Search Results - "Piskurich, Janet F"
-
1
Positive Regulatory Domain I (PRDM1) and IRF8/PU.1 Counter-regulate MHC Class II Transactivator (CIITA) Expression during Dendritic Cell Maturation
Published in The Journal of biological chemistry (11-03-2011)“…Dendritic cells (DCs) are key mediators of immune function through robust and tightly regulated presentation of antigen in the context of the MHC Class II. MHC…”
Get full text
Journal Article -
2
Innate and Adaptive Immune Response to a Virus: An Integrated Learning Module
Published in MedEdPORTAL (28-09-2018)“…Medical schools must expand their teaching strategies to address a new generation of medical students and ensure their growth into lifelong, self-directed…”
Get full text
Journal Article -
3
BLIMP-1 mediates extinction of major histocompatibility class II transactivator expression in plasma cells
Published in Nature immunology (01-12-2000)“…Class II transactivator (CIITA), a coactivator required for class II major histocompatibility complex (MHC) transcription, is expressed in B cells but…”
Get full text
Journal Article -
4
Immune Response to Bacteria: An Integrated Learning Module to Enhance Preclinical Students' Competency in Immunology
Published in MedEdPORTAL (23-05-2017)“…Medical students express frustration that they cannot assemble a comprehensive big picture of how the immune system responds to a microbe and that integration…”
Get full text
Journal Article -
5
Immune Response in Allergic Contact Dermatitis: An Integrated Learning Module
Published in MedEdPORTAL (12-02-2018)“…Medical students are introduced to skin rashes during their preclinical years and often express difficulty in differentiating the underlying mechanisms. The…”
Get full text
Journal Article -
6
Class II Transactivator (CIITA) Promoter Methylation Does Not Correlate with Silencing of CIITA Transcription in Trophoblasts
Published in Biology of reproduction (01-09-2003)“…Trophoblast cells are unique because they do not express major histocompatibility complex (MHC) class II antigens, either constitutively or after exposure to…”
Get full text
Journal Article -
7
Cutting Edge: Coordinate Regulation of IFN Regulatory Factor-1 and the Polymeric Ig Receptor by Proinflammatory Cytokines
Published in The Journal of immunology (1950) (01-02-1999)“…The polymeric IgR (pIgR) mediates transcytosis of IgA across epithelial barriers of mucous membranes and exocrine glands. Synthesis of pIgR is up-regulated by…”
Get full text
Journal Article -
8
Immune Response to an Intracellular Microbe (Virus)
Published in MedEdPORTAL (23-05-2013)“…Abstract Introduction Immunology can be a difficult discipline for first- and second-year medical students. Many, learning the various parts of the immune…”
Get full text
Journal Article -
9
Two Distinct Gamma Interferon-Inducible Promoters of the Major Histocompatibility Complex Class II Transactivator Gene Are Differentially Regulated by STAT1, Interferon Regulatory Factor 1, and Transforming Growth Factor β
Published in Molecular and Cellular Biology (01-01-1999)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
10
Positive regulatory domain I-binding factor 1 mediates repression of the MHC class II transactivator (CIITA) type IV promoter
Published in Molecular Immunology (01-02-2007)“…MHC class II transactivator (CIITA), a co-activator that controls MHC class II (MHC II) transcription, functions as the master regulator of MHC II expression…”
Get full text
Journal Article -
11
MHC class II transactivator (CIITA) expression is upregulated in multiple myeloma cells by IFN-γ
Published in Molecular immunology (01-04-2007)“…The MHC class II transactivator (CIITA) acts in the cell nucleus as the master regulator of MHC class II (MHC II) gene expression. It is important to study…”
Get full text
Journal Article -
12
The Role of the MHC Class II Transactivator in Class II Expression and Antigen Presentation by Astrocytes and in Susceptibility to Central Nervous System Autoimmune Disease
Published in The Journal of immunology (1950) (15-12-2002)“…The role of the MHC class II transactivator (CIITA) in Ag presentation by astrocytes and susceptibility to experimental autoimmune encephalomyelitis (EAE) was…”
Get full text
Journal Article -
13
Expression of the MHC class II transactivator (CIITA) type IV promoter in B lymphocytes and regulation by IFN-γ
Published in Molecular immunology (01-02-2006)“…The MHC class II transactivator (CIITA), the master regulator of MHC class II (MHC II) expression, is a co-activator that controls MHC II transcription. Human…”
Get full text
Journal Article -
14
Regulation and Specificity of MHC2TA Promoter Usage in Human Primary T Lymphocytes and Cell Line
Published in The Journal of immunology (1950) (15-09-2002)“…Although activated human T cells express MHC class II antigens, the regulation of these antigens in T cells is poorly understood. This study focuses on the…”
Get full text
Journal Article -
15
A Novel Element and a TEF-2-like Element Activate the Major Histocompatibility Complex Class II Transactivator in B-lymphocytes
Published in The Journal of biological chemistry (05-11-1999)“…Major histocompatibility complex (MHC) class II molecules play a central role in immune responses, and transcription of this family of genes requires the MHC…”
Get full text
Journal Article -
16
Differential selectivity of CIITA promoter activation by IFN-γ and IRF-1 in astrocytes and macrophages: CIITA promoter activation is not affected by TNF-α
Published in Journal of neuroimmunology (29-10-1999)“…During demyelinating disease of the central nervous system (CNS), locally elevated cytokine levels may induce upregulation of MHC class II molecules on…”
Get full text
Journal Article -
17
Class II Transactivator (CIITA) Promoter Methylation Does Not Correlate with Silencing of CIITA Transcription in Trophoblasts1
Published in Biology of reproduction (01-09-2003)“…Trophoblast cells are unique because they do not express major histocompatibility complex (MHC) class II antigens, either constitutively or after exposure to…”
Get full text
Journal Article -
18
Prolonged survival of class II transactivator-deficient cardiac allografts
Published in Transplantation (15-11-2002)“…Major histocompatibility complex (MHC) antigenic complexes trigger allogeneic T-cell responses and allograft rejection. MHC class II and related antigen…”
Get full text
Journal Article -
19
Integrating Immunology into a Clinical Presentation-Based Medical School Curriculum (37.4)
Published in The Journal of immunology (1950) (01-04-2009)“…Immunology can be a difficult discipline for first and second year medical students. As a teacher or learning facilitator it is sometimes hard to decide where…”
Get full text
Journal Article -
20
B Lymphocyte-Induced Maturation Protein-1/Positive Regulatory Domain I-Binding Factor 1 regulates two amino peptidases associated with antigen processing (78.9)
Published in The Journal of immunology (1950) (01-04-2009)“…A diverse repertoire of specifically-trimmed peptides is presented by the Major Histocompatibility Complex Class I (MHCI) pathway of antigen presentation for…”
Get full text
Journal Article