Search Results - "Pithadia, Amit"

Metal-associated amyloid-β species in Alzheimer's disease by Pithadia, Amit S, Lim, Mi Hee

“…[Display omitted] ► Generation and aggregation of amyloid-β, as well as its interaction/reactivity with metal ions in Alzheimer's disease. ► Involvement of…”
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Influence of a curcumin derivative on hIAPP aggregation in the absence and presence of lipid membranes by Pithadia, Amit S, Bhunia, Anirban, Sribalan, Rajendran, Padmini, Vediappen, Fierke, Carol A, Ramamoorthy, Ayyalusamy

“…The deposition of aggregates of human islet amyloid polypeptide (hIAPP) has been correlated with the death of β-cells in type II diabetes mellitus. The actual…”
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In Search of Aggregation Pathways of IAPP and Other Amyloidogenic Proteins: Finding Answers through NMR Spectroscopy by Patel, Hiren R, Pithadia, Amit S, Brender, Jeffrey R, Fierke, Carol A, Ramamoorthy, Ayyalusamy

“…The deposition of aggregates of human islet amyloid peptide (hIAPP) has been correlated with the death of insulin-producing beta (β) cells in type II diabetes…”
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Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly by Sharkey, Lisa M., Safren, Nathaniel, Pithadia, Amit S., Gerson, Julia E., Dulchavsky, Mark, Fischer, Svetlana, Patel, Ronak, Lantis, Gabrielle, Ashraf, Naila, Kim, John H., Meliki, Alia, Minakawa, Eiko N., Barmada, Sami J., Ivanova, Magdalena I., Paulson, Henry L.

“…UBQLN2 is one of a family of proteins implicated in ubiquitin-dependent protein quality control and integrally tied to human neurodegenerative disease. Whereas…”
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Inhibition of IAPP Aggregation and Toxicity by Natural Products and Derivatives by Ramamoorthy, Ayyalusamy, Fierke, Carol A., Brender, Jeffrey R., Pithadia, Amit

“…Fibrillar aggregates of human islet amyloid polypeptide, hIAPP, a pathological feature seen in some diabetes patients, are a likely causative agent for…”
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Self-Assembly of a Nine-Residue Amyloid-Forming Peptide Fragment of SARS Corona Virus E‑Protein: Mechanism of Self Aggregation and Amyloid-Inhibition of hIAPP by Ghosh, Anirban, Pithadia, Amit S, Bhat, Jyotsna, Bera, Supriyo, Midya, Anupam, Fierke, Carol A, Ramamoorthy, Ayyalusamy, Bhunia, Anirban

“…Molecular self-assembly, a phenomenon widely observed in nature, has been exploited through organic molecules, proteins, DNA, and peptides to study complex…”
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Kinetics and thermodynamics of metal‐binding to histone deacetylase 8 by Kim, Byungchul, Pithadia, Amit S., Fierke, Carol A.

“…Histone deacetylase 8 (HDAC8) was originally classified as a Zn(II)‐dependent deacetylase on the basis of Zn(II)‐dependent HDAC8 activity in vitro and…”
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RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control by Mohan, Harihar Milaganur, Trzeciakiewicz, Hanna, Pithadia, Amit, Crowley, Emily V., Pacitto, Regina, Safren, Nathaniel, Trotter, Bryce, Zhang, Chengxin, Zhou, Xiaogen, Zhang, Yang, Basrur, Venkatesha, Paulson, Henry L., Sharkey, Lisa M.

“…The brain-expressed ubiquilins (UBQLNs) 1, 2 and 4 are a family of ubiquitin adaptor proteins that participate broadly in protein quality control (PQC)…”
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Tuning Reactivity of Diphenylpropynone Derivatives with Metal-Associated Amyloid‑β Species via Structural Modifications by Liu, Yuzhong, Kochi, Akiko, Pithadia, Amit S, Lee, Sanghyun, Nam, Younwoo, Beck, Michael W, He, Xiaoming, Lee, Dongkuk, Lim, Mi Hee

