Search Results - "Pittet, Camille L"

Targeting the GM-CSF receptor for the treatment of CNS autoimmunity by Ifergan, Igal, Davidson, Todd S, Kebir, Hania, Xu, Dan, Palacios-Macapagal, Daphne, Cann, Jennifer, Rodgers, Jane M, Hunter, Zoe N, Pittet, Camille L, Beddow, Sara, Jones, Clare A, Prat, Alexandre, Sleeman, Matthew A, Miller, Stephen D

“…Abstract In multiple sclerosis (MS), there is a growing interest in inhibiting the pro-inflammatory effects of granulocyte-macrophage colony-stimulating factor…”
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Human brain endothelial cells endeavor to immunoregulate CD8 T cells via PD-1 ligand expression in multiple sclerosis by Pittet, Camille L, Newcombe, Jia, Prat, Alexandre, Arbour, Nathalie

“…Multiple sclerosis (MS), an inflammatory disease of the central nervous system (CNS), is characterized by blood-brain barrier (BBB) disruption and massive…”
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An optimized method to process mouse CNS to simultaneously analyze neural cells and leukocytes by flow cytometry by Legroux, Laurine, Pittet, Camille L., Beauseigle, Diane, Deblois, Gabrielle, Prat, Alexandre, Arbour, Nathalie

“…•Digestion with collagenase D+DNAse I is optimal to isolate neural and immune cells from mouse CNS.•One step Percoll is superior to Percoll gradient to isolate…”
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Contribution of astrocyte-derived IL-15 to CD8 T cell effector functions in multiple sclerosis by Saikali, Philippe, Antel, Jack P, Pittet, Camille L, Newcombe, Jia, Arbour, Nathalie

“…The contribution of local factors to the activation of immune cells infiltrating the CNS of patients with multiple sclerosis (MS) remains to be defined. The…”
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The majority of infiltrating CD8 T lymphocytes in multiple sclerosis lesions is insensitive to enhanced PD-L1 levels on CNS cells by Pittet, Camille L., Newcombe, Jia, Antel, Jack P., Arbour, Nathalie

“…Central nervous system (CNS) cells locally modulate immune responses using numerous molecules that are not fully elucidated. Engagement of programmed death‐1…”
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Humanized mouse model of Rasmussen's encephalitis supports the immune-mediated hypothesis by Kebir, Hania, Carmant, Lionel, Fontaine, François, Béland, Kathie, Bosoi, Ciprian M, Sanon, Nathalie T, Alvarez, Jorge I, Desgent, Sébastien, Pittet, Camille L, Hébert, David, Langlois, Marie-Josée, Rébillard, Rose-Marie, Nguyen, Dang K, Cieuta-Walti, Cécile, Holmes, Gregory L, Goodkin, Howard P, Mytinger, John R, Connolly, Mary B, Prat, Alexandre, Haddad, Elie

“…Rasmussen's encephalitis (RE) is a chronic inflammatory brain disorder that causes frequent seizures and unilateral hemispheric atrophy with progressive…”
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