Search Results - "Pisconti, A"

Elastase levels and activity are increased in dystrophic muscle and impair myoblast cell survival, proliferation and differentiation by Arecco, N., Clarke, C. J., Jones, F. K., Simpson, D. M., Mason, D., Beynon, R. J., Pisconti, A.

“…In Duchenne muscular dystrophy, progressive loss of muscle tissue is accompanied by fibrosis, chronic inflammation and reduced muscle regenerative capacity…”
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Dynamic changes in heparan sulfate during muscle differentiation and ageing regulate myoblast cell fate and FGF2 signalling by Ghadiali, R.S., Guimond, S.E., Turnbull, J.E., Pisconti, A.

“…Satellite cells (SCs) are skeletal muscle stem cells residing quiescent around healthy muscle fibres. In response to injury or disease SCs activate,…”
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Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation by De Palma, C, Falcone, S, Pisoni, S, Cipolat, S, Panzeri, C, Pambianco, S, Pisconti, A, Allevi, R, Bassi, M T, Cossu, G, Pozzan, T, Moncada, S, Scorrano, L, Brunelli, S, Clementi, E

“…During myogenic differentiation the short mitochondria of myoblasts change into the extensively elongated network observed in myotubes. The functional…”
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P63 Improving satellite cell regenerative potential in muscular dystrophy: an environmental issue by Pisconti, A, Olwin, B.B

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Interleukin-12 p40/p70 ratio and in vivo responsiveness to IFN-alpha treatment in chronic hepatitis C by Piazzolla, G, Tortorella, C, Fiore, G, Fanelli, M, Pisconti, A, Antonaci, S

“…To evaluate the relationship between cytokine balance and responsiveness to interferon-alpha (IFN-alpha), we investigated the production of IFN-gamma,…”
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Characterization of the large-conductance Ca-activated K channel in myocytes of rat saphenous artery by Catacuzzeno, L, Pisconti, D A, Harper, A A, Petris, A, Franciolini, F

“…We used the patch-clamp method to characterize the BK channel in freshly isolated myocytes from the saphenous branch of the rat femoral artery. Single-channel…”
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Mitochondrial Biogenesis by NO Yields Functionally Active Mitochondria in Mammals by Nisoli, Enzo, Falcone, Sestina, Tonello, Cristina, Cozzi, Valeria, Palomba, Letizia, Fiorani, Mara, Pisconti, Addolorata, Brunelli, Silvia, Cardile, Annalisa, Francolini, Maura, Cantoni, Orazio, Carruba, Michele O., Moncada, Salvador, Clementi, Emilio, Ignarro, Louis J.

“…We recently found that long-term exposure to nitric oxide (NO) triggers mitochondrial biogenesis in mammalian cells and tissues by activation of guanylate…”
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P57 STEM CELL PLASTICITY AND TUMORIGENISIS: REGULATORY ROLES OF HEPARAN SULPHATE IN THE CANCER STEM CELL NICHE by Baty, R., Pisconti, A., Turnbull, J.

“…INTRODUCTION: During the past few years, stem cells have received attention as a system for research and cell-based therapies due to their unique ability for…”
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Follistatin induction by nitric oxide through cyclic GMP: a tightly regulated signaling pathway that controls myoblast fusion by Pisconti, Addolorata, Brunelli, Silvia, Di Padova, Monica, De Palma, Clara, Deponti, Daniela, Baesso, Silvia, Sartorelli, Vittorio, Cossu, Giulio, Clementi, Emilio

“…The mechanism of skeletal myoblast fusion is not well understood. We show that endogenous nitric oxide (NO) generation is required for myoblast fusion both in…”
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Activation of Acid Sphingomyelinase and Its Inhibition by the Nitric Oxide/Cyclic Guanosine 3',5'-Monophosphate Pathway: Key Events in Escherichia coli-Elicited Apoptosis of Dendritic Cells by Falcone, Sestina, Perrotta, Cristiana, De Palma, Clara, Pisconti, Addolorata, Sciorati, Clara, Capobianco, Annalisa, Rovere-Querini, Patrizia, Manfredi, Angelo A, Clementi, Emilio

“…Depletion of dendritic cells (DCs) via apoptosis contributes to sepsis-induced immune suppression. The mechanisms leading to DC apoptosis during sepsis are not…”
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Impaired Interleukin-12-Dependent T-Cell Functions During Aging: Role of Signal Transducer and Activator of Transcription 4 (STAT4) and Suppressor of Cytokine Signaling 3 (SOCS3) by Tortorella, Cosimo, Stella, Isabella, Piazzolla, Giuseppina, Cappiello, Valentina, Simone, Olivia, Pisconti, Addolorata, Antonaci, Salvatore

“…Interleukin (IL)-12 is the major inducer of T helper cell (Th) 1-type responses. Despite a higher IL-12 production, phytohemagglutinin (PHA)-stimulated…”
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Nitric oxide confers therapeutic activity to dendritic cells in a mouse model of melanoma by PERROTTA, Cristiana, FALCONE, Sestina, CLEMENTI, Emilio, CAPOBIANCO, Annalisa, CAMPOREALE, Annalisa, SCIORATI, Clara, DE PALMA, Clara, PISCONTI, Addolorata, ROVERE-QUERINI, Patrizia, BELLONE, Matteo, MANFREDI, Angelo A

“…Susceptibility of dendritic cells (DCs) to tumor-induced apoptosis reduces their efficacy in cancer therapy. Here we show that delivery within exponentially…”
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APC-dependent impairment of T cell proliferation in aging: role of CD28- and IL-12/IL-15-mediated signaling by Tortorella, Cosimo, Pisconti, Addolorata, Piazzolla, Giuseppina, Antonaci, Salvatore

“…The age-related impairment of phytohaemagglutinin (PHA)-triggered peripheral blood mononuclear cell (PBMC) proliferation was paralleled by an expansion of CD28…”
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