Search Results - "Pistell, Paul J"

High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling by Morrison, Christopher D, Pistell, Paul J, Ingram, Donald K, Johnson, William D, Liu, Ying, Fernandez-Kim, Sun Ok, White, Christy L, Purpera, Megan N, Uranga, Romina M, Bruce-Keller, Annadora J, Keller, Jeffrey N

“…J. Neurochem. (2010) 114, 1581-1589. Long term consumption of a high fat diet (HFD) contributes to increased morbidity and mortality. Yet the specific effects…”
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Effects of high fat diet on Morris maze performance, oxidative stress, and inflammation in rats: Contributions of maternal diet by White, Christy L, Pistell, Paul J, Purpera, Megan N, Gupta, Sunita, Fernandez-Kim, Sun-Ok, Hise, Taylor L, Keller, Jeffrey N, Ingram, Donald K, Morrison, Christopher D, Bruce-Keller, Annadora J

“…Abstract This study was undertaken to investigate the effects of prenatal and postnatal exposure to high fat diet on the brain. Female rats were divided into…”
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An Avocado Extract Enriched in Mannoheptulose Prevents the Negative Effects of a High-Fat Diet in Mice by Pistell, Paul J, Utsuki, Tadanobu, Francis, Joseph, Ebenezer, Philip J, Terrebonne, Jennifer, Roth, George S, Ingram, Donald K

“…Beginning at 16 weeks of age and continuing for 44 weeks, male C57BL/6J were fed either a control (CON) diet; a high-fat (HF) diet (60% unsaturated); or the HF…”
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NOX activity in brain aging: Exacerbation by high fat diet by Bruce-Keller, Annadora J., White, Christy L., Gupta, Sunita, Knight, Alecia G., Pistell, Paul J., Ingram, Donald K., Morrison, Christopher D., Keller, Jeffrey N.

“…This study describes how age and high fat diet affect the profile of NADPH oxidase (NOX). Specifically, NOX activity and subunit expression were evaluated in…”
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Cognitive impairment following high fat diet consumption is associated with brain inflammation by Pistell, Paul J, Morrison, Christopher D, Gupta, Sunita, Knight, Alecia G, Keller, Jeffrey N, Ingram, Donald K, Bruce-Keller, Annadora J

“…Abstract C57Bl/6 mice were administered a high fat, Western diet (WD, 41% fat) or a very high fat lard diet (HFL, 60% fat), and evaluated for cognitive ability…”
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Feed efficiency, food choice, and food reward behaviors in young and old Fischer rats by Frutos, Miriam García-San, Pistell, Paul J, Ingram, Donald K, Berthoud, Hans-Rudolf

“…Abstract Increased susceptibility to energy imbalance and anorexia in old age are risk factors for malnutrition during aging, but the underlying mechanisms are…”
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Characterization and Mechanisms of Action of Avocado Extract Enriched in Mannoheptulose as a Candidate Calorie Restriction Mimetic by Ingram, Donald K, Pistell, Paul J, Wang, Zhong Q, Yu, Yongmei, Massimino, Stefan, Davenport, Gary M, Hayek, Michael, Roth, George S

“…Increased consumer interest in the avocado (Persea americana or Persea gratissima) has been attributed to established health benefits of this fruit associated…”
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Resveratrol improves health and survival of mice on a high-calorie diet by Baur, J.A, Pearson, K.J, Price, N.L, Jamieson, H.A, Lerin, C, Kalra, A, Prabhu, V.V, Allard, J.S, Lopez-Lluch, G, Lewis, K

“…Resveratrol (3,5,4'-trihydroxystilbene) extends the lifespan of diverse species including Saccharomyces cerevisiae, Caenorhabditis elegans and Drosophila…”
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Phosphodiesterase inhibition facilitates cognitive restoration in rodent models of age-related memory decline by Devan, Bryan D, Pistell, Paul J, Duffy, Kara B, Kelley-Bell, Bennett, Spangler, Edward L, Ingram, Donald K

“…Previous studies have shown that cyclic nucleotide phosphodiesterase type 5 (PDE5) inhibition with the drugs sildenafil and vardenafil can enhance spatial…”
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Age-associated learning and memory deficits in two mouse versions of the stone T-maze by Pistell, Paul J, Spangler, Edward L, Kelly-Bell, Bennett, Miller, Marshall G, de Cabo, Rafael, Ingram, Donald K

“…Abstract We have previously reported that a modified Stone T-maze (STM), using escape from water as motivation, was effective in evaluating learning and memory…”
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Metabolic and neurologic consequences of chronic lopinavir/ritonavir administration to C57BL/6 mice by Pistell, Paul J., Gupta, Sunita, Knight, Alecia G., Domingue, Michelle, Uranga, Romina M., Ingram, Donald K., Kheterpal, Indu, Ruiz, Carmen, Keller, Jeffrey N., Bruce-Keller, Annadora J.