“…A diphenylpropynone derivative, DPP2, has been recently demonstrated to target metal-associated amyloid-β (metal–Aβ) species implicated in Alzheimer’s disease…”
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Reactivity of Diphenylpropynone Derivatives Toward Metal-Associated Amyloid‑β Species by Pithadia, Amit S, Kochi, Akiko, Soper, Molly T, Beck, Michael W, Liu, Yuzhong, Lee, Sanghyun, DeToma, Alaina S, Ruotolo, Brandon T, Lim, Mi Hee

“…In Alzheimer’s disease (AD), metal-associated amyloid-β (metal–Aβ) species have been suggested to be involved in neurotoxicity; however, their role in disease…”
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INVESTIGATING THE ROLE OF UBIQUILIN2 IN AGE-RELATED NEURODEGENERATION by Sharkey, Lisa M., Safren, Nate, Pithadia, Amit, Gerson, Julia E., Dulchavsky, Mark E., Fischer, Svetlana, Patel, Ronak, Lantis, Gabrielle, Ashraf, Naila, Barmada, Sami, Ivanova, Magdalena, Paulson, Henry L.

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P3‐152: INVESTIGATING THE ROLE OF UBIQUILIN2 IN AGE‐RELATED NEURODEGENERATION by Sharkey, Lisa M., Safren, Nate, Pithadia, Amit, Gerson, Julia E., Dulchavsky, Mark E., Fischer, Svetlana, Patel, Ronak, Lantis, Gabrielle, Ashraf, Naila, Barmada, Sami, Ivanova, Magdalena, Paulson, Henry L.

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Self-Assembly of a 9-Residue Amyloid-Forming Peptide Fragment of SARS Corona Virus E-protein: Mechanism of Self Aggregation and Amyloid-Inhibition of hIAPP by Ghosh, Anirban, Pithadia, Amit S., Bhat, Jyotsna, Bera, Supriyo, Midya, Anupam, Fierke, Carol A., Ramamoorthy, Ayyalusamy, Bhunia, Anirban

“…Molecular self-assembly, a phenomenon widely observed in nature, has been exploited through organic molecules, proteins, DNA and peptides to study complex…”
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INVESTIGATING THE ROLE OF UBIQUILIN2 IN AGE-RELATED NEURODEGENERATION by Paulson, Henry L., Sharkey, Lisa M., Safren, Nate, Pithadia, Amit, Fischer, Svetlana, Zeng, Li, Dulchavsky, Mark E., Patel, Ronak, Lantis, Gabrielle, Barmada, Sami, Ivanova, Magdalena

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Using Small Molecules and Peptides as Chemical Tools to Study Metal-Amyloid, Membrane-Amyloid, and Peptide-Amyloid Interactions by Pithadia, Amit S

“…Amyloid proteins are a family a proteins that are characterized by the misfolding an intrinsically disordered monomer subunit into an ordered beta-sheet…”
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Overcoming Matrix Effects in a Complex Sample: Analysis of Multiple Elements in Multivitamins by Atomic Absorption Spectroscopy by Arnold, Randy J, Arndt, Brett, Blaser, Emilia, Blosser, Chris, Caulton, Dana, Chung, Won Sog, Fiorenza, Garrett, Heath, Wyatt, Jacobs, Alex, Kahng, Eunice, Koh, Eun, Le, Thao, Mandla, Kyle, McCory, Chelsey, Newman, Laura, Pithadia, Amit, Reckelhoff, Anna, Rheinhardt, Joseph, Skljarevski, Sonja, Stuart, Jordyn, Taylor, Cassie, Thomas, Scott, Tse, Kyle, Wall, Rachel, Warkentien, Chad

“…A multivitamin tablet and liquid are analyzed for the elements calcium, magnesium, iron, zinc, copper, and manganese using atomic absorption spectrometry…”
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Using Small Molecules and Peptides as Chemical Tools to Study Metal-Amyloid, Membrane-Amyloid, and Peptide-Amyloid Interactions by Pithadia, Amit S

“…Amyloid proteins are a family a proteins that are characterized by the misfolding an intrinsically disordered monomer subunit into an ordered beta-sheet…”
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