Search Results - "Pisarenko, O I"
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Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 2. Treatment of some ROS- and Age-related diseases (heart arrhythmia, heart infarctions, kidney ischemia, and stroke)
Published in Biochemistry (Moscow) (01-12-2008)“…Effects of 10-(6′-plastoquinonyl) decyltriphenylphosphonium (SkQ1) and 10-(6′-plastoquinonyl) decylrhod-amine 19 (SkQR1) on rat models of H 2 O 2 - and…”
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2
Apelin-12 and its structural analog enhance antioxidant defense in experimental myocardial ischemia and reperfusion
Published in Molecular and cellular biochemistry (01-06-2014)“…This study investigated the effects of peptide apelin-12 (H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH, A12) and its novel structural analog (H-(N α…”
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3
Synthesis of the Antagonist of the GalR2 Galanin Receptor and Studies of Its Biological Activity in Ischemia and Reperfusion of the Rat Heart In Vivo
Published in Russian journal of bioorganic chemistry (01-10-2022)“…The dose-dependent action of the M871 synthetic peptide antagonist of the GalR2 galanin receptor…”
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Anti-Ischemic and Antioxidant Activity of the Pharmacological Agonist of Galanin Receptor GalR2 and Carnosine in In Vitro and In Vivo Model Systems
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-12-2022)“…Antioxidant and anti-ischemic properties of the pharmacological agonist of galanin receptor GalR2 WTLNSAGYLLGPβAH (Gal) and its C-terminal fragment, dipeptide…”
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5
Identifying the Formation Cause of Ghost Line (Contour) Macrostructure Defects
Published in Steel in translation (01-04-2021)“…State Standard GOST 4543–2016 stipulates for more stringent requirements of ghost line (contour) macrostructure defects for alloyed steel. State Standard GOST…”
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The mechanisms of cardiac protection using a synthetic agonist of galanin receptors during chronic administration of doxorubicin
Published in Actanaturae (01-01-2020)“…The use of the anticancer drug doxorubicin (Dox) is limited by its cardiotoxic effect. The aim of this work was to study the effect of a new synthetic agonist…”
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Convergent Synthesis of the Rat Galanin and Study of Its Biological Activity
Published in Russian journal of bioorganic chemistry (2020)“…The full-length rat galanin (GWTLNSAGYLLGPHAIDNHRSFSDKHGLT-NH 2 , G29) was prepared by the solid phase peptide synthesis using the Fmoc-strategy. The peptide…”
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Fragments of the Galanin Peptide and Their Synthetic Analogues with the Cardioprotective Effect
Published in Russian journal of bioorganic chemistry (01-09-2019)“…New peptide analogs of galanin corresponding to fragments of the N -terminal sequence were synthesized by an automatic solid-phase method using…”
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Optimization of the Synthesis of an Apelin-12 Structural Analog and the NMR Study of Its Stability in Human Plasma
Published in Russian journal of bioorganic chemistry (2019)“…A method for the solid-phase synthesis of the apelin-12 analog has been developed using the Fmoc methodology in combination with the temporary protection of…”
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Protective Action of a Modified Galanin Fragment in Rats with Doxorubicin-Induced Heart Failure
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-04-2019)“…The clinical application of the anticancer agent doxorubicin (Dox) is limited due to its cardiotoxic effect. Using the method of automated solid-phase peptide…”
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Antioxidant Action of Apelin-12 Peptide and Its Structural Analog In Vitro
Published in Bulletin of experimental biology and medicine (01-09-2015)“…The effects of C-terminal fragment of natural peptide apelin-12 H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH (A12) and its structural analog H-(N α…”
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Contractile Function of Isolated Hearts With Preserved and Reduced Ejection Fraction In Vivo
Published in Kardiologiia (01-04-2018)“…The aim of the study was comparison of contractile function of isolated hearts of rats with doxorubicin-induced myocardial injury which were tentatively…”
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In Vivo Reduction of Reperfusion Injury to the Heart with Apelin-12 Peptide in Rats
Published in Bulletin of experimental biology and medicine (01-11-2011)“…Apelin-12 (A-12) peptide was synthesized by automated solid phase method and purified by reverse phase HPLC. Its homogeneity and structure were confirmed by…”
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Inhibitor of beta-hydroxy-beta-methylglutaryl coenzyme A reductase decreases energy supply to the myocardium in rats
Published in Bulletin of experimental biology and medicine (01-10-2001)“…Hypocholesterolemic preparations, inhibitors of the key enzyme of cholesterol biosynthesis beta-hydroxy-beta-methylglutaryl coenzyme A reductase (statins),…”
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Involvement of NO-dependent mechanisms of apelin action in myocardial protection against ischemia/reperfusion damage
Published in Kardiologiia (2012)“…Apelin 12 (A-12) was synthesized by the automatic solid phase method with the use of Fmoc technology. The synthesized peptide was purified by preparative HPLC…”
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Limitation of myocardial infarction by a structural analog of the peptide apelin-12
Published in Doklady. Biological sciences (01-04-2012)Get full text
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Antioxidant properties of apelin-12 and its structural analogue in experimental ischemia and reperfusion
Published in Kardiologiia (2013)“…Effects of apelin-12 H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH (A12) and its modified analogue…”
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Cardiac metabolism and performance during L-glutamic acid infusion in postoperative cardiac failure
Published in Clinical science (1979) (01-01-1986)“…Intravenous infusion of L-glutamic acid results in the augmentation of the cardiac output and an improvement of the circulation in patients with postoperative…”
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Human recombinant extracellular-superoxide dismutase type C improves cardioplegic protection against ischemia/reperfusion injury in isolated rat heart
Published in Journal of cardiovascular pharmacology (01-10-1994)“…The cardioprotective effects of human recombinant extracellular-superoxide dismutase type C (hr-EC-SOD C) were compared with those of bovine Cu,Zn-SOD in…”
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Effects of exogenous apelin-12 on functional and metabolic recovery of isolated rat heart after ischemia
Published in Kardiologiia (2010)“…Apelin 12 (A 12) was synthesized by the automatic solid phase method with the use of Fmoc technology. The synthesized peptide was purified by preparative HPLC…”
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