Search Results - "Pitner, J B"

Using Receptor Conformational Change To Detect Low Molecular Weight Analytes by Surface Plasmon Resonance by Gestwicki, Jason E, Hsieh, Helen V, Pitner, J. Bruce

“…Small molecules are difficult to directly detect using commercially available surface plasmon resonance (SPR) instruments. This is because low molecular weight…”
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Synthesis of Thiol-Reactive, Long-Wavelength Fluorescent Phenoxazine Derivatives for Biosensor Applications by Sherman, Douglas B, Pitner, J. Bruce, Ambroise, Arounaguiry, Thomas, K. Joseph

“…Two environmentally sensitive, long-wavelength fluorescent phenoxazine derivatives, INR and IANR, were synthesized with linkers for conjugation to the thiol…”
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The nucleic acid ligand. A new tool for molecular recognition by McGown, Linda B, Joseph, Melissa J, Pitner, J. Bruce, vonk, Glenn P, Linn, C. Preston

“…Oligonucleotide ligands can provide specific and high-affinity binding with selected target molecules. The chemistry of nucleic acid ligands is described, and…”
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Novel fluorescent technology platform for high throughput cytotoxicity and proliferation assays by Wodnicka, M, Guarino, R D, Hemperly, J J, Timmins, M R, Stitt, D, Pitner, J B

“…We have developed a novel fluorescent Oxygen BioSensor technology platform adaptable to many applications in the area of drug discovery and development,…”
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Synthesis, molecular modeling studies, and muscarinic receptor activity of azaprophen analogs by Triggle, David J, Kwon, Yong Who, Abraham, Philip, Pitner, J. Bruce, Mascarella, S. Wayne, Carroll, F. I

“…Synthesis, radioligand binding, and pharmacologic activities of a series of muscarinic receptor ligands including and related to azaprophen…”
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Synthesis of serine-AMC-carbamate: a fluorogenic tryptophanase substrate by Linn, C P, Mize, P D, Hoke, R A, Quante, J M, Pitner, J B

“…A new fluorogenic substrate for the pyridoxal 5'-phosphate-dependent enzyme tryptophanase is described. L-Serine, which is linked to 7-amino-4-methylcoumarin…”
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Real-Time, Sequence-Specific Detection of Nucleic Acids during Strand Displacement Amplification by Nadeau, James G., Pitner, J.Bruce, Linn, C.Preston, Schram, James L., Dean, Cheryl H., Nycz, Colleen M.

“…Strand displacement amplification (SDA) is an isothermal nucleic acid amplification method based on the primer-directed nicking activity of a restriction…”
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Transferred Nuclear Overhauser Enhancement Experiments Show That the Monoclonal Antibody Strep 9 Selects a Local Minimum Conformation of a Streptococcus Group A Trisaccharide-Hapten by Weimar, Thomas, Harris, Shannon L., Pitner, J. Bruce, Bock, Klaus, Pinto, B. Mario

“…Transferred nuclear Overhauser enhancement (TRNOE) experiments have been performed to investigate the bound conformation of the trisaccharide repeating unit of…”
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Bivalency and epitope specificity of a high-affinity IgG3 monoclonal antibody to the Streptococcus Group A carbohydrate antigen. Molecular modeling of a Fv fragment by Pitner, J.Bruce, Beyer, Wayne F., Venetta, Thomas M., Nycz, Colleen, Mitchell, Michael J., Harris, Shannon L., Mariño-Albernas, Jose R., Auzanneau, France-Isabelle, Forooghian, Farzin, Mario Pinto, B.

“…The binding of Strep 9, a mouse monoclonal antibody (mAb) of the IgG3 subclass directed against the cell-wall polysaccharide of Group A Streptococcus (GAS),…”
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N-Modified analogs of cocaine: synthesis and inhibition of binding to the cocaine receptor by Abraham, Philip, Pitner, J. Bruce, Lewin, Anita H, Boja, John W, Kuhar, Michael J, Carroll, F. Ivy

“…Cocaine methiodide (2), N-norcocaine (1b), N-benzyl-N-norcocaine (1c), and N-nor-N-acetylcocaine (1d) were synthesized and evaluated for their ability to…”
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Spectroscopic studies of single-stranded DNA ligands and oxazole yellow dyes by Abramo, Kimberly H., Pitner, J. Bruce, McGown, Linda B.

“…Interactions between short single‐stranded DNA ligands and fluorescent DNA indicator dyes were used to investigate binding selectivity of the ligands…”
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Direct detection of glucose by surface plasmon resonance with bacterial glucose/galactose-binding protein by Hsieh, Helen V, Pfeiffer, Zachary A, Amiss, Terry J, Sherman, Douglas B, Pitner, J.Bruce

“…The monitoring and management of blood glucose levels are key components for maintaining the health of people with diabetes. Traditionally, glucose monitoring…”
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Method for determining oxygen consumption rates of static cultures from microplate measurements of pericellular dissolved oxygen concentration by Guarino, Richard D., Dike, Laura E., Haq, Tariq A., Rowley, Jon A., Pitner, J. Bruce, Timmins, Mark R.

“…We describe a simple protocol for determining the oxygen consumption of cells in static culture. The protocol is based on a noninvasive oxygen‐sensing…”
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Atmospheric sulfur as related to fertility of Ultisols and Entisols in South Carolina [Acid rain, crop response] by Jones, U. S., Hamilton, M. G., Pitner, J. B.

“…Contributions of atmospheric sulfur (S) to soil fertility at 15 locations in South Carolina were estimated during the 5‐year period 1973–77 by measuring the S…”
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Temperature and Quenching Studies of Fluorescence Polarization Detection of DNA Hybridization by Kumke, Michael U, Shu, Luchuan, McGown, Linda B, Walker, G. Terrance, Pitner, J. Bruce, Linn, C. Preston

“…The effects of temperature and collisional quenching on fluorescence polarization detection of DNA hybridization were studied using measurements of…”
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Method for determining oxygen consumption rates of static cultures from microplate measurements of pericellular dissolved oxygen concentration by Guarino, Richard D., Dike, Laura E., Haq, Tariq A., Rowley, Jon A., Pitner, J. Bruce, Timmins, Mark R.

“…The original article to which this Erratum refers was published in Biotechnol Bioeng 2004;86:775–787…”
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Evaluation of the relative stability of liganded versus ligand-free protein conformations using Simplicial Neighborhood Analysis of Protein Packing (SNAPP) method by Sherman, Douglas B., Zhang, Shuxing, Pitner, J. Bruce, Tropsha, Alexander

“…Many proteins change their conformation upon ligand binding. For instance, bacterial periplasmic binding proteins (bPBPs), which transport nutrients into the…”
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Studies in biomimetic alkaloid syntheses. XVII: Syntheses of iboxyphyline and related alkaloids by KUEHNE, M. E, PITNER, J. B

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Spectroscopic studies of YO and YOYO fluorescent dyes in a thrombin-binding DNA ligand by Joseph, Melissa J., Taylor, Jonathan C., McGown, Linda B., Pitner, J. Bruce, Linn, C. Preston

“…The fluorescent, oxazole yellow dye YO‐Pro‐1 iodide (YO) and its homodimer YOYO‐1 iodide (YOYO) were studied in a thrombin‐binding DNA ligand, or aptamer,…”
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Studies in biomimetic alkaloid syntheses. 17. Syntheses of iboxyphylline and related alkaloids by Kuehne, Martin E, Pitner, J. Bruce

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