Search Results - "Pistis, Giorgio"

Obesity and atypical depression symptoms: findings from Mendelian randomization in two European cohorts by Pistis, Giorgio, Milaneschi, Yuri, Vandeleur, Caroline L., Lasserre, Aurélie M., Penninx, Brenda W.J.H., Lamers, Femke, Boomsma, Dorret I., Hottenga, Jouke-Jan, Marques-Vidal, Pedro, Vollenweider, Peter, Waeber, Gérard, Aubry, Jean-Michel, Preisig, Martin, Kutalik, Zoltán

“…Studies considering the causal role of body mass index (BMI) for the predisposition of major depressive disorder (MDD) based on a Mendelian Randomization (MR)…”
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Increased serum hepcidin levels in subjects with the metabolic syndrome: a population study by Martinelli, Nicola, Traglia, Michela, Campostrini, Natascia, Biino, Ginevra, Corbella, Michela, Sala, Cinzia, Busti, Fabiana, Masciullo, Corrado, Manna, Daniele, Previtali, Sara, Castagna, Annalisa, Pistis, Giorgio, Olivieri, Oliviero, Toniolo, Daniela, Camaschella, Clara, Girelli, Domenico

“…The recent discovery of hepcidin, the key iron regulatory hormone, has changed our view of iron metabolism, which in turn is long known to be linked with…”
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Prediction of antipsychotics efficacy based on a polygenic risk score: a real-world cohort study by De Pieri, Marco, Ferrari, Marco, Pistis, Giorgio, Gamma, Franziska, Marino, Franca, Von Gunten, Armin, Conus, Philippe, Cosentino, Marco, Eap, Chin-Bin

“…Response to antipsychotics is subject to a wide interindividual variability, due to genetic and non-genetic factors. Several single nucleotide polymorphisms…”
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Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk by Miles, Amy E, Dos Santos, Fernanda C, Byrne, Enda M, Renteria, Miguel E, McIntosh, Andrew M, Adams, Mark J, Pistis, Giorgio, Castelao, Enrique, Preisig, Martin, Baune, Bernhard T, Schubert, K Oliver, Lewis, Cathryn M, Jones, Lisa A, Jones, Ian, Uher, Rudolf, Smoller, Jordan W, Perlis, Roy H, Levinson, Douglas F, Potash, James B, Weissman, Myrna M, Shi, Jianxin, Lewis, Glyn, Penninx, Brenda W J H, Boomsma, Dorret I, Hamilton, Steven P, Sibille, Etienne, Hariri, Ahmad R, Nikolova, Yuliya S

“…Studies in post-mortem human brain tissue have associated major depressive disorder (MDD) with cortical transcriptomic changes, whose potential in vivo impact…”
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Cholesterol-metabolism, plant sterols, and long-term cognitive decline in older people – Effects of sex and APOEe4 by Spinedi, Matteo, Clark, Christopher, Zullo, Leonardo, Kerksiek, Anja, Pistis, Giorgio, Castelao, Enrique, von Gunten, Armin, Preisig, Martin, Lütjohann, Dieter, Popp, Julius

“…Neurodegenerative, vascular, and dementia diseases are linked to dysregulations in cholesterol metabolism. Dietary plant sterols, or phytosterols, may…”
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Association analysis of bitter receptor genes in five isolated populations identifies a significant correlation between TAS2R43 variants and coffee liking by Pirastu, Nicola, Kooyman, Maarten, Traglia, Michela, Robino, Antonietta, Willems, Sara M, Pistis, Giorgio, d'Adamo, Pio, Amin, Najaf, d'Eustacchio, Angela, Navarini, Luciano, Sala, Cinzia, Karssen, Lennart C, van Duijn, Cornelia, Toniolo, Daniela, Gasparini, Paolo

“…Coffee, one of the most popular beverages in the world, contains many different physiologically active compounds with a potential impact on people's health…”
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Environmental factors in offspring of parents with mood disorders and their role in parent–child transmission: findings from a 14-year prospective high-risk study by Moulin, Flore, Gholam, Mehdi, Strippoli, Marie-Pierre F., Castelao, Enrique, Merikangas, Kathleen R., Stapp, Emma K., Marquet, Pierre, Aubry, Jean-Michel, Plessen, Kerstin J., Di Giacomo, Francesca, Glaus, Jennifer, Pistis, Giorgio, Lavigne, Benjamin, Elowe, Julien, Ranjbar, Setareh, Preisig, Martin, Vandeleur, Caroline L.

