Search Results - "Pissurlenkar, Raghuvir R. S."

Interaction of multimicrobial synthetic inhibitor 1,2-bis(2-benzimidazolyl)-1,2-ethanediol with serum albumin: spectroscopic and computational studies by Kamtekar, Nayana, Pandey, Anita, Agrawal, Neeraj, Pissurlenkar, Raghuvir R S, Borana, Mohanish, Ahmad, Basir

“…The molecule, 1,2-Bis(2-benzimidazolyl)-1,2-ethanediol (BBE) is known to act as a selective inhibitor of poliovirus, rhinovirus, Candida albicans, several…”
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Size-Induced Chiral Discrimination Switching by (S)-(−)-2(α-Hydroxyethyl)Benzimidazole-Derived Azacrowns by Pandey, Anita D., Mohammed, Hasan, Pissurlenkar, Raghuvir R. S., Karnik, Anil V.

“…(S)‐(−)‐2‐(α‐Hydroxyethyl)benzimidazole (1)‐derived diastereomeric monoaza‐[18]crown‐6 compounds 5 and 6 were synthesised with an additional chiral centre…”
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Synthesis, in vitro antitubercular activity and 3D-QSAR study of 1,4-dihydropyridines by Manvar, Atul T, Pissurlenkar, Raghuvir R. S, Virsodia, Vijay R, Upadhyay, Kuldip D, Manvar, Dinesh R, Mishra, Arun K, Acharya, Hrishikesh D, Parecha, Alpesh R, Dholakia, Chintan D, Shah, Anamik K, Coutinho, Evans C

“…In continuation of our research program on new antitubercular agents, this article is a report of the synthesis of 97 various symmetrical, unsymmetrical, and…”
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Effects of 2-amino-8-hydroxyquinoline interaction on the conformation of physiological isomers of human serum albumin by Shiriskar, Sonali M., Agarwal, Neeraj, Pissurlenkar, Raghuvir R. S., Ahmad, Basir

“…The methods of synthetic chemistry create small molecules rapidly for screening, and ligand–protein interaction studies provide information on how a potential…”
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Valsartan inclusion by methyl-β-cyclodextrin: Thermodynamics, molecular modelling, Tween 80 effect and evaluation by Chadha, Renu, Bala, Madhu, Arora, Poonam, Jain, D.V.S., Pissurlenkar, Raghuvir R.S., Coutinho, Evans C.

“…•The effect of M-β-CD and Tween 80 (0.5%, v/v) on solubility and biological performance of valsartan has been evaluated.•The mode of interaction, stoichiometry…”
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Molecular modeling studies, synthesis, and biological evaluation of Plasmodium falciparum enoyl-acyl carrier protein reductase (PfENR) inhibitors by Morde, Varun A, Shaikh, Mushtaque S, Pissurlenkar, Raghuvir R. S, Coutinho, Evans C

“…The search for new antimalarial agents is necessary as current drugs in the market become vulnerable due to the emergence of resistance strains of Plasmodium…”
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Synthesis, screening for antitubercular activity and 3D-QSAR studies of substituted N-phenyl-6-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydro-pyrimidine-5-carboxamides by Virsodia, Vijay, Pissurlenkar, Raghuvir R.S., Manvar, Dinesh, Dholakia, Chintan, Adlakha, Priti, Shah, Anamik, Coutinho, Evans C.

“…Multi-drug resistance to commonly used antitubercular drugs has propelled the development of new structural classes of antitubercular agents. This paper…”
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Telmisartan complex augments solubility, dissolution and drug delivery in prostate cancer cells by Kaur, Manveet, Bhatia, Richa Kaur, Pissurlenkar, Raghuvir R.S., Coutinho, Evans C., Jain, Upendra Kumar, Katare, Om Prakash, Chandra, Ramesh, Madan, Jitender

“…•Telmisartan inhibits the growth of prostate cancer cells with low therapeutic index.•We have synthesized a complex of telmisartan using the carbohydrate…”
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Furo-Fused BINOL Based Crown as a Fluorescent Chiral Sensor for Enantioselective Recognition of Phenylethylamine and Ethyl Ester of Valine by Upadhyay, Sunil P, Pissurlenkar, Raghuvir R. S, Coutinho, Evans C, Karnik, Anil V

“…A furo-fused BINOL based chiral crown was developed as an enantioselective chiral sensor for phenylethylamine and ethyl ester of valine. Fusion of furan to…”
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HomoSAR: Bridging comparative protein modeling with quantitative structural activity relationship to design new peptides by Borkar, Mahesh R., Pissurlenkar, Raghuvir R. S., Coutinho, Evans C.

“…Peptides play significant roles in the biological world. To optimize activity for a specific therapeutic target, peptide library synthesis is inevitable; which…”
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Comprehensive computational study in the identification of novel potential cholesterol lowering agents targeting proprotein convertase subtilisin/kexin type 9 by Maliwal, Deepika, Pissurlenkar, Raghuvir R. S., Telvekar, Vikas

“…The enzymatic target proprotein convertase subtilisin/kexin type 9 (PCSK9) is critically involved in the regulation of the lipoprotein metabolism leading to…”
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Targeting Dormant Tuberculosis Bacilli: Results for Molecules with a Novel Pyrimidone Scaffold by Joshi, Rohit R., Barchha, Avinash, Khedkar, Vijay M., Pissurlenkar, Raghuvir R. S., Sarkar, Sampa, Sarkar, Dhiman, Joshi, Rohini R., Joshi, Ramesh A., Shah, Anamik K., Coutinho, Evans C.

“…Our inability to completely control TB has been due in part to the presence of dormant mycobacteria. This also renders drug regimens ineffective and is the…”
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Characterization of pioglitazone cyclodextrin complexes: Molecular modeling to in vivo evaluation by Bramhane, Dinesh, Kulkarni, Preethi, Martis, Elvis, Pissurlenkar, Raghuvir, Coutinho, Evans, Nagarsenker, Mangal

“…Aims: The objective of present study was to study the influence of different β-cyclodextrin derivatives and different methods of complexation on aqueous…”
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Synthesis, biological screening and in silico studies of new N-phenyl-4-(1,3-diaryl-1H-pyrazol-4-yl)thiazol-2-amine derivatives as potential antifungal and antitubercular agents by Nandurkar, Yogesh, Bhoye, Manish R., Maliwal, Deepika, Pissurlenkar, Raghuvir R.S., Chavan, Abhijit, Katade, Sushma, Mhaske, Pravin C.

“…A new series of N-aryl-4-(1,3-diaryl-1H-pyrazol-4-yl)thiazol-2-amine, (8a-x) have been synthesized by a cyclo-condensation reaction of…”
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Curcumin and kaempferol prevent lysozyme fibril formation by modulating aggregation kinetic parameters by Borana, Mohanish S., Mishra, Pushpa, Pissurlenkar, Raghuvir R.S., Hosur, Ramakrishna V., Ahmad, Basir

“…Interaction of small molecule inhibitors with protein aggregates has been studied extensively, but how these inhibitors modulate aggregation kinetic parameters…”
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The reorganization of conformations, stability and aggregation of serum albumin isomers through the interaction of glycopeptide antibiotic teicoplanin: A thermodynamic and spectroscopy study by Muthu, Shivani A., Jadav, Helly Chetan, Srivastava, Sadhavi, Pissurlenkar, Raghuvir R.S., Ahmad, Basir

“…The drugs-protein binding study is of growing importance for drug-repurposing against amyloidosis. In this work, we study the binding of teicoplanin (TPN), a…”
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New thiazolyl-isoxazole derivatives as potential anti-infective agents: design, synthesis, in vitro and in silico antimicrobial efficacy by Bhoye, Manish R, Shinde, Abhijit, Shaikh, Abdul Latif N, Shisode, Vilas, Chavan, Abhijit, Maliwal, Deepika, Pissurlenkar, Raghuvir R S, Mhaske, Pravin C

“…Antimicrobial resistance threatens the efficacious prevention and treatment of infectious diseases caused by microorganisms. To combat microbial infections,…”
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Physical basis for the ofloxacin-induced acceleration of lysozyme aggregation and polymorphism in amyloid fibrils by Muthu, Shivani A., Mothi, Nivin, Shiriskar, Sonali M., Pissurlenkar, Raghuvir R.S., Kumar, Anil, Ahmad, Basir

“…Aggregation of globular proteins is an intractable problem which generally originates from partially folded structures. The partially folded structures first…”
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The cocrystal of 3-((4-(3-isocyanobenzyl) piperazine-1-yl) methyl) benzonitrile with 5-hydroxy isophthalic acid prevents protofibril formation of serum albumin by Shabbir, Sadiya, Muslim, Mohd, Muthu, Shivani A., Pissurlenkar, Raghuvir R. S., Fatima, Shaista, Ali, Arif, Ahmad, Aiman, Ahmad, Musheer, Ahmad, Basir

“…The formation of amyloid-like fibrils is a central problem in biophysical chemistry and medicine. Fibril formation and their deposition in various tissues and…”
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Synthesis, anticancer evaluation and in silico studies of novel N‐substituted arylidenethiazolidine‐2,4‐dione derivatives as adenosine monophosphate‐activated protein kinase activators by Chothani, Savankumar R., Chamakiya, Chirag A., Joshi, Rupal J., Karmur, Manisha B., Karmur, Sheetal B., Varu, Hardik L., Pissurlenkar, Raghuvir R. S., Patel, Anilkumar S., Kapuriya, Naval P.

“…Abstract Design and development of AMP‐activated protein kinase (AMPK) activator emerged as a potential therapeutic approach for various types of cancers. In…”
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