Search Results - "Pittenger, Steven T"

Acetylcholine is released in the basolateral amygdala in response to predictors of reward and enhances the learning of cue-reward contingency by Crouse, Richard B, Kim, Kristen, Batchelor, Hannah M, Girardi, Eric M, Kamaletdinova, Rufina, Chan, Justin, Rajebhosale, Prithviraj, Pittenger, Steven T, Role, Lorna W, Talmage, David A, Jing, Miao, Li, Yulong, Gao, Xiao-Bing, Mineur, Yann S, Picciotto, Marina R

“…The basolateral amygdala (BLA) is critical for associating initially neutral cues with appetitive and aversive stimuli and receives dense neuromodulatory…”
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MicroRNA cluster miR199a/214 are differentially expressed in female and male rats following nicotine self-administration by Pittenger, Steven T., Schaal, Victoria L., Moore, Dalia, Guda, Rahul S., Koul, Sneh, Yelamanchili, Sowmya V., Bevins, Rick A., Pendyala, Gurudutt

“…Previous research has established sex differences associated with nicotine intake, however a significant gap in knowledge remains regarding the molecular…”
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Role of Brain Derived Extracellular Vesicles in Decoding Sex Differences Associated with Nicotine Self-Administration by Koul, Sneh, Schaal, Victoria L, Chand, Subhash, Pittenger, Steven T, Nanoth Vellichirammal, Neetha, Kumar, Vikas, Guda, Chittibabu, Bevins, Rick A, Yelamanchili, Sowmya V, Pendyala, Gurudutt

“…Smoking remains a significant health and economic concern in the United States. Furthermore, the emerging pattern of nicotine intake between sexes further adds…”
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Conditioned Enhancement of the Nicotine Reinforcer by Charntikov, Sergios, Pittenger, Steven T., Swalve, Natashia, Barrett, Scott T., Bevins, Rick A.

“…This study was designed to assess whether nicotine can acquire additional reinforcing properties through associations with other rewards. To this end, rats…”
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The effect of N-acetylcysteine or bupropion on methamphetamine self-administration and methamphetamine–triggered reinstatement of female rats by Charntikov, Sergios, Pittenger, Steven T., Pudiak, Cindy M., Bevins, Rick A.

“…N-acetylcysteine and bupropion are two promising candidate medications for treatment of substance use disorder. The effects of N-acetylcysteine or bupropion on…”
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ACh signaling modulates activity of the GABAergic signaling network in the basolateral amygdala and behavior in stress-relevant paradigms by Mineur, Yann S., Mose, Tenna N., Maibom, Kathrine Lefoli, Pittenger, Steven T., Soares, Alexa R., Wu, Hao, Taylor, Seth R., Huang, Yaqing, Picciotto, Marina R.

“…The balance between excitatory and inhibitory (E/I) signaling is important for maintaining homeostatic function in the brain. Indeed, dysregulation of…”
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Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors by Lewis, Alan S, Pittenger, Steven T, Mineur, Yann S, Stout, Dawson, Smith, Philip H, Picciotto, Marina R

“…Humans with 15q13.3 microdeletion syndrome (15q13.3DS) are typically hemizygous for CHRNA7, the gene coding for the α7 nicotinic acetylcholine receptor…”
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Double dissociation of the anterior and posterior dorsomedial caudate-putamen in the acquisition and expression of associative learning with the nicotine stimulus by Charntikov, Sergios, Pittenger, Steven T., Swalve, Natashia, Li, Ming, Bevins, Rick A.

“…Tobacco use is the leading cause of preventable deaths worldwide. This habit is not only debilitating to individual users but also to those around them…”
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Female rats display higher methamphetamine-primed reinstatement and c-Fos immunoreactivity than male rats by Pittenger, Steven T., Chou, Shinnyi, Murawski, Nathen J., Barrett, Scott T., Loh, Olivia, Duque, Juan F., Li, Ming, Bevins, Rick A.

“…Methamphetamine (meth) dependence is often characterized by persistent and chronic relapse (i.e., return to drug use). Previous work suggests females may be at…”
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The effects of varenicline on methamphetamine self-administration and drug-primed reinstatement in male rats by Pittenger, Steven T., Barrett, Scott T., Chou, Shinnyi, Bevins, Rick A.

