Search Results - "Pistilli, Emidio E"

Sexual Dimorphism of Skeletal Muscle in a Mouse Model of Breast Cancer: A Functional and Molecular Analysis by Rentz, Lauren E, Whetsell, Marcella A, Clayton, Stuart A, Mizener, Alan D, Holásková, Ida, Chapa, Matthew G, Hoblitzell, Emily H, Eubank, Timothy D, Pistilli, Emidio E

“…Breast cancer incidence in men is statistically rare; however, given the lack of screening in males, more advanced stages at initial diagnosis result in lower…”
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Targeting the Activin Type IIB Receptor to Improve Muscle Mass and Function in the mdx Mouse Model of Duchenne Muscular Dystrophy by Pistilli, Emidio E, Bogdanovich, Sasha, Goncalves, Marcus D, Ahima, Rexford S, Lachey, Jennifer, Seehra, Jasbir, Khurana, Tejvir

“…The activin receptor type IIB (ActRIIB) is a transmembrane receptor for transforming growth factor-β superfamily members, including myostatin, that are…”
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Skeletal muscle gene expression in response to resistance exercise: sex specific regulation by Liu, Dongmei, Sartor, Maureen A, Nader, Gustavo A, Gutmann, Laurie, Treutelaar, Mary K, Pistilli, Emidio E, Iglayreger, Heidi B, Burant, Charles F, Hoffman, Eric P, Gordon, Paul M

“…The molecular mechanisms underlying the sex differences in human muscle morphology and function remain to be elucidated. The sex differences in the skeletal…”
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Dysregulation of metabolic‐associated pathways in muscle of breast cancer patients: preclinical evaluation of interleukin‐15 targeting fatigue by Bohlen, Joseph, McLaughlin, Sarah L., Hazard‐Jenkins, Hannah, Infante, Aniello M., Montgomery, Cortney, Davis, Mary, Pistilli, Emidio E.

“…Background Breast cancer patients report a perception of increased muscle fatigue, which can persist following surgery and standardized therapies. In a…”
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Resistance exercise training influences skeletal muscle immune activation: a microarray analysis by Gordon, Paul M, Liu, Dongmei, Sartor, Maureen A, IglayReger, Heidi B, Pistilli, Emidio E, Gutmann, Laurie, Nader, Gustavo A, Hoffman, Eric P

“…The primary aim of this investigation was to evaluate the effect of training on the immune activation in skeletal muscle in response to an acute bout of…”
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Preclinical drug trials in the mdx mouse: Assessment of reliable and sensitive outcome measures by Spurney, Christopher F., Gordish-Dressman, Heather, Guerron, Alfredo D., Sali, Arpana, Pandey, Gouri S., Rawat, Rashmi, Van Der Meulen, Jack H., Cha, Hee-Jae, Pistilli, Emidio E., Partridge, Terence A., Hoffman, Eric P., Nagaraju, Kanneboyina

“…The availability of animal models for Duchenne muscular dystrophy has led to extensive preclinical research on potential therapeutics. Few studies have focused…”
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Apoptotic responses to hindlimb suspension in gastrocnemius muscles from young adult and aged rats by Siu, Parco M, Pistilli, Emidio E, Alway, Stephen E

“…Although apoptosis has been demonstrated in soleus during hindlimb suspension (HS), it is not known whether apoptosis is also involved in the loss of muscles…”
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Death receptor-associated pro-apoptotic signaling in aged skeletal muscle by Pistilli, Emidio E, Jackson, Janna R, Alway, Stephen E

“…Tumor necrosis factor-alpha (TNF-alpha) is elevated in the serum as a result of aging and it promotes pro-apoptotic signaling upon binding to the type I TNF…”
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Akt deficiency attenuates muscle size and function but not the response to ActRIIB inhibition by Goncalves, Marcus D, Pistilli, Emidio E, Balduzzi, Anthony, Birnbaum, Morris J, Lachey, Jennifer, Khurana, Tejvir S, Ahima, Rexford S