“…Background The factors involved in the transmission of mood disorders are only partially elucidated. Aside from genes, the family environment might play a…”
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Heritability and demographic analyses in the large isolated population of Val Borbera suggest advantages in mapping complex traits genes by Traglia, Michela, Sala, Cinzia, Masciullo, Corrado, Cverhova, Valeria, Lori, Francesca, Pistis, Giorgio, Bione, Silvia, Gasparini, Paolo, Ulivi, Sheila, Ciullo, Marina, Nutile, Teresa, Bosi, Emanuele, Sirtori, Marcella, Mignogna, Giovanna, Rubinacci, Alessandro, Buetti, Iwan, Camaschella, Clara, Petretto, Enrico, Toniolo, Daniela

“…Isolated populations are a useful resource for mapping complex traits due to shared stable environment, reduced genetic complexity and extended Linkage…”
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Correction: Increased Serum Hepcidin Levels in Subjects with the Metabolic Syndrome: A Population Study by Martinelli, Nicola, Traglia, Michela, Campostrini, Natascia, Biino, Ginevra, Corbella, Michela, Sala, Cinzia, Busti, Fabiana, Masciullo, Corrado, Manna, Daniele, Previtali, Sara, Castagna, Annalisa, Pistis, Giorgio, Olivieri, Oliviero, Toniolo, Daniela, Camaschella, Clara, Girelli, Domenico

“…[This corrects the article on p. e48250 in vol. 7.]…”
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Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans by Pistis, Giorgio, Okonkwo, Shawntel U, Traglia, Michela, Sala, Cinzia, Shin, So-Youn, Masciullo, Corrado, Buetti, Iwan, Massacane, Roberto, Mangino, Massimo, Thein, Swee-Lay, Spector, Timothy D, Ganesh, Santhi, Pirastu, Nicola, Gasparini, Paolo, Soranzo, Nicole, Camaschella, Clara, Hart, Daniel, Green, Michael R, Toniolo, Daniela

“…The red blood cell related traits are highly heritable but their genetics are poorly defined. Only 5-10% of the total observed variance is explained by the…”
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High differentiation among eight villages in a secluded area of Sardinia revealed by genome-wide high density SNPs analysis by Pistis, Giorgio, Piras, Ignazio, Pirastu, Nicola, Persico, Ivana, Sassu, Alessandro, Picciau, Andrea, Prodi, Dionigio, Fraumene, Cristina, Mocci, Evelina, Manias, Maria Teresa, Atzeni, Rossano, Cosso, Massimiliano, Pirastu, Mario, Angius, Andrea

“…To better design association studies for complex traits in isolated populations it's important to understand how history and isolation moulded the genetic…”
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Minimal phenotyping yields genome-wide association signals of low specificity for major depression by Cai, Na, Revez, Joana A., Adams, Mark J., Andlauer, Till F. M., Breen, Gerome, Byrne, Enda M., Clarke, Toni-Kim, Forstner, Andreas J., Grabe, Hans J., Hamilton, Steven P., Levinson, Douglas F., Lewis, Cathryn M., Lewis, Glyn, Martin, Nicholas G., Milaneschi, Yuri, Mors, Ole, Müller-Myhsok, Bertram, Penninx, Brenda W. J. H., Perlis, Roy H., Pistis, Giorgio, Potash, James B., Preisig, Martin, Shi, Jianxin, Smoller, Jordan W., Streit, Fabien, Tiemeier, Henning, Uher, Rudolf, Van der Auwera, Sandra, Viktorin, Alexander, Weissman, Myrna M., Kendler, Kenneth S., Flint, Jonathan

“…Minimal phenotyping refers to the reliance on the use of a small number of self-reported items for disease case identification, increasingly used in…”
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Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers by Sidore, Carlo, Busonero, Fabio, Maschio, Andrea, Porcu, Eleonora, Naitza, Silvia, Zoledziewska, Magdalena, Mulas, Antonella, Pistis, Giorgio, Steri, Maristella, Danjou, Fabrice, Kwong, Alan, Ortega del Vecchyo, Vicente Diego, Chiang, Charleston W K, Bragg-Gresham, Jennifer, Pitzalis, Maristella, Nagaraja, Ramaiah, Tarrier, Brendan, Brennan, Christine, Uzzau, Sergio, Fuchsberger, Christian, Atzeni, Rossano, Reinier, Frederic, Berutti, Riccardo, Huang, Jie, Timpson, Nicholas J, Toniolo, Daniela, Gasparini, Paolo, Malerba, Giovanni, Dedoussis, George, Zeggini, Eleftheria, Soranzo, Nicole, Jones, Chris, Lyons, Robert, Angius, Andrea, Kang, Hyun M, Novembre, John, Sanna, Serena, Schlessinger, David, Cucca, Francesco, Abecasis, Gonçalo R

“…Gonçalo Abecasis, Francesco Cucca, David Schlessinger, Serena Sanna and colleagues report ~17.6 million genetic variants from whole-genome sequencing of 2,120…”
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APPLYING POLYGENIC RISK SCORING FOR PSYCHIATRIC AND METABOLIC TRAITS FOR THE PREDICTION OF MAJOR DEPRESSIVE DISORDER AND ITS SUBTYPES IN THE COLAUS|PSYCOLAUS POPULATION-BASED COHORT STUDY by Pistis, Giorgio, Mehdi, Gholam, Vandeleur, Caroline, Preisig, Martin

