Search Results - "Piser, T."

Validation of a suite of ERP and QEEG biomarkers in a pre-competitive, industry-led study in subjects with schizophrenia and healthy volunteers by Cecchi, M., Adachi, M., Basile, A., Buhl, D.L., Chadchankar, H., Christensen, S., Christian, E., Doherty, J., Fadem, K.C., Farley, B., Forman, M.S., Honda, S., Johannesen, J., Kinon, B.J., Klamer, D., Marino, M.J., Missling, C., O'Donnell, P., Piser, T., Puryear, C.B., Quirk, M.C., Rotte, M., Sanchez, C., Smith, D.G., Uslaner, J.M., Javitt, D.C., Keefe, R.S.E., Mathalon, D., Potter, W.Z., Walling, D.P., Ereshefsky, L.

“…Complexity and lack of standardization have mostly limited the use of event-related potentials (ERPs) and quantitative EEG (QEEG) biomarkers in drug…”
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Cannabinoid Receptor Agonists Inhibit Glutamatergic Synaptic Transmission in Rat Hippocampal Cultures by Shen, Maoxing, Piser, Timothy M, Seybold, Virginia S, Thayer, Stanley A

“…Activation of cannabinoid receptors inhibits voltage-gated Ca2+ channels and activates K+ channels, reminiscent of other G-protein-coupled signaling pathways…”
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Omega-grammotoxin SIA blocks multiple, voltage-gated, Ca2+ channel subtypes in cultured rat hippocampal neurons by Piser, T M, Lampe, R A, Keith, R A, Thayer, S A

“…Omega-Grammotoxin SIA is a peptide isolated from tarantula venom on the basis of its ability to block the voltage-gated Ca2+ channels that mediate glutamate…”
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HIV-1 envelope protein evokes intracellular calcium oscillations in rat hippocampal neurons by Lo, T M, Fallert, C J, Piser, T M, Thayer, S A

“…Treatment of single rat hippocampal neurons with 200 pM recombinant HIV-1 envelope glycoprotein, gp120, resulted in large increases in the intracellular free…”
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Neuronal nicotinic receptor modulating drugs targeting Schizophrenia by Piser, T

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ω-grammotoxin blocks action-potential-induced Ca2+ influx and whole-cell Ca2+ current in rat dorsal-root ganglion neurons by PISER, T. M, LAMPE, R. A, KEITH, R. A, THAYER, S. A

“…Field-potential stimulation of rat dorsal-root ganglion (DRG) neurons evoked action-potential-mediated transient increases in intracellular free calcium…”
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3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors Protect Cortical Neurons from Excitotoxicity by Zacco, Anna, Togo, James, Spence, Katherine, Ellis, Amanda, Lloyd, Darlene, Furlong, Steve, Piser, Timothy

“…3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitors, or statins, reduce the incidence of strokes and reduce infarct volume after cerebral ischemia in…”
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Complete and reversible block by ω-grammotoxin SIA of glutamatergic synaptic transmission between cultured rat hippocampal neurons by Piser, Timothy M., Lampe, Richard A., Keith, Richard A., Thayer, Stanley A.

“…ω-Grammotoxin SIA (ω-GsTx SIA), a peptide isolated from tarantula venom, inhibits synaptosomal Ca 2+ influx and neurotransmitter release, and blocks N-, P-,…”
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Effects of stimulus intensity on the inhibition by omega-conotoxin GVIA and neomycin of K(+_-evoked [3H]norepinephrine release from hippocampal brain slices and synaptosomal calcium influx by Keith, R A, Horn, M B, Piser, T M, Mangano, T J

“…The effects of various K+ concentrations on the inhibition of [3H]norepinephrine release from rat hippocampal brain slices and evoked synaptosomal 45Ca2+…”
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Differential coupling of M1 muscarinic and alpha7 nicotinic receptors to inhibition of pemphigus acantholysis by Chernyavsky, Alex I, Arredondo, Juan, Piser, Timothy, Karlsson, Evert, Grando, Sergei A

“…The mechanisms mediating and regulating assembly and disassembly of intercellular junctions is a subject of intensive research. The IgG autoantibodies produced…”
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Cloning and characterization of two K super(+) inward rectifier (K sub(ir)) 1.1 potassium channel homologs from human kidney (K sub(ir)1.2 and K sub(ir)1.3) by Shuck, ME, Piser, T M, Bock, J H, Slightom, J L, Lee, K S, Bienkowski, MJ

“…The DNA sequence encoding the rat brain inward rectifier-10 K super(+) channel was amplified from rat brain RNA using reverse transcription-polymerase chain…”
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Grammotoxin blocks action-potential-induced Ca2+ influx and whole-cell Ca2+ current in rat dorsal-root ganglion neurons by Piser, T. M., Lampe, R. A., Keith, R. A., Thayer, S. A.

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omega -Grammotoxin blocks action-potential-induced Ca super(2+) influx and whole-cell Ca super(2+) current in rat dorsal-root ganglion neurons by Piser, T M, Lampe, R A, Keith, R A, Thayer, SA

“…Field-potential stimulation of rat dorsal-root ganglion (DRG) neurons evoked action-potential-mediated transient increases in intracellular free calcium…”
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Cloning and Characterization of Two K+ Inward Rectifier (Kir) 1.1 Potassium Channel Homologs from Human Kidney (Kir1.2 and Kir1.3) by Shuck, M E, Piser, T M, Bock, J H, Slightom, J L, Lee, K S, Bienkowski, M J

“…The DNA sequence encoding the rat brain inward rectifier-10 K + channel was amplified from rat brain RNA using reverse transcription-polymerase chain reaction…”
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Purification, characterization and catalytic properties of human sterol 8-isomerase by Nes, W David, Zhou, Wenxu, Dennis, Allen L, Li, Haoxia, Jia, Zhonghua, Keith, Richard A, Piser, Timothy M, Furlong, Stephen T

“…CHO 2, encoding human sterol 8-isomerase (hSI), was introduced into plasmids pYX213 or pET23a. The resulting native protein was overexpressed in erg 2 yeast…”
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Microplate gel-filtration method for radioligand-binding assays by Liu, Jianwei, Zacco, Anna, Piser, Timothy M, Scott, Clay W

“…A thin-layer gel-filtration chromatographic method has been developed in a 96-well format to separate free and protein-bound ligand in radioligand-binding…”
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