Karapetis, Christos Stelios, Stephens, Sonya, Borg, Martin, Singhal, Nimit

“…Abstract only…”
Get full text

Pharmacokinetics of cefepime in subjects with renal insufficiency by Barbhaiya, R H, Knupp, C A, Forgue, S T, Matzke, G R, Guay, D R, Pittman, K A

“…The pharmacokinetics of intravenously administered cefepime (1000 mg over 30 minutes) were studied in 5 healthy volunteers and 20 patients with various degrees…”
Get more information

Oral vinorelbine and cisplatin with concomitant radiotherapy in stage III non-small-cell lung cancer: an open-label phase II multicentre trial (COVeRT study) by Singhal, Nimit, Mislang, Anna, Karapetis, Christos S, Stephens, Sonya, Borg, Martin, Woodman, Richard J, Pittman, Kenneth

“…Chemoradiotherapy regimens for stage III non-small-cell lung cancer (NSCLC) require ongoing evaluation. This South Australian multicentre prospective phase II…”
Get full text

Food-induced reduction in bioavailability of didanosine by Shyu, W C, Knupp, C A, Pittman, K A, Dunkle, L, Barbhaiya, R H

“…The effect of food on the pharmacokinetics of didanosine was evaluated in an open two-way crossover study in eight male subjects who tested seropositive for…”
Get more information

Symptomatic skeletal events (SSE) in patients with advanced prostate cancer: Results from a phase III trial of denosumab for the prevention of skeletal-related events by Klotz, Laurence, Smith, Matthew Raymond, Coleman, Robert E., Pittman, Kenneth B., Milecki, Piotr, Wei, Rachel, Balakumaran, Arun, Fizazi, Karim

“…Abstract only…”
Get full text

Denosumab for the prevention of symptomatic skeletal events in patients with castration-resistant advanced prostate cancer: A comparison with skeletal-related events by Smith, Matthew R., Coleman, Robert E., Klotz, Laurence, Pittman, Kenneth B., Milecki, Piotr, Wei, Rachel, Balakumaran, Arun, Fizazi, Karim

“…Abstract only 35 Background: In a randomized controlled trial of men with castration-resistant prostate cancer (CRPC) and bone metastases, denosumab was…”
Get full text

Denosumab: Prevention and management of hypocalcemia, osteonecrosis of the jaw and atypical fractures: Denosumab: rare toxicities by Pittman, Kenneth, Antill, Yoland C, Goldrick, Amanda, Goh, Jeffrey, de Boer, Richard H

Get full text

Oral vinorelbine and cisplatin with concomitant radiotherapy in stage III non-small cell lung cancer (NSCLC): COVeRT study by Singhal, Nimit, Pittman, Kenneth B., Karapetis, Christos Stelios, Stephens, Sonya, Borg, Martin

“…Abstract only e17544 Background: Chemoradiation is standard of care for the treatment of stage III NSCLC. Vinorelbine has been widely used for the treatment in…”
Get full text

Multiple-dose phase I study of transnasal butorphanol by Shyu, W C, Pittman, K A, Robinson, D, Barbhaiya, R H

“…The safety, tolerance, and pharmacokinetics of transnasal butorphanol were evaluated in a double-blind, multiple-dose phase I study. A total of 18 subjects…”
Get more information

Persistent oxaliplatin (OX) induced peripheral neuropathy in patients (pts) with colorectal cancer: A descriptive study by Vatandoust, Sina, Joshi, Rohit, Broadbridge, Vy, Pittman, Kenneth B., Adams, Jacqueline, Singhal, Nimit, Colbeck, Margaret, Yeend, Susan, Price, Timothy Jay

“…Abstract only e19513 Background: Available data suggest that the OX-induced neuropathy is usually reversible and a minority of pts will have persistent severe…”
Get full text

Final overall survival analysis for the RECORD-3 study of first-line everolimus followed by sunitinib versus first-line sunitinib followed by everolimus in metastatic RCC (mRCC) by Knox, Jennifer J., Barrios, Carlos H., Kim, Tae Min, Cosgriff, Thomas, Srimuninnimit, Vichien, Pittman, Kenneth B., Sabbatini, Roberto, Rha, Sun Young, Flaig, Thomas W., Page, Ray D., Beck, J. Thaddeus, Cheung, Foon yiu, Yadav, Sunil, Patel, Poulam M., Geoffrois, Lionnel, Schiff, Edward, Niolat, Julie, Berkowitz, Noah, Voi, Maurizio, Motzer, Robert

“…Abstract only…”
Get full text

Reversing Hyperammonemia in Neuroendocrine Tumors by Broadbridge, Vy, Townsend, Amanda, Pittman, Kenneth, Kimber, Richard, Patterson, William, Sukumaran, Shawgi, Price, Timothy J

“…Ammonia is a neurotoxin that is normally cleared by the intact liver and if not, hyperammonemia results in hepatic encephalopathy. Hyperammonemia may be owing…”
Get full text