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Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations by Milaneschi, Yuri, Lamers, Femke, Peyrot, Wouter J, Baune, Bernhard T, Breen, Gerome, Dehghan, Abbas, Forstner, Andreas J, Grabe, Hans J, Homuth, Georg, Kan, Carol, Lewis, Cathryn, Mullins, Niamh, Nauck, Matthias, Pistis, Giorgio, Preisig, Martin, Rivera, Margarita, Rietschel, Marcella, Streit, Fabian, Strohmaier, Jana, Teumer, Alexander, Van der Auwera, Sandra, Wray, Naomi R, Boomsma, Dorret I, Penninx, Brenda W J H

“…The association between major depressive disorder (MDD) and obesity may stem from shared immunometabolic mechanisms particularly evident in MDD with atypical…”
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Genomic history of the Sardinian population by Chiang, Charleston W. K., Marcus, Joseph H., Sidore, Carlo, Biddanda, Arjun, Al-Asadi, Hussein, Zoledziewska, Magdalena, Pitzalis, Maristella, Busonero, Fabio, Maschio, Andrea, Pistis, Giorgio, Steri, Maristella, Angius, Andrea, Lohmueller, Kirk E., Abecasis, Goncalo R., Schlessinger, David, Cucca, Francesco, Novembre, John

“…The population of the Mediterranean island of Sardinia has made important contributions to genome-wide association studies of complex disease traits and, based…”
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Prevalence and correlates of DSM-5 major depressive and related disorders in the community by Vandeleur, Caroline L, Fassassi, Sylfa, Castelao, Enrique, Glaus, Jennifer, Strippoli, Marie-Pierre F, Lasserre, Aurélie M, Rudaz, Dominique, Gebreab, Sirak, Pistis, Giorgio, Aubry, Jean-Michel, Angst, Jules, Preisig, Martin

“…Abstract Although the DSM-5 has suggested the two new categories of Persistent Depressive Disorders (PDD) and Other Specified Depressive Disorders (OSDD), no…”
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Gene set enrichment analysis of pathophysiological pathways highlights oxidative stress in psychosis by Pistis, Giorgio, Vázquez-Bourgon, Javier, Fournier, Margot, Jenni, Raoul, Cleusix, Martine, Papiol, Sergi, Smart, Sophie E., Pardiñas, Antonio F., Walters, James T. R., MacCabe, James H., Kutalik, Zoltán, Conus, Philippe, Crespo-Facorro, Benedicto, Q Do, Kim

“…Polygenic risk prediction remains an important aim of genetic association studies. Currently, the predictive power of schizophrenia polygenic risk scores…”
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Genome-wide association analyses based on whole-genome sequencing in Sardinia provide insights into regulation of hemoglobin levels by Danjou, Fabrice, Zoledziewska, Magdalena, Sidore, Carlo, Steri, Maristella, Busonero, Fabio, Maschio, Andrea, Mulas, Antonella, Perseu, Lucia, Barella, Susanna, Porcu, Eleonora, Pistis, Giorgio, Pitzalis, Maristella, Pala, Mauro, Menzel, Stephan, Metrustry, Sarah, Spector, Timothy D, Leoni, Lidia, Angius, Andrea, Uda, Manuela, Moi, Paolo, Thein, Swee Lay, Galanello, Renzo, Abecasis, Gonçalo R, Schlessinger, David, Sanna, Serena, Cucca, Francesco

“…Francesco Cucca, Serena Sanna, David Schlessinger, Gonçalo Abecasis and colleagues report genome-wide association analysis results for the levels of A1, A2 and…”
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Common Variants in UMOD Associate with Urinary Uromodulin Levels: A Meta-Analysis by OLDEN, Matthias, CORRE, Tanguy, COCCA, Massimiliano, GANDIN, Ilaria, GIROTTO, Giorgia, GLAUDEMANS, Bob, HASTIE, Nicholas D, LOFFING, Johannes, POLASEK, Ozren, RAMPOLDI, Luca, RUDAN, Igor, SALA, Cinzia, HAYWARD, Caroline, TRAGLIA, Michela, VOLLENWEIDER, Peter, VUCKOVIC, Dragana, YOUHANNA, Sonia, WEBER, Julien, WRIGHT, Alan F, KUTALIK, Zoltán, BOCHUD, Murielle, FOX, Caroline S, DEVUYST, Olivier, TONIOLO, Daniela, ULIVI, Sheila, GASPARINI, Paolo, PISTIS, Giorgio, HWANG, Shih-Jen, BERGMANN, Sven, CAMPBELL, Harry

“…Uromodulin is expressed exclusively in the thick ascending limb and is the most abundant protein excreted in normal urine. Variants in UMOD, which encodes…”
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