“…Akt is a critical mediator of developmental skeletal muscle growth. Treatment with a soluble ActRIIB fusion protein (ActRIIB-mFc) increases skeletal muscle…”
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Interleukin-15 responses to aging and unloading-induced skeletal muscle atrophy by Pistilli, Emidio E, Siu, Parco M, Alway, Stephen E

“…Interleukin-15 (IL-15) mRNA is constitutively expressed in skeletal muscle. Although IL-15 has proposed hypertrophic and anti-apoptotic roles in vitro, its…”
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Rescue of a peroxisome proliferator activated receptor gamma gene network in muscle after growth of human breast tumour xenografts by Stanton, David A., Wilson, Hannah E., Chapa, Matthew G., Link, Jessica N., Lupinacci, Kristin, Geldenhuys, Werner J., Pistilli, Emidio E.

“…Background Fatigue is common in patents with breast cancer (BC), and can occur in patients with early stage disease and in the absence of muscle wasting (i.e…”
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Aging influences cellular and molecular responses of apoptosis to skeletal muscle unloading by Siu, Parco M, Pistilli, Emidio E, Butler, David C, Alway, Stephen E

“…The influence of aging on skeletal myocyte apoptosis is not well understood. In this study we examined apoptosis and apoptotic regulatory factor responses to…”
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Breast cancer-associated skeletal muscle mitochondrial dysfunction and lipid accumulation is reversed by PPARG by Wilson, Hannah E, Stanton, David A, Rellick, Stephanie, Geldenhuys, Werner, Pistilli, Emidio E

“…The peroxisome proliferator-activated receptors (PPARs) have been previously implicated in the pathophysiology of skeletal muscle dysfunction in women with…”
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Snatch Grip Overhead Shrug by Pistilli, Emidio E.

“…The snatch requires considerable power and strength to stabilize the barbell overhead in the deep squat position. Overhead strength in the catch phase of the…”
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New Perspectives for Estimating Body Composition From Computed Tomography: Clothing Associated Artifacts by Rentz, Lauren E., Malone, Briauna M., Vettiyil, Beth, Sillaste, Erik A., Mizener, Alan D., Clayton, Stuart A., Pistilli, Emidio E.

“…As the value of clinical imaging is expanded through retrospective analyses, it is imperative that all efforts are made to optimize validity. Such…”
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FER-1/Dysferlin promotes cholinergic signaling at the neuromuscular junction in C. elegans and mice by Krajacic, Predrag, Pistilli, Emidio E, Tanis, Jessica E, Khurana, Tejvir S, Lamitina, S Todd

“…Dysferlin is a member of the evolutionarily conserved ferlin gene family. Mutations in Dysferlin lead to Limb Girdle Muscular Dystrophy 2B (LGMD2B), an…”
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Interleukin-15 directly stimulates pro-oxidative gene expression in skeletal muscle in-vitro via a mechanism that requires interleukin-15 receptor alpha by O'Connell, Grant C, Pistilli, Emidio E

“…Interleukin-15 (IL-15) signaling is heavily regulated by a high specificity IL-15 binding protein known as interleukin-15 receptor alpha (IL-15Rα). In-vivo…”
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Incorporating Unilateral Variations of Weightlifting and Powerlifting Movements Into the Training Program of College-Level Dancers to Improve Stability by Pistilli, Emidio E., Mitchell, Mikaela, Florence, Lindsey

“…Properly structured resistance training can induce sport-specific neuromuscular adaptations, such as muscular strength, power, neuromuscular coordination, and…”
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Aortic dysfunction in metabolic syndrome mediated by perivascular adipose tissue TNFα‐ and NOX2‐dependent pathway by DeVallance, Evan, Branyan, Kayla W., Lemaster, Kent, Olfert, I. Mark, Smith, David M., Pistilli, Emidio E., Frisbee, Jefferson C., Chantler, Paul D.

“…New Findings What is the central question of this study? Tumour necrosis factor‐α (TNFα) has been shown to impair vascular function, but the impact of thoracic…”
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Age-dependent increase in oxidative stress in gastrocnemius muscle with unloading by Siu, Parco M, Pistilli, Emidio E, Alway, Stephen E

“…1 Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China; and 2 Laboratory of Muscle…”
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