“…It is well established that HIV antiretroviral drugs, particularly protease inhibitors, frequently elicit a metabolic syndrome that may include hyperlipidemia,…”
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Interleukin-15 Receptor Is Essential to Facilitate GABA Transmission and Hippocampal-Dependent Memory by He, Yi, Hsuchou, Hung, Wu, Xiaojun, Kastin, Abba J, Khan, Reas S, Pistell, Paul J, Wang, Wei-Hsung, Feng, Jiming, Li, Zengbiao, Guo, Xiaochuan, Pan, Weihong

“…Interleukin-15 (IL15) is a cytokine produced by normal brain, but the functions of the IL15 system in normal adults are not yet clear. The hypothesis that the…”
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Apoptotic and behavioral sequelae of mild brain trauma in mice by Tweedie, David, Milman, Anat, Holloway, Harold W., Li, Yazhou, Harvey, Brandon K., Shen, Hui, Pistell, Paul J., Lahiri, Debomoy K., Hoffer, Barry J., Wang, Yun, Pick, Chaim G., Greig, Nigel H.

“…Mild traumatic brain injury (mTBI) is a not uncommon event in adolescents and young adults. Although it does not result in clear morphological brain defects,…”
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XRCC1 haploinsufficiency in mice has little effect on aging, but adversely modifies exposure-dependent susceptibility by McNeill, Daniel R., Lin, Ping-Chang, Miller, Marshall G., Pistell, Paul J., de Souza-Pinto, Nadja C., Fishbein, Kenneth W., Spencer, Richard G., Liu, Yie, Pettan-Brewer, Christina, Ladiges, Warren C., Wilson, David M.

“…Oxidative DNA damage plays a role in disease development and the aging process. A prominent participant in orchestrating the repair of oxidative DNA damage,…”
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Effect of intrastriatal mesenchymal stromal cell injection on progression of a murine model of Krabbe disease by Wicks, Shawna E., Londot, Heaven, Zhang, Bo, Dowden, Jennifer, Klopf-Eiermann, Jessica, Fisher-Perkins, Jeanne M., Trygg, Cynthia B., Scruggs, Brittni A., Zhang, Xiujuan, Gimble, Jeffrey M., Bunnell, Bruce A., Pistell, Paul J.

“…► Intrastriatal mesenchymal stromal cell injection in twitcher mouse model of Krabbe. ► Minor improvements in rotarod and twitching severity at certain stages…”
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Tolerance, fermentation, and cytokine expression in healthy aged male C57BL/6J mice fed resistant starch by Zhou, June, Keenan, Michael J., Keller, Jeffrey, Fernandez-Kim, Sun O., Pistell, Paul J., Tulley, Richard T., Raggio, Anne M., Shen, Li, Zhang, Hanjie, Martin, Roy J., Blackman, Marc R.

“…Health benefits of resistant starch (RS), a dietary fermentable fiber, have been well documented in young, but not in old populations. As the essential step of…”
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Dietary resistant starch improves selected brain and behavioral functions in adult and aged rodents by Zhou, June, Keenan, Michael J., Fernandez-Kim, Sun Ok, Pistell, Paul J., Ingram, Donald K., Li, Bing, Raggio, Anne M., Shen, Li, Zhang, Hanjie, McCutcheon, Kathleen L., Tulley, Richard T., Blackman, Marc R., Keller, Jeffrey N., Martin, Roy J.

“…Resistant starch (RS) is a dietary fiber that exerts multiple beneficial effects. The current study explored the effects of dietary RS on selected brain and…”
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Accelerated cognitive aging in diabetic rats is prevented by lowering corticosterone levels by Stranahan, Alexis M., Lee, Kim, Pistell, Paul J., Nelson, Christopher M., Readal, Nathaniel, Miller, Marshall G., Spangler, Edward L., Ingram, Donald K., Mattson, Mark P.

“…Diabetes and normal aging are both characterized by increases in levels of glucocorticoids. Because long-term exposure to elevated glucocorticoids can be…”
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Striatal lesions interfere with acquisition of a complex maze task in rats by Pistell, Paul J., Nelson, Chris M., Miller, Marshall G., Spangler, Edward L., Ingram, Donald K., Devan, Bryan D.

“…The 14-unit T-maze has proven to be a valuable tool for investigating age-associated memory impairment (AAMI). While another task widely used to evaluate AAMI,…”
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Sildenafil citrate attenuates a complex maze impairment induced by intracerebroventricular infusion of the NOS inhibitor N ω-nitro- L-arginine methyl ester by Devan, Bryan D., Pistell, Paul J., Daffin, Lee W., Nelson, Christopher M., Duffy, Kara B., Bowker, Jonna L., Bharati, Ila S., Sierra-Mercado, Demetrio, Spangler, Edward L., Ingram, Donald K.

“…In a previous study, our laboratory reported that sildenafil citrate, a cyclic nucleotide phosphodiesterase type 5 inhibitor, reversed a learning impairment in…”
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