“…Methamphetamine (meth) addiction is a costly burden to both the individual user and society as a whole. Establishing effective pharmacotherapies to treat meth…”
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Ibudilast reverses the decrease in the synaptic signaling protein phosphatidylethanolamine-binding protein 1 (PEBP1) produced by chronic methamphetamine intake in rats by Charntikov, Sergios, Pittenger, Steven T, Thapa, Ishwor, Bastola, Dhundy R, Bevins, Rick A, Pendyala, Gurudutt

“…Graphical abstract…”
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Behavioral effects of phencyclidine on nicotine self-administration and reinstatement in the presence or absence of a visual stimulus in rats by Swalve, Natashia, Pittenger, Steven T., Bevins, Rick A., Li, Ming

“…Rationale Tobacco use is a serious health problem in the USA, and this problem is potentiated in patients with schizophrenia. The reward system is implicated…”
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The effects of varenicline on methamphetamine self-administration and drug-primed reinstatement in female rats by Pittenger, Steven T., Barrett, Scott T., Chou, Shinnyi, Bevins, Rick A.

“…•Female Sprague-Dawley rats readily self-administered methamphetamine.•Varenicline attenuated responding during self-administration.•Female rats displayed…”
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Sex Differences in the Reward-Enhancing Effects of Nicotine on Ethanol Reinforcement: A Reinforcer Demand Analysis by Barrett, Scott T, Thompson, Brady M, Emory, Jessica R, Larsen, Chris E, Pittenger, Steven T, Harris, Edward N, Bevins, Rick A

“…Abstract Background Alcohol is often consumed with tobacco, and dependence to alcohol and tobacco are highly comorbid. In addition, there are differences in…”
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Nicotine- and cocaine-triggered methamphetamine reinstatement in female and male Sprague-Dawley rats by Pittenger, Steven T., Chou, Shinnyi, Barrett, Scott T., Catalano, Isabella, Lydiatt, Maxwell, Bevins, Rick A.

“…Preclinical studies have demonstrated a return to methamphetamine (meth)-seeking behavior (reinstatement) induced by injections of meth administered by the…”
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Interoceptive Conditioning With a Nicotine Stimulus Is Susceptible to Reinforcer Devaluation by Pittenger, Steven T, Bevins, Rick A

“…Pavlovian conditioning processes contribute to the etiology of nicotine dependence. Conditioning involving interoceptive stimuli is increasingly recognized as…”
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Activity of a direct VTA to ventral pallidum GABA pathway encodes unconditioned reward value and sustains motivation for reward by Zhou, Wen-Liang, Kim, Kristen, Ali, Farhan, Pittenger, Steven T, Calarco, Cali A, Mineur, Yann S, Ramakrishnan, Charu, Deisseroth, Karl, Kwan, Alex C, Picciotto, Marina R

“…Dopamine signaling from the ventral tegmental area (VTA) plays critical roles in reward-related behaviors, but less is known about the functions of neighboring…”
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Induction of reversible bidirectional social approach bias by olfactory conditioning in male mice by Chan, Justin, Stout, Dawson, Pittenger, Steven T., Picciotto, Marina R., Lewis, Alan S.

“…Social avoidance is a common component of neuropsychiatric disorders that confers substantial functional impairment. An unbiased approach to identify brain…”
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The effect of switching pharmacological intervention during extinction on nicotine-evoked conditioned responding in rats by Pittenger, Steven T., Zeplin, Lindsey C., Dwoskin, Linda P., Bevins, Rick A.

“…Rationale Pharmacotherapies are often utilized to aid in smoking cessation, and switching medication when treating nicotine dependence has become more…”
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Interoceptive conditioning in rats: Effects of using a single training dose or a set of 5 different doses of nicotine by Pittenger, Steven T., Bevins, Rick A.

“…Interoceptive conditioning contributes to the tenacity of nicotine dependence. Previous research investigating nicotine as an interoceptive stimulus has…”
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