Search Results - "Piso, Katherine"
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In Vivo Emergence of a Novel Mutant L159F/L320F in the NS5B Polymerase Confers Low-Level Resistance to the HCV Polymerase Inhibitors Mericitabine and Sofosbuvir
Published in The Journal of infectious diseases (01-03-2014)“…Background. Resistance to mericitabine (prodrug of HCV NS5B polymerase inhibitor PSI-6130) is rare and conferred by the NS5B S282T mutation. Methods. Serum HCV…”
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Impact of indication changes on scoping for European Union Joint Clinical Assessment: scale of the problem and how to address it
Published in International journal of technology assessment in health care (25-11-2024)“…ObjectivesThe European Union Joint Clinical Assessment (JCA) process aligns with the regulatory process to promote faster patient access. The PICO (population,…”
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PDCD2 controls hematopoietic stem cell differentiation during development
Published in Stem cells and development (01-01-2013)“…Programmed cell death 2 (Pdcd2) is a highly conserved protein of undefined function, and is widely expressed in embryonic and adult tissues. The observations…”
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The Role of ETV6/TEL in Hematopoiesis and Lymphoid Neoplasia
Published in Blood (20-11-2009)“…Abstract 972 The transcriptional repressor TEL (Translocation Ets Leukemia) also known as ETV6 (Ets variant gene 6) located on human chromosome 12 is essential…”
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Alternative Splicing of PDCD2 Regulates Hematopoietic Stem Cell Specification, and Drives Multilineage Leukemia Development
Published in Blood (20-11-2009)“…Abstract 258 PDCD2 (Programmed cell death domain 2) is a highly conserved zinc finger MYND domain-containing nuclear protein expressed in a variety of tissues